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Staphylococcus aureus: Superantigens and Autoimmunity
Staphylococcus aureus is one of the most prevalent pathogens in the human population. S. aureus exhibits several escape mechanisms that allow it to evade host defenses.
de Lourdes Ribeiro de Souza da Cunha, Maria [UNESP] +1 more
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IntroductionIt is currently unclear what the role of Group A streptococcus (GAS) virulence factors (VFs) is in contributing to the invasive potential of GAS.
Kimona Rampersadh +8 more
doaj +1 more source
Background and Objective: Streptococci are Gram-positive and anaerobic bacteria that are isolated from different sources. These bacteria are capable of producing superantigens, toxins, and biologically-active substances and are therefore very important ...
Kumarss Amini, Ali Habbadi
doaj
Staphylococcal superantigens (sAgs), such as toxic shock syndrome toxin 1 (TSST-1), induce massive cytokine production, which may result in toxic shock syndrome (TSS) and sepsis.
Norbert Stich +3 more
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Comparative genomics of vancomycin-resistant Staphylococcus aureus strains and their positions within the clade most commonly associated with methicillin-resistant S. aureus hospital-acquired infection in the United States [PDF]
This research was supported in part with federal funds from the NIAID/NIH/DHHS, including the Harvard-wide Program on Antibiotic Resistance (NIH grant AI083214), NIH grant EY017381 (M.S.G.), contract HHSN27220090018C, and the NARSA program supported ...
Griggs, Allison +34 more
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Human Group A Streptococci Virulence Genes in Bovine Group C Streptococci
Phage-encoded virulence genes of group A streptococci were detected in 10 (55.6%) of 18 isolates of group C streptococci that had caused bovine mastitis.
Márcia G. Rato +4 more
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The species Staphylococcus aureus harbors 19 superantigen gene loci, six of which are located in the enterotoxin gene cluster (egc). Although these egc superantigens are far more prevalent in clinical S.
Kohler, Christian +8 more
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Sleeping with the Enemy— Endogenous Superantigens in Humans [PDF]
We usually think of superantigens (SAg) as dangerous toxins that may cause toxic shock syndrome and death (Marrack and Kappler, 1990). Now, based on two papers in this issue of Immunity, it seems that we all have SAg genes within us, lying dormant and ...
Posnett, David N, Yarilina, Anna A
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Superantigens and nasal polyps
Nasal polyps represent an often severe T-cell-orchestrated eosinophilic upper airway disease with currently unknown pathogenesis, often associated with lower airway disease, such as asthma. Superantigens, predominantly derived from Staphylococcus aureus,
Van Cauwenberge, Paul +9 more
core +1 more source

