Results 81 to 90 of about 1,493 (172)

Deletion of Astrocytic TNFR1 Attenuates Hyperexcitability and Initiation of Epileptogenesis

Glia, Volume 74, Issue 9, September 2026.
Inducible, astrocyte‐specific deletion of TNFR1 reduces basal EEG spectral power. Loss of astrocytic TNFR1 attenuates acute seizure activity in two distinct experimental models of epilepsy. Deletion of TNFR1 in astrocytes limits epilepsy development and hippocampal pathology in a mouse model of temporal lobe epilepsy with hippocampal sclerosis ...
Lukas Henning, Ioannis Zalachoras, Giovanni Carriero, Gerald Seifert, Peter Bedner, Christian Steinhäuser, Andrea Volterra   +6 more
wiley   +1 more source

Intensive care management of status epilepticus

Journal of Neuroanaesthesiology and Critical Care, 2016
Status epilepticus (SE) is a life-threatening neurological emergency that requires prompt diagnosis and treatment. SE may be classified into convulsive and non-convulsive types, based on the presence of rhythmic jerking of the extremities.
Nidhi Gupta
doaj   +1 more source

Distinct clinical clusters of paediatric patients with status epilepticus: Retrospective cohort study

Developmental Medicine &Child Neurology, Volume 68, Issue 9, Page 1305-1315, September 2026.
Large Swiss cohort of paediatric status epilepticus demonstrates that treatment delay (> 60 min) directly contributes to morbidity. Machine‐learning analysis of routine clinical data identifies three distinct patient clusters: febrile status epilepticus, severe para‐infectious status epilepticus, and status epilepticus in children with known epilepsy ...
Richard J Burman, Anne Steinberg, Jamie Norris, Giorgio Selmin, Tommaso Fedele, Richard E Rosch, Georgia Ramantani   +6 more
wiley   +1 more source

An international survey of the relatives and friends of electroconvulsive therapy recipients

Psychology and Psychotherapy: Theory, Research and Practice, Volume 99, Issue 3, Page 1013-1034, September 2026.
Abstract Objectives This study aimed to address the paucity of studies of the relatives and friends of electroconvulsive therapy (ECT) patients. Methods A total of 1144 people responded to an online survey. Results The respondents included 286 relatives and friends of ECT recipients, from 22 countries.
Christopher Harrop, Sue Cunliffe, Sarah Price Hancock, Lucy Johnstone, Lisa Morrison, John Read   +5 more
wiley   +1 more source

Do or Die: A Rapid‐Fire Tabletop Review of “Must Know” Emergency Medicine Pathologies

AEM Education and Training, Volume 10, Issue 4, August 2026.
ABSTRACT Background Emergency medicine (EM) physicians must rapidly recognize and manage time‐critical conditions; however, standardized methods to teach and assess competency in these scenarios remain limited and resource‐intensive. Objective To develop and implement a low‐resource, standardized tabletop simulation to evaluate EM residents' ability to
Jennifer Yee, Colin G. Kaide, Geremiha Emerson, Kelsey H. Jordan, Sorabh Khandelwal   +4 more
wiley   +1 more source

Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus

Epilepsy and Behavior Case Reports, 2018
We present the case of a child with long-standing, super-refractory status epilepticus (SRSE) who manifested prompt and complete resolution of SRSE upon exposure to pure cannabidiol.
Rajsekar R. Rajaraman, Raman Sankar, Shaun A. Hussain   +2 more
doaj   +1 more source

Genetic landscape of patients with atypical absence status epilepticus: A systematic review

Epilepsia Open, Volume 11, Issue 4, Page 1111-1125, August 2026.
Abstract Atypical absence status epilepticus (AASE) is a rare subtype of nonconvulsive status epilepticus (NCSE), characterized by clouding of consciousness and continuous or fluctuating epileptiform activity, generally at a frequency below 3 Hz. Only sparse literature exists on the genetic conditions associated with it.
Maria Cristina Cioclu, Giada Giovannini, Stefano Meletti   +2 more
wiley   +1 more source

Effectiveness and safety of implantable vagus nerve stimulation in people with primary generalized tonic–clonic seizures

Epilepsia Open, Volume 11, Issue 4, Page 1214-1226, August 2026.
The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston, Justine Curley, Ryan Verner, Maxine Dibue, Charles Gordon, Gaia Giannicola, Kathryn Nichol   +6 more
wiley   +1 more source

Supra-recommendation Treatment of Super-refractory Status Epilepticus

Journal of Epilepsy Research, 2016
A 28-year old female was admitted with recurrent seizures following 2 days of febrile illness, after which she developed status epilepticus. Midazolam and later thiopentone infusions were started after failure of regular intravenous antiepileptics.
Vyas, Devashish Dhiren, Dash, Gopal Krishna   +1 more
openaire   +2 more sources

Ketogenic diet therapy for children with super‐refractory status epilepticus in intensive care: International clinical practice recommendations

Epilepsia Open, Volume 11, Issue 4, Page 1354-1369, August 2026.
Abstract Objective We aimed to create practical recommendations to support healthcare teams starting ketogenic diet therapy (KDT) for children with super‐refractory status epilepticus in intensive care settings. Methods A literature review was conducted to extract published data on patient selection, diet prescription, diet initiation, monitoring, fine‐
Robyn Blackford, Victoria J. Whiteley, Isobel Hardy, Marisa Armeno, Tessa Bollard, J. Helen Cross, Christin Eltze, Susan George, Charlotte Howard, A. Laura Nijstad, Erin Talzzia, Chris Paget, Samiran Ray, Zoe Simpson, Elizabeth Song‐Pozderac, Agnieszka Szmurlo, Charlene Tan‐Smith, Lisa Vanatta, Elles van der Louw, Natasha E. Schoeler, on behalf of the Ketogenic Dietitians Research Network   +20 more
wiley   +1 more source