Results 31 to 40 of about 3,556,805 (146)

Super-Refractory Status Epilepticus

Clinical EEG and Neuroscience, 2014
Super-refractory status epilepticus (SE; ie, SE continuing or recurring despite 24 hours of general anesthesia) is a severe condition with high percentage of mortality and morbidity. Usually, this condition occurs because of serious brain damage; nevertheless, some patients develop super-refractory SE without identifiable etiology.
Lapenta, L, Frisullo, Giovanni, Vollono, Catello, Brunetti, V, Giannantoni, Nm, Sandroni, Claudio, Di Lella, Giuseppe Maria, Della Marca, Giacomo   +7 more
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Refractory and Super-Refractory Status Epilepticus

Neurologic Clinics
In patients with status epilepticus (SE), the underlying biologic background represents the main prognostic variable. A swift application of a treatment protocol is recommended, including adequate doses of a benzodiazepine followed by an intravenous anti-
Rossetti, A.O.
openaire   +2 more sources

Refractory and Super-refractory Status Epilepticus [PDF]

Indian Pediatrics, 2020
Refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE) are neurological emergencies with considerable mortality and morbidity. In this paper, we provide an overview of causes, evaluation, treatment, and consequences of RSE and SRSE, reflecting the lack of high-quality evidence to inform therapeutic approach.This is a ...
Samanta, Debopam, Garrity, Lisa, Arya, Ravindra   +2 more
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Ketamine to treat super-refractory status epilepticus

Neurology, 2020
To test ketamine infusion efficacy in the treatment of super-refractory status epilepticus (SRSE), we studied patients with SRSE who were treated with ketamine retrospectively. We also studied the effect of high doses of ketamine on brain physiology as reflected by invasive multimodality monitoring (MMM).We studied a consecutive series of 68 patients ...
Ayham Alkhachroum, Caroline A. Der-Nigoghossian, Elizabeth Mathews, Nina Massad, Riva Letchinger, Kevin Doyle, Wei-Ting Chiu, Julie Kromm, Clio Rubinos, Angela Velazquez, David Roh, Sachin Agarwal, Soojin Park, E. Sander Connolly, Jan Claassen   +14 more
openaire   +3 more sources

Ketamine use in refractory status epilepticus associated with anti-NMDA receptor antibody encephalitis

Epilepsy & Behavior Reports, 2019
Purpose: Anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDAr encephalitis) is an auto-immune disorder associated with the production of antibodies against NR1 and NR2 sub units of the NMDA receptor.
Jonathan D. Santoro, MD, Alexandra Filippakis, DO, Tanuja Chitnis, MD   +2 more
doaj   +1 more source

Pediatric super refractory status: An intensivists perspective

Journal of Pediatric Critical Care, 2019
Super refractory status epilepticus was a term used first in the Third London-Innsbruck Colloquium on status epilepticus held in Oxford. It can be estimated that about 15% of all the cases with status epilepticus admitted to hospital become super ...
Romit Saxena, Mohan Kundal, Puneet Jain, Amarjeet Chitkara, Tanuj Verma, Arun Kumar   +5 more
doaj   +1 more source

Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study.

, 2021
OBJECTIVES: To characterize the pediatric super-refractory status epilepticus population by describing treatment variability in super-refractory status epilepticus patients and comparing relevant clinical characteristics, including outcomes, between ...
Guerriero, Rejean M, Sánchez-Fernández, Iván, McDonough, Tiffani L, Piantino, Juan, Sands, Tristan T, Loddenkemper, Tobias, Brenton, James N, Carpenter, Jessica L, Abend, Nicholas S, Wainwright, Mark S, Chapman, Kevin, Anderson, Anne, Wilfong, Angus, Sannagowdara, Kumar, Payne, Eric T, Riviello, James J, Arya, Ravindra, Gaillard, William D, Goldstein, Joshua L, Goodkin, Howard P, Peariso, Katrina, Topjian, Alexis, Clark, Justice, Amengual-Gual, Marta, Ostendorf, Adam P, Mikati, Mohamad A, Vasquez, Alejandra, Farias-Moeller, Raquel, Tchapyjnikov, Dmitry, Glauser, Tracy, Williams, Korwyn, Novotny, Edward J, Lai, Yi-Chen, Morgan, Lindsey A, Tasker, Robert C   +34 more
core   +1 more source

Thiopentone Induced Paralytic Ileus in Super Refractory Status Epilepticus: Erythromycin to the Rescue [PDF]

Journal of Clinical and Diagnostic Research, 2017
Neurocritical care, a unique specialty requiring skill and adeptness presents us with many challenging situations. Management of super refractory status epilepticus warrants the use of intravenous anaesthetic agents and along with it comes its various ...
Karen Ruby Lionel, Ajay Prasad Hrishi
doaj   +1 more source

Intravenous ganaxolone in pediatric super-refractory status epilepticus: A single hospital experience

Epilepsy & Behavior Reports, 2022
Synaptic GABAA receptor (GABAAR) internalization contributes to the drug resistant nature of super-refractory status epilepticus (SRSE). Ganaxolone is a 3β-methylated synthetic analog of the endogenous neuroactive steroid, allopregnanolone, that has ...
Rani K. Singh, Rajdeep Singh, Alejandra Stewart, Katherine Van Poppel, Sarah Klinger, Joseph Hulihan, Heather Van Heusen, Henrikas Vaitkevicius, Maciej Gasior   +8 more
doaj   +1 more source

Recent progress of drug therapy in status epilepticus

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Status epilepticus (SE) is a critical and emergency condition in internal medicine and neurology. Recently, the concepts, definition, and classification of SE are revised, followed by renew of the protocol of management of SE.
LU Qin⁃chi
doaj   +1 more source