Results 171 to 180 of about 533,516 (306)

Antagonist Targeting the Species‐Specific Fatty Acid Dehydrogenase/Isomerase FabX for Anti‐H. pylori Infection

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang   +9 more
wiley   +1 more source

RNAlater facilitates remote sampling of aquaculture Atlantic salmon liver for proteomic analysis

open access: yesAquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 578-586, December 2022., 2022
Graphical Abstract Proteomes of similar sizes were obtained in samples preserved by snap‐freezing or RNAlater. Proteins involved in transcriptional and translational machinery were affected in RNAlater stored samples. Abundance of published markers for heat and oxidative stress was not affected by snap‐freezing or RNAlater.
Anca G. Rusu   +6 more
wiley   +1 more source

Molecular Principles of Proton-Coupled Quinone Reduction in the Membrane-Bound Superoxide Oxidase. [PDF]

open access: yesJ Am Chem Soc
Riepl D   +7 more
europepmc   +1 more source

Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling

open access: yesAdvanced Science, EarlyView.
A vessel‐on‐a‐chip system is developed to replicate both physiological and pathological vessel cyclic stretches. Proteomic analysis reveals pressure‐overload‐induced vascular remodeling, including cellular response to mechanical cues, cellular oxidative stresses, ER stress, and ceramide biosynthesis activation in the vessel‐on‐a‐chip system, well ...
Yanjun Liu   +11 more
wiley   +1 more source

Enhancement of platelet function by superoxide anion. [PDF]

open access: bronze, 1977
Robert I. Handin   +2 more
openalex   +1 more source

Mitigating Doxorubicin‐Induced Cardiotoxicity and Enhancing Anti‐Tumor Efficacy with a Metformin‐Integrated Self‐Assembled Nanomedicine

open access: yesAdvanced Science, EarlyView.
A novel self‐assembled nanomedicine (PMDDH) has been developed for the co‐delivery of doxorubicin and metformin, aiming to enhance the anti‐tumor efficacy of doxorubicin while alleviating its cardiotoxicity through the activation of cGAS‐STING and AMPK signaling pathways, respectively.
Jiaxin Huang   +9 more
wiley   +1 more source

Ion−π interactions for constructing organic luminescent materials

open access: yesAggregate, Volume 3, Issue 6, December 2022., 2022
The construction of organic fluorescence and room temperature phosphorescence materials by using ion−π interactions including anion−π interactions and cation−π interactions is presented in this minireview. The applications of these ion−π type organic luminescent materials in bioimaging, imaging‐guided anticancer, and antibacterial treatment are also ...
Guoyu Jiang   +3 more
wiley   +1 more source

Reaction of superoxide radicals with glycosaminoglycan chloramides: a kinetic study. [PDF]

open access: yes, 2013
A.W.J. Paterson   +57 more
core   +1 more source

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