Results 51 to 60 of about 4,192 (239)

Fenfluramine in the successful treatment of super-refractory status epilepticus in a patient with Dravet syndrome

Epilepsy & Behavior Reports, 2021
A 20-year-old woman with Dravet syndrome and multiple prior episodes of status epilepticus presented to our hospital in November 2018 in super-refractory status epilepticus.
David Millett, Suzanne Pach
doaj   +1 more source

Brexanolone as adjunctive therapy in super‐refractory status epilepticus [PDF]

Annals of Neurology, 2017
ObjectiveSuper‐refractory status epilepticus (SRSE) is a life‐threatening form of status epilepticus that continues or recurs despite 24 hours or more of anesthetic treatment. We conducted a multicenter, phase 1/2 study in SRSE patients to evaluate the safety and tolerability of brexanolone (USAN; formerly SAGE‐547 Injection), a proprietary, aqueous ...
Eric S. Rosenthal, Jan Claassen, Mark S. Wainwright, Aatif M. Husain, Henrikas Vaitkevicius, Shane Raines, Ethan Hoffmann, Helen Colquhoun, James Doherty, Stephen Kanes   +9 more
openalex   +3 more sources

Electroconvulsive therapy for new-onset super-refractory status epilepticus [PDF]

Hong Kong Medical Journal, 2018
Eric LY Chan, Wen‐Chung Lee, CK Koo, Horace ST King, CT Woo, S-H Ng   +5 more
openalex   +3 more sources

Realising the therapeutic potential of neuroactive steroid modulators of the GABA_A receptor [PDF]

, 2020
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia, Gee, Kelvin W., Hogenkamp, Derk, Lambert, Jeremy J.   +3 more
core   +1 more source

Neuromodulation Techniques in Children with Super-Refractory Status Epilepticus [PDF]

Brain Sci, 2023
Status epilepticus (SE) is a life-threatening condition and medical emergency which can have lifelong consequences, including neuronal death and alteration of neuronal networks, resulting in long-term neurologic and cognitive deficits in children. When standard pharmacological treatment for SE is not successful in controlling seizures, the condition ...
Stavropoulos I, Pak H, Alarcon G, Valentin A.   +3 more
europepmc   +4 more sources

Is Favorable Outcome Possible After Prolonged Refractory Status Epilepticus? [PDF]

, 2016
When status epilepticus (SE) remains refractory to appropriate therapy, it is associated with high mortality and with substantial morbidity in survivors.
Alvarez, V., Drislane, F.W.
core   +1 more source

Isoflurane in (Super-) Refractory Status Epilepticus: A Multicenter Evaluation [PDF]

Neurocritical Care, 2021
AbstractBackgroundWe aimed to determine the association between seizure termination and side effects of isoflurane for the treatment of refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE) in neurointensive care units (neuro-ICUs).MethodsThis was a multicenter retrospective study of patients with RSE/SRSE treated with ...
Henning Stetefeld, Alexander Schaal, Franziska Scheibe, Julia Herzig-Nichtweiß, Felix Lehmann, Marcus Müller, Stefan T. Gerner, Hagen B. Huttner, Sebastian Luger, Hannah Fuhrer, Julian Bösel, Silvia Schönenberger, Konstantinos Dimitriadis, Bernhard Neumann, Kornelius Fuchs, Gereon R. Fink, Michael P. Malter, the IGNITE Study Group, with support from the German Neurocritical Care Society (DGNI)   +17 more
openalex   +8 more sources

13 Prognostication in super refractory status epilepticus: Preliminary results from an international survey study [PDF]

J Clin Transl Sci
Woodward M, Brown J, Badjatia N, Morris N, Johnson E, Gilmore E.   +5 more
europepmc   +3 more sources

New-Onset Refractory Status Epilepticus with Claustrum Damage: Definition of the Clinical and Neuroimaging Features [PDF]

, 2017
New-onset refractory status epilepticus (NORSE) is a rare but challenging condition occurring in a previously healthy patient, often with no identifiable cause.
Alexopoulos, Haris, D'Orsi, Giuseppe, GIOVANNINI, GIADA, Guha, Rahul, Kiryttopoulos, Andreas, Martino, Tommaso, MELETTI, Stefano, MONTI, Giulia, Pascarella, Maria Grazia, Slonkova, Jana, Spilioti, Martha, Toran, Lisa   +11 more
core   +1 more source

Endosulfan-Induced Prolonged Super-Refractory Status Epilepticus [PDF]

Journal of Epilepsy Research, 2018
Endosulfan is a highly toxic pesticide that causes hyperstimulation of the central nervous system by antagonizing gamma aminobutyric acid-mediated inhibition. Seizure is the most important manifestation of endosulfan poisoning, frequently progressing to status epilepticus and refractory status epilepticus. Here, we report a recent case of a 64-year-old
Park, Hea Ree, Song, Pamela, Lee, Jae Jung, Cho, Joong-Yang   +3 more
openaire   +2 more sources