Results 251 to 260 of about 442,139 (308)

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

Enviromics and Abiotic Enviromics: Enhancing Stress Biology and Plant Resilience Breeding

open access: yesAdvanced Science, EarlyView.
Environmental stressors are captured through high‐throughput envirotyping and integrated into an enviromic framework with genomic, transcriptomic, phenomic, and environmental data. AI/ML models enable prediction and guide marker‐assisted selection, genomic selection, genome editing, and gene pyramiding toward improved abiotic stress tolerance, yield ...
Guangchao Sun   +6 more
wiley   +1 more source

Two-electron mediation enables fast alkali peroxide cycling and suppresses side reactions in metal-O2 cells

open access: yes
Freunberger S   +15 more
europepmc   +1 more source

Priming of human monocytes by β-glucan and obesity-associated factors: modifications to global DNA methylation, gene expression, phenotype and function. [PDF]

open access: yesFront Immunol
Topham BJ   +8 more
europepmc   +1 more source

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