Results 11 to 20 of about 5,026 (202)
suPAR: The Molecular Crystal Ball [PDF]
Disease Markers, 2009 soluble urokinase Plasminogen Activator Receptor (suPAR) levels reflect inflammation and elevated suPAR levels are found in several infectious diseases and cancer. suPAR exists in three forms; suPAR I-III , suPAR II-III and suPAR I
Thunø, Maria +2 more
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suPAR as a prognostic biomarker in sepsis [PDF]
BMC Medicine, 2012 Abstract Sepsis is the clinical syndrome derived from the host response to an infection and severe sepsis is the leading cause of death in critically ill patients. Several biomarkers have been tested for use in diagnosis and prognostication in patients with sepsis.
DONADELLO, Katia +3 more
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The Association of suPAR with Cardiovascular Risk Factors in Young and Healthy Adults [PDF]
Diagnostics, 2023 The soluble urokinase plasminogen activator receptor (suPAR), as a correlate of chronic low-grade inflammation, may be used to predict individual cardiovascular risk.
Niklas Fabio Wohlwend +7 more
doaj +3 more sources
Validation of suPAR turbidimetric assay on Cobas® (c502 and c702) and comparison to suPAR ELISA
Scandinavian Journal of Clinical and Laboratory Investigation, 2020 suPAR is a plasma marker of chronic inflammation, and an elevated suPAR is consistently associated with worse outcome in a variety of clinical conditions. Quantification of suPAR is useful for determining patient risk in triage, but there is no fast automatized method for quick determination of suPAR.
Skovsted, Thor A. +5 more
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Circulating suPAR in Two Cohorts of Primary FSGS [PDF]
Journal of the American Society of Nephrology, 2012 Overexpression of soluble urokinase receptor (suPAR) causes pathology in animal models similar to primary FSGS, and one recent study demonstrated elevated levels of serum suPAR in patients with the disease. Here, we analyzed circulating suPAR levels in two cohorts of children and adults with biopsy-proven primary FSGS: 70 patients from the North ...
ÖZALTIN, FATİH +19 more
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Detection of Inflammatory Biomarker suPAR in COVID-19 Disease With CHORUS TRIO Instrument [PDF]
Biomarker Insights, 2023 Background: Deregulation in the urokinase-type plasminogen activator receptor (uPA/uPAR) system is reported in many diseases where the immune system is activated.
Cerutti Helena +9 more
doaj +2 more sources
Healthy lifestyles reduce suPAR and mortality in a Danish general population study [PDF]
Immunity & Ageing, 2019 Background The plasma level of the inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is a strong predictor of disease development and premature mortality in the general population.
Thomas Huneck Haupt +6 more
doaj +2 more sources
Significance of suPAR in glomerular diseases
Linchuang shenzangbing zazhi, 2020 The soluble urokinase-type plasminogen activator receptor(suPAR) is a new type of biomarkers, and can be used for a variety of diagnosis, evaluation and prognosis of many diseases. Numerous studies have proved that suPAR is closely related to inflammatory diseases, cardiovascular diseases, autoimmune diseases, tumors and chronic liver diseases.
RUAN Dong-dong, YUAN Jun
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SuPAR, an emerging biomarker in kidney and inflammatory diseases [PDF]
Postgraduate Medical Journal, 2018 AbstractSoluble urokinase plasminogen activator receptor (suPAR) is a circulating form of a physiological and pathophysiological important cell surface receptor, implicated in inflammation. Recent studies showed that suPAR is a promising biomarker, useful for diagnosis, assessment and prognosis of several diseases.
Lamiaa Hamie +8 more
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SuPAR, a potential inflammatory mediator in psoriasis pathogenesis [PDF]
Clinical and Experimental Pharmacology and Physiology, 2020 Abstract Psoriasis is an inflammatory skin disorder that is strongly associated with the metabolic syndrome. The sole reliance on clinical examination to guide prognostication and treatment is insufficient at best; accurate diagnostic and prognostic psoriatic molecular biomarkers are needed.
Lamiaa Hamie +15 more
openaire +3 more sources