Results 91 to 100 of about 13,743 (223)

The Antistaphylococcal Activity of Citropin 1.1 and Temporin A against Planktonic Cells and Biofilms Formed by Isolates from Patients with Atopic Dermatitis: An Assessment of Their Potential to Induce Microbial Resistance Compared to Conventional Antimicrobials

Pharmaceuticals, 2016
Staphylococcus aureus (SA) colonizes the vast majority of patients with atopic dermatitis (AD). Its resistance to antibiotics and ability to form biofilms are the main origins of therapeutic complications. Endogenous antimicrobial peptides (AMPs) exhibit
Malgorzata Dawgul, Wioletta Baranska-Rybak, Lidia Piechowicz, Marta Bauer, Damian Neubauer, Roman Nowicki, Wojciech Kamysz   +6 more
doaj   +1 more source

egc Superantigens Impair Monocytes/Macrophages Inducing Cell Death and Inefficient Activation

Frontiers in Immunology, 2020
Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, causing immunosuppression, and ...
Sofia Noli Truant, Sofia Noli Truant, Mauricio C. De Marzi, Mauricio C. De Marzi, Mauricio C. De Marzi, Mauricio C. De Marzi, María B. Sarratea, María B. Sarratea, María B. Antonoglou, María B. Antonoglou, Ana P. Meo, Laura V. Iannantuono López, Laura V. Iannantuono López, María J. Fernández Lynch, María J. Fernández Lynch, Marcos Todone, Marcos Todone, Marcos Todone, Emilio L. Malchiodi, Emilio L. Malchiodi, Marisa M. Fernández, Marisa M. Fernández   +21 more
doaj   +1 more source

Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions

MedComm, Volume 7, Issue 3, March 2026.
Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song, Yazhi Mo, Si Chen, Yuemei Chen, Chunying Zhang, Shanying Deng, Juan Liao, Yi He, Wei Wang, Weidong Zheng, Tingting Zeng   +10 more
wiley   +1 more source

Rhinosinusitis derived Staphylococcal enterotoxin B plays a possible role in pathogenesis of food allergy [PDF]

, 2006
Background Staphylococcal enterotoxin B (SEB) is a potent immunomodulator and implicated with pathogenesis of inflammatory diseases mediated by Th1 or Th2 dominant immune responses.
Tao Liu, Bin-Quan Wang, Peng-Yuan Zheng, Shao-Heng He, Ping-Chang Yang, AD Moneret-Vautrin, VR Baral, J Grundy, H Vliagoftis, N Kalach, DY Leung, B Fleischer, A Nomizo, C Bachert, M Okano, HS Lehmann, PC Yang, LK Poulsen, MD Regueiro, T Frisch, R Riffon, PC Yang, LK Wilcock, J Hsu, M Remer, BA Senior, HS Lehmann, J Fernandes, JP Corey, N Zhang, K Crossley, P Lionetti, E Lindberg, J Fraser, PC Yang, JV Saarinen, U Seitzer, K Adel-Patient, O Keskin, G Arad, JJ Bright, JA Dunstan, JH Lee, EC de Jong, HZ Shi, T Shiomori, Y Kawabe   +46 more
core   +1 more source

The microbiome in patients with atopic dermatitis. [PDF]

, 2019
As an interface with the environment, the skin is a complex ecosystem colonized by many microorganisms that coexist in an established balance. The cutaneous microbiome inhibits colonization with pathogens, such as Staphylococcus aureus, and is a crucial ...
Gallo, Richard L, Irvine, Alan D, Kong, Heidi H, Luger, Thomas, Naik, Shruti, Paller, Amy S, Scharschmidt, Tiffany C, Seed, Patrick   +7 more
core  

EXPRESSION OF A FUNCTIONAL CHIMERIC lg-MHC CLASS II PROTEIN [PDF]

, 1992
composed of the a- and ß-chains of the MHC class I1 I-E molecule fused to antibody V regions derived from anti-human CD4 mAb MT310. Expression vectors were constructed containing the functional, rearranged gene segments coding for the V region domains of
Becker, Andrea, Karlsson, Lars, Peterson, Per A., Rieber, Ernst Peter, Riethmüller, Gert, Weiss, Elisabeth H., Weissenhorn, Winfried, Widera, Georg, Zwirner, Jörg   +8 more
core   +1 more source

Causes of Kawasaki Disease—From Past to Present

Frontiers in Pediatrics, 2019
Kawasaki disease (KD) is a multisystem vasculitis that primarily affects the coronary arteries of young children. The causes of KD remain a mystery. It is suspected that some sort of infectious agent is involved because KD has epidemicity and seasonality.
Satoru Nagata
doaj   +1 more source

Epidemiological and Molecular Characterization of an Invasive Group A Streptococcus32.2 Outbreak [PDF]

, 2017
Anemm32.2 invasive group A streptococcus (iGAS) outbreak occurred in Liverpool from January 2010 to September 2012. This genotype had not previously been identified in Liverpool, but was responsible for 32% (14/44) of all iGAS cases reported during this ...
Alaearts, Maaike, Alsahag, Mansoor, Anson, James, Bevan, Edward, Bricio Moreno, Laura, Clarke, Jenny, Cornick, Jennifer E, Everett, Dean B, French, Neil, Jenkinson, Howard F, Kadiolgu, Aras, Kiran, Anmol M, Nobbs, Angela H, Van Aartsen, Jon, Vivancos, Roberto   +14 more
core   +5 more sources

Host-pathogen interactions in invasive Staphylococcus aureus infections [PDF]

, 2016
Staphylococcus aureus is a versatile human pathogen causing a wide range of diseases from uncomplicated skin and soft tissue infections to life-threatening invasive diseases like endocarditis, bacteremia, necrotizing pneumonia, and fasciitis.
Mairpady Shambat, Srikanth
core   +1 more source

Isolation, Cloning, and Expression of Streptococcus dysgalactiae Subspecies Superantigen by SDS-PAGE in Psoriasis Patients

مجله دانشگاه علوم پزشکی گرگان, 2022
Background and Objective: Streptococci are Gram-positive and anaerobic bacteria that are isolated from different sources. These bacteria are capable of producing superantigens, toxins, and biologically-active substances and are therefore very important ...
Kumarss Amini, Ali Habbadi
doaj