Results 91 to 100 of about 1,493 (172)

Characteristics and long‐term outcomes of children with confirmed focal cortical dysplasia type 1 after epilepsy surgery: A population‐based study

Epilepsia Open, Volume 11, Issue 4, Page 1314-1328, August 2026.
Abstract Objective Focal cortical dysplasia type 1 (FCD1) is a rare and heterogeneous cause of drug‐resistant epilepsy (DRE) in children. Its clinical characteristics remain poorly understood, and surgical outcomes may be less favorable than in FCD2. We conducted a population‐based study to characterize the clinical presentation and long‐term seizure ...
Vincent Zheng, Päivi Koroknay‐Pál, Henri Lehtinen, Eija Gaily, Atte Karppinen, Anders Paetau, Olli Tynninen, Heta Leinonen, Aki Laakso, Eeva‐Liisa Metsähonkala   +9 more
wiley   +1 more source

Brexanolone, a First‐In‐Class Neurosteroid Medication: Mechanism of Action, Clinical, and Translational Science

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Given the increasing prevalence of postpartum depression (PPD) and the stigma associated with this condition, it is essential to address this significant health concern. Brexanolone is an FDA‐approved treatment for PPD that works by positive‐allosteric modulation of type A γ‐aminobutyric acid (GABAA) receptors.
Laura Gayanova, Katrina Sian, Jason Wells, Amber Fedin, YanFei Qi   +4 more
wiley   +1 more source

Stiripentol for the treatment of refractory status epilepticus

Neurological Research and Practice
Background Status epilepticus (SE) is one of the most common neurological emergencies and an acutely life-threatening condition characterized by high mortality and morbidity.
Leona Möller, Ole J. Simon, Clara Jünemann, Meike Austermann-Menche, Marc-Philipp Bergmann, Lena Habermehl, Katja Menzler, Lars Timmermann, Adam Strzelczyk, Susanne Knake   +9 more
doaj   +1 more source

Treatment of convulsive status epilepticus in Brazil: a review

Arquivos de Neuro-Psiquiatria
Status epilepticus (SE) is the most severe presentation of epilepsy. Currently, SE is defined according to 2 sequential time frames: time 1, after which it is unlikely that the seizure will resolve spontaneously, therefore requiring the initiation of ...
Luis Otavio Caboclo
doaj   +1 more source

Status Epilepticus: A Practical Guide for Intensivists

Türk Yoğun Bakim Derneği Dergisi
This review explores the pathophysiology of status epilepticus in adults, along with its incidence and key clinical considerations. We present a comprehensive treatment approach, emphasizing both emergent and urgent therapies.
Salia Farrokh, Ivanna Joseph
doaj   +1 more source

PROGRESSION FROM REFRACTORY STATUS EPILEPTICUS TO SUPER REFRACTORY STATUS EPILEPTICUS IN ICU ADMITTED PATIENTS

IBRO Neuroscience Reports, 2023
Dannys Rivero Rodríguez, Telmo Fernandez, Daniela Dicapua Sacoto, Yanelis Pernas Sanchez, María Isabel Morales-Casado, Graham Pluck   +5 more
doaj   +1 more source

Early initiation of intravenous cyclophosphamide and one‐year outcome in super‐refractory cryptogenic‐new onset refractory status epilepticus

Epilepsia Open
To explore the potential efficacy of early initiation of intravenous cyclophosphamide (IVCPA), we reviewed consecutive four cases of super‐refractory cryptogenic‐new onset refractory status epilepticus (C‐NORSE) between 2015 and 2023.
Yasufumi Yorichika, Shuichiro Neshige, Hideaki Sakahara, Narumi Ono, Megumi Nonaka, Yuichiro Tagane, Tomoaki Watanabe, Keisuke Tachiyama, Haruka Ishibashi, Masahiro Nakamori, Takeo Shishido, Shiro Aoki, Hiroki Ueno, Yu Yamazaki, Takahiro Iizuka, Hirofumi Maruyama   +15 more
doaj   +1 more source

Ketamine use for super-refractory status epilepticus in children [PDF]

Hong Kong Medical Journal, 2020
E L W, Fung, K M, Yam, M L Y, Yau
openaire   +2 more sources

Continuous Electroencephalography During and After Convulsive Status Epilepticus: Scope, Significance, and Standards

Annals of Indian Academy of Neurology
We report a case of super-refractory convulsive status epilepticus managed in our intensive care unit. Although the outcome was ultimately fatal, we present serial continuous electroencephalography (EEG) recordings obtained throughout this short but ...
Gagandeep Singh, Monika Singla, Birinder S Paul, Dhananjay Gupta   +3 more
doaj   +1 more source

Changes in lipids and inflammation in adults with super-refractory status epilepticus on a ketogenic diet. [PDF]

Front Mol Biosci, 2023
Dickens AM, Johnson TP, Lamichhane S, Kumar A, Pardo CA, Gutierrez EG, Haughey N, Cervenka MC.   +7 more
europepmc   +1 more source