Results 71 to 80 of about 1,493 (172)

New onset refractory status epilepticus (NORSE) versus refractory status epilepticus not meeting NORSE criteria: A comparative clinical and electroencephalography‐based study

Epilepsia, EarlyView.
Abstract Objective New onset refractory status epilepticus (NORSE) is a rare, severe presentation of refractory status epilepticus (RSE), with approximately half of cases cryptogenic NORSE (c‐NORSE). We compared electroencephalographic (EEG) findings alongside clinical features between NORSE and RSE not meeting NORSE criteria to better understand ...
Seren Hawksworth, Nina Moutonnet, Gregory Scott, Sanjeev Rajakulendran, Mahinda Yogarajah, Matthew C. Walker, Umesh Vivekananda   +6 more
wiley   +1 more source

Surgical management of status epilepticus: A systematic review

Epilepsia Open
Status Epilepticus (SE), unresponsive to medical management, is associated with high morbidity and mortality. Surgical management is typically considered in these refractory cases. The best surgical approach for affected patients remains unclear; however,
Rohan Jha, Sarah E. Blitz, Melissa M. J. Chua, Aaron E. L. Warren, Jong Woo Lee, John D. Rolston   +5 more
doaj   +1 more source

Status epilepticus in adults: From etiology to treatment response

Epilepsia, EarlyView.
Abstract This study explored the association between etiology of status epilepticus (SE) and treatment responsiveness. Consecutive episodes of nonhypoxic SE in patients ≥14 years old were included. Etiology was classified into acute, remote, progressive, defined electroclinical syndromes, and unknown.
Simona Lattanzi, Giada Giovannini, Niccolò Orlandi, Francesco Brigo, Eugen Trinka, Stefano Meletti   +5 more
wiley   +1 more source

Vagus nerve stimulation in super-refractory status epilepticus following hypoxic brain injury: a case report and review of the literature

Interdisciplinary Neurosurgery
Background: Status epilepticus (SE) is a life-threatening neurological condition that can be resistant to pharmacological treatments, particularly when triggered by severe brain insults such as asphyxia.
Farzan Fahim, Mahdi Mehmandoost, Faezeh Mousavinia, Amirmohammad Bahri, Negin Safari Dehnavi, Almirabbas Rouholamini, Omidreza Nikbakhtamirabad, Parisa Nikbakhtamirabad, Diba Akbarzadeh, Sayeh Oveisi, Yousef Moghadasi, Alireza Zali, Bijan Herfedoustbiazar   +12 more
doaj   +1 more source

Surgical treatment of focal symptomatic refractory status epilepticus with and without invasive EEG

Epilepsy and Behavior Case Reports, 2015
Purpose: Neurosurgery appears to be a reasonable alternative in carefully selected patients with refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE).
Carolina Cuello Oderiz, Marina Aberastury, Ana Gabriela Besocke, Jorge Sinner, Betiana Comas-Guerrero, Carlos Alberto Ciraolo, Maria Concepción Pasteris, Walter Horacio Silva, María del Carmen García   +8 more
doaj   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Frequency of anti‐neural antibodies and autoimmune epilepsy in focal epilepsy of unknown etiology: An observational study in a Singaporean cohort

Epilepsia Open, EarlyView.
Abstract Objective Autoimmune epilepsy (AES) is increasingly recognized as a condition in patients with epilepsy of unknown etiology. Early immunotherapy improves outcomes; however, data on its prevalence and the frequency of anti‐neural/neuronal antibodies in Asian populations remain scarce.
Seong Jin Park, Jeanne May May Tan, Xuejuan Peng, Patricia Yut Wan Wong, Karine Su Shan Tay, Angelia Swee Hoon Koe, Janis Siew Noi Tye, Josiah Yui Huei Chai, Pei Xuan Koh, Yee Leng Tan, Sheila Srinivasan, Ngai Kun Loh, Nigel Choon Kiat Tan, Kevin Tan, Tianrong Yeo   +14 more
wiley   +1 more source

Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus

Case Reports in Neurological Medicine, 2019
A 72-year-old man presented with a super-refractory partial status epilepticus following evacuation of a right subdural hematoma. He failed to respond to treatment with high doses of intravenous valproic acid, Levetiracetam, Lacosamide, Thiopental, and Midazolam.
Abdallah Rahbani, Grace Adwane, Najo Jomaa   +2 more
openaire   +3 more sources

p‐Brain: A Modular Open‐Source Framework for Automated Quantitative DCE‐MRI of Cerebral Perfusion, Microvasculature, and Blood–Brain Barrier Permeability

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT We present p‐Brain, a modular, open‐source framework for reproducible, automated quantitative DCE‐MRI at scale. Rather than a fixed pipeline, p‐Brain is built from interchangeable stages (ingestion, T1/M0$$ {T}_1/{M}_0 $$ fitting, vascular and tissue ROI extraction, signal‐to‐concentration conversion, kinetic modeling, and quality control ...
Edis D. Tireli, Stig P. Cramer, Ulrich Lindberg, Derya Tireli, Mark B. Vestergaard, Henrik B. W. Larsson   +5 more
wiley   +1 more source