Results 41 to 50 of about 1,493 (172)

Isoflurane in (Super-) Refractory Status Epilepticus: A Multicenter Evaluation [PDF]

Neurocritical Care, 2021
AbstractBackgroundWe aimed to determine the association between seizure termination and side effects of isoflurane for the treatment of refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE) in neurointensive care units (neuro-ICUs).MethodsThis was a multicenter retrospective study of patients with RSE/SRSE treated with ...
Stetefeld, Henning R., Schaal, Alexander, Scheibe, Franziska, Herzig-Nichtweiß, Julia, Lehmann, Felix, Müller, Marcus, Gerner, Stefan T., Huttner, Hagen B., Luger, Sebastian, Fuhrer, Hannah, Bösel, Julian, Schönenberger, Silvia, Dimitriadis, Konstatinos, Neumann, Bernhard, Fuchs, Kornelius, Fink, Gereon R., Malter, Michael P., IGNITE, Study group   +17 more
openaire   +5 more sources

Super-Refractory Status Epilepticus: An Atypical Presentation and Case-Based Review

Archives of Epilepsy, 2015
Super-refractory status epilepticus is known to typically arise either from a distinct underlying cause or, in patients with no history of epilepsy, from no overt cause.
Chiazor Udochukwu ONYIA, Morenikeji A. KOMOLAFE, Ayo M. ADEBIYI, Olusegun OYEWOLE, Fola A. FAPONLE   +4 more
doaj   +1 more source

Neurostimulation in the treatment of refractory and super-refractory status epilepticus [PDF]

Epilepsy & Behavior, 2019
Status epilepticus (SE) is a life-threatening condition with a mortality of up to 60% in the advanced and comatose forms of SE. In one out of five adults, first and second line fails to control epileptic activity, leading to refractory status epilepticus (RSE) and in around 3% to super-refractory status epilepticus (SRSE), where SE continues despite ...
Trinka, Eugen, Brigo, Francesco
openaire   +3 more sources

Management of super refractory status epilepticus

Anaesthesia, Pain & Intensive Care, 2020
Super refractory status epilepticus ( SRSE ) is the status epilepticus in which the seizures continue for 24 hour or more after anesthetic medications to control and reappear when the patient is weaned from the anesthetic agent. Characteristic seizures are distinguished, by the presence and/or absence of motor seizure, into convulsive and non ...
Wardah Rahmatul Islamiyah, Hanik Badriyah Hidayati, Abdulloh Machin, Dedy Kurniawan   +3 more
openaire   +2 more sources

Burden of illness for super-refractory status epilepticus patients [PDF]

Journal of Medical Economics, 2016
To provide an estimate of the annual number of super-refractory status epilepticus (SRSE) cases in the US and to evaluate utilization of hospital resources by these patients.The Premier Hospital Database was utilized to estimate the number of SRSE cases based on hospital discharges during 2012.
Jamil M. Beg, Thomas D. Anderson, Kevin Francis, Lisa M. Meckley, David Fitzhenry, Todd Foster, Susheel Sukhtankar, Stephen J. Kanes, Lidia M. V. R. Moura   +8 more
openaire   +2 more sources

Study of refractory status epilepticus from a tertiary care center

Annals of Indian Academy of Neurology, 2017
Objectives: To determine the proportion of refractory status epilepticus (RSE) and super-RSE (SRSE) among patients with status epilepticus (SE) and to analyze RSE and non-RSE (NRSE) in terms of etiology and predictors for RSE.
Sahil Kohli, Suresh Babu Pasangulapati, Sangeetha Yoganathan, Gideon Lyngsyun Rynjah, A T Prabhakar, Sanjith Aaron, Mathew Alexander, Vivek Mathew   +7 more
doaj   +1 more source

Super Refractory Status Epilepticus

, 2017
Earlier definitions of status epilepticus (SE) were based on the duration of seizures, but newer definitions rely more on a pragmatic staging based on treatment failures (Table 23.1). Refractory status epilepticus (RSE) is defined as SE that continues despite administration of both benzodiazepines and an appropriately dosed second-line antiseizure drug.
Zachariah, Joseph, Britton, Jeff, Hocker, Sara   +2 more
openaire   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Management of Status Epilepticus

Journal of Neuroanaesthesiology and Critical Care, 2019
Status epilepticus (SE) is a life-threatening neurologic condition that requires immediate assessment and intervention. Over the past few decades, the duration of seizure required to define status epilepticus has shortened, reflecting the need to start ...
Ritesh Lamsal, Navindra R. Bista
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source