Development of a serum protein biomarker panel for the diagnosis of pancreatic ductal adenocarcinoma using a machine learning approach. [PDF]
Shin DW +4 more
europepmc +1 more source
Tubular Biomarkers and Retinal Microvasculature: Illuminating Early Cardiovascular-Kidney-Metabolic Pathways Beyond the Glomerulus. [PDF]
Cohen-Hagai K.
europepmc +1 more source
Profibrinolytic Factors and Cancer Progression, Metastasis, and Survival. [PDF]
Hisada Y, Mackman N.
europepmc +1 more source
Assessment of Cardiorenal Involvement in Systemic Sclerosis Patients. [PDF]
Pellicano C +9 more
europepmc +1 more source
Validation of suPAR turbidimetric assay on Cobas® (c502 and c702) and comparison to suPAR ELISA
suPAR is a plasma marker of chronic inflammation, and an elevated suPAR is consistently associated with worse outcome in a variety of clinical conditions. Quantification of suPAR is useful for determining patient risk in triage, but there is no fast automatized method for quick determination of suPAR.
Skovsted, Thor A. +5 more
openaire +4 more sources
The Inflammatory Marker suPAR After Cardiac Arrest
Soluble urokinase plasminogen activator receptor (suPAR) is released in response to inflammatory stimuli, and plasma levels are associated with long-term outcomes. The ischemia/reperfusion injury caused by cardiac arrest (CA) and resuscitation triggers an inflammatory response. This pilot study aimed at investigating suPAR levels in relation to outcome
Malin, Rundgren +3 more
openaire +3 more sources
SuPAR, an emerging biomarker in kidney and inflammatory diseases [PDF]
AbstractSoluble urokinase plasminogen activator receptor (suPAR) is a circulating form of a physiological and pathophysiological important cell surface receptor, implicated in inflammation. Recent studies showed that suPAR is a promising biomarker, useful for diagnosis, assessment and prognosis of several diseases.
Lamiaa Hamie +8 more
openaire +3 more sources
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suPAR and chronic kidney disease—a podocyte story
Pflugers Archiv European Journal of Physiology, 2017The soluble urokinase-type plasminogen activator receptor (suPAR) is a circulating signaling molecule derived from immature myeloid cells. Elevated levels of suPAR have been linked to the pathogenesis of the kidney disease focal and segmental glomerulosclerosis. Here, suPAR acts on podocytes by activating αvβ3 integrins.
Jochen Reiser +2 more
exaly +3 more sources
SuPAR, a potential inflammatory mediator in psoriasis pathogenesis [PDF]
Abstract Psoriasis is an inflammatory skin disorder that is strongly associated with the metabolic syndrome. The sole reliance on clinical examination to guide prognostication and treatment is insufficient at best; accurate diagnostic and prognostic psoriatic molecular biomarkers are needed.
Lamiaa Hamie +15 more
openaire +3 more sources
An ELISA method detecting the active form of suPAR
Talanta, 2016Urokinase plasminogen activator receptor (uPAR) exists in a number of formats in human plasma, including soluble uPAR (suPAR) and uPAR fragments. We developed an ELISA method to detect specifically the active form suPAR, which binds to its natural ligand uPA. The intra CV and inter CV of this ELISA assay is 8.5% and 9.6% respectively, and the assay can
Zafar Iqbal, Cai Yuan, Mingdong Huang
exaly +3 more sources

