Results 231 to 240 of about 315,385 (314)

Neuronal FGF13 Inhibits Mitochondria‐Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song   +15 more
wiley   +1 more source

Cu7S4 Nanozyme Efficiently Inactivating Drug‐Resistant Bacteria on Mouse Wound Models through Photodynamic and Photothermal Synergetic Therapy

open access: yesAdvanced Science, EarlyView.
Cu7S4 nanozymes, exhibiting peroxidase‐like, catalase‐like, and GSH‐depletion activities, are synthesized through defect engineering. These nanozymes demonstrate rapid inactivation of Gram‐negative bacteria, including Escherichia coli and Pseudomonas aeruginosa. In a mouse skin wound model infected with P. aeruginosa, the nanozyme showcases exceptional
Xueya Li   +15 more
wiley   +1 more source

SOD1 Protein Content in Human Central Nervous System and Peripheral Tissues. [PDF]

open access: yesJ Neurochem
Leykam L   +6 more
europepmc   +1 more source

Revealing the Mechanism of Exciton Spontaneous Separation at Room Temperature for Efficient Photocatalytic Hydrogen Peroxide Synthesis

open access: yesAdvanced Science, EarlyView.
This study identifies that replacing electron‐donating units at different positions enhances the delocalization of the electron cloud in the electron donors, which in turn increases the delocalization of the overall material. The exciton activation energy is effectively reduced, promoting the spontaneous dissociation of excitons at room temperature and
Pan Jiang   +9 more
wiley   +1 more source

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

open access: yesAdvanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu   +14 more
wiley   +1 more source

Radiation Effects on Uranyl Tetrachloro Coordination Compounds: Impact of Lattice Water. [PDF]

open access: yesInorg Chem
Rajapaksha H   +4 more
europepmc   +1 more source

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

open access: yesAdvanced Science, EarlyView.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves   +17 more
wiley   +1 more source

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