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Inflammation, 2010 Udgivelsesdato: 2010-DecPlasma levels of the inflammatory biomarker soluble urokinase plasminogen activator (suPAR) have been shown to carry prognostic information in various infectious and inflammatory diseases.
Andreas Andersen +2 more
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A suPAR Biomarker for Chronic Kidney Disease
New England Journal of Medicine, 2015The worldwide epidemic of chronic kidney disease — an insidious illness that manifests with asymptomatic reductions in the estimated glomerular filtration rate (eGFR) to less than 60 ml per minute per 1.73 m2 of body-surface area, excessive urinary excretion of protein, or both — afflicts an estimated 600 million people.1 Many will have progression to ...
Karl L, Skorecki, Barry I, Freedman
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suPAR in cardiovascular disease
Soluble urokinase plasminogen activator receptor (suPAR), the soluble counterpart of urokinase plasminogen activator receptor, is found in the circulation at various levels. suPAR and its parent molecule, cell surface uPAR, exhibit similar structure and extracellular functional roles facilitating fibrinolysis, cellular adhesion, and migration.Jaya, Montecillo +3 more
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2012
La reconnaissance precoce des patients septiques les plus a risque permet une prise en charge adaptee dans les plus brefs delais, seule garante d’une amelioration du pronostic, tandis que la reconnaissance des malades les moins severes permet de limiter les temps de sejour aux urgences, et de prioriser les ressources.
D. Barraud, S. Gibot
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La reconnaissance precoce des patients septiques les plus a risque permet une prise en charge adaptee dans les plus brefs delais, seule garante d’une amelioration du pronostic, tandis que la reconnaissance des malades les moins severes permet de limiter les temps de sejour aux urgences, et de prioriser les ressources.
D. Barraud, S. Gibot
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PP071. suPAR levels in normal- and preeclamptic pregnancies
Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2013Preeclampsia (PE) has been considered to be a maternal inflammatory response to pregnancy and may be hazardous for mother and child. Soluble urokinase Plasminogen Activator receptor (suPAR) is a non-specific marker that reflects overall systemic inflammation and immune activation.We examined the levels of suPAR in first and third trimesters of normal ...
Nancy, Odden +4 more
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suPAR as a biomarker of support in different clinical settings
Clinica Chimica ActaThe urokinase-type plasminogen activator receptor (uPAR) system, which includes protease, receptor and inhibitors, is essential for key cellular functions like immune activation, cell migration, and tissue remodeling. Soluble uPAR (suPAR), released into circulation, serves as a valuable biomarker for systemic inflammation and immune activation ...
Fabio, Belvederi +3 more
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suPAR: A New Biomarker for Cardiovascular Disease?
Canadian Journal of Cardiology, 2015The fundamental role of inflammation in cardiovascular disease (CVD) has prompted interest in numerous biomarkers that detect subclinical levels of inflammation. Soluble urokinase plasminogen activator receptor (suPAR) is a novel biomarker that correlates significantly with cardiovascular events and outperforms traditional markers of inflammation such ...
Gethin W. Hodges +4 more
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suPAR news for acute kidney injury?
Science Translational Medicine, 2020suPAR might serve as a biomarker for prediction of acute kidney injury with possible therapeutic implications.
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suPAR Cut-Offs for Risk Stratification in Patients With Symptoms of COVID-19
Biomarker Insights, 2021Izzet Altintas +2 more
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