Results 11 to 20 of about 4,267 (203)
suPAR: The Molecular Crystal Ball [PDF]
Disease Markers, 2009 soluble urokinase Plasminogen Activator Receptor (suPAR) levels reflect inflammation and elevated suPAR levels are found in several infectious diseases and cancer. suPAR exists in three forms; suPARI-III, suPARII-IIIand suPARIwhich show different properties due to structural differences. Studies suggest that full-length suPAR is a regulator of uPAR/uPA
Thunø, Maria +2 more
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Circulating suPAR in Two Cohorts of Primary FSGS [PDF]
Journal of the American Society of Nephrology, 2012 Overexpression of soluble urokinase receptor (suPAR) causes pathology in animal models similar to primary FSGS, and one recent study demonstrated elevated levels of serum suPAR in patients with the disease. Here, we analyzed circulating suPAR levels in two cohorts of children and adults with biopsy-proven primary FSGS: 70 patients from the North ...
Wei, Changli +19 more
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suPAR as a prognostic biomarker in sepsis [PDF]
BMC Medicine, 2012 Abstract Sepsis is the clinical syndrome derived from the host response to an infection and severe sepsis is the leading cause of death in critically ill patients. Several biomarkers have been tested for use in diagnosis and prognostication in patients with sepsis.
DONADELLO, Katia +3 more
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The Association of suPAR with Cardiovascular Risk Factors in Young and Healthy Adults [PDF]
Diagnostics, 2023 The soluble urokinase plasminogen activator receptor (suPAR), as a correlate of chronic low-grade inflammation, may be used to predict individual cardiovascular risk.
Niklas Fabio Wohlwend +7 more
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The role of suPAR in kidney diseases
Annales Academiae Medicae Silesiensis, 2017 Przewlekła choroba nerek (PChN) to niewątpliwie problem o znaczeniu społecznym, dotyczy bowiem około 10% populacji. Poszukiwane są biomarkery, dzięki którym spośród tak dużej liczby pacjentów udałoby się wyselekcjonować osoby z dużym ryzykiem progresji choroby i jej powikłań.
Mirosław Śnit +3 more
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Brain, Behavior, & Immunity - Health, 2023 Introduction: Inflammation has been associated with depression and differential antidepressant (AD) treatment response. Soluble urokinase plasminogen activator receptor (suPAR) is a novel measure of chronic inflammation.
T.H. Haupt +4 more
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Healthy lifestyles reduce suPAR and mortality in a Danish general population study [PDF]
Immunity & Ageing, 2019 Background The plasma level of the inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is a strong predictor of disease development and premature mortality in the general population.
Thomas Huneck Haupt +6 more
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Significance of suPAR in glomerular diseases
Linchuang shenzangbing zazhi, 2020 The soluble urokinase-type plasminogen activator receptor(suPAR) is a new type of biomarkers, and can be used for a variety of diagnosis, evaluation and prognosis of many diseases. Numerous studies have proved that suPAR is closely related to inflammatory diseases, cardiovascular diseases, autoimmune diseases, tumors and chronic liver diseases.
RUAN Dong-dong, YUAN Jun
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suPAR as a marker of infection in acute kidney injury – a prospective observational study [PDF]
BMC Nephrology, 2018 Background Soluble urokinase-type plasminogen activator receptor (suPAR) has emerged as a new sepsis biomarker. It is not known whether suPAR has a role in critically ill patients with severe acute kidney injury (AKI).
Anna Hall +4 more
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Kinetics of the soluble urokinase plasminogen activator receptor (suPAR) in cirrhosis. [PDF]
PLoS ONE, 2019 BackgroundThe soluble urokinase plasminogen activator receptor (suPAR) is related to hepatic inflammation and fibrosis and has been suggested to participate in the development of liver cirrhosis. Therefore, the aim of the current study was to measure the
Emilie Garnæs +5 more
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