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Impact of the spatial distribution of positive charges on the catalytic activity of NiSOD bioinspired complexes. [PDF]
Guinard P +5 more
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Semaglutide and Liraglutide Modulate Oxidative Stress and Wound Repair in Normal Human Skin Cells Exposed to an In Vitro Diabetic-like Environment. [PDF]
Anastasiou IA +6 more
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The Reaction of no With Superoxide
Free Radical Research Communications, 1993The rate constant for the reaction of NO with .O2- was determined to be (6.7 +/- 0.9) x 10(9) l mol-1 s-1, considerably higher than previously reported. Rate measurements were made from pH 5.6 to 12.5 both by monitoring the loss of .O2- and the formation of the product -OONO.
Robert E Huie, S Padmaja
exaly +3 more sources
Pulmonary Pharmacology and Therapeutics, 2002
In this review we describe the potential role(s) of superoxide in inflammatory disorders.
Salvatore Cuzzocrea, Carolina Muscoli
exaly +4 more sources
In this review we describe the potential role(s) of superoxide in inflammatory disorders.
Salvatore Cuzzocrea, Carolina Muscoli
exaly +4 more sources
Superoxide, Superoxide Dismutase and the Respiratory Burst
Veterinary Clinical Pathology, 1983SummaryPhagocytes undergo a sharp burst of oxygen consumption when engulfing bacteria. This oxygen is enzymatically reduced to toxic metabolites which are essential to the bactericidal action of the cell. Oxygen metabolites formed in this burst as well as other intermediates formed in biological reduction reactions do not selectively reserve their ...
H S, Bender, W R, Chickering
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SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES
Annual Review of Biochemistry, 1972O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity, may peroxidize spin trapping agents and thus give the appearance of catalyzing OH ...
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The Journal of Physical Chemistry B, 2005
Density-functional calculations indicate that the second sphere of coordination around the metal centers of manganese and iron superoxide dismutases (MnSODs and FeSODs) plays an important role in the binding of O2(-). In these systems, O2(-) prefers to bind to Mn or Fe in end-on configurations. For human and E.
Isabel A, Abreu +2 more
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Density-functional calculations indicate that the second sphere of coordination around the metal centers of manganese and iron superoxide dismutases (MnSODs and FeSODs) plays an important role in the binding of O2(-). In these systems, O2(-) prefers to bind to Mn or Fe in end-on configurations. For human and E.
Isabel A, Abreu +2 more
openaire +2 more sources
Parasitology Today, 1994
Eric James here discusses the molecular forms of superoxide dismutase and looks at its potential role in the pathogenesis of parasitic infections.
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Eric James here discusses the molecular forms of superoxide dismutase and looks at its potential role in the pathogenesis of parasitic infections.
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Engineered Superoxide Dismutase Monomers for Superoxide Biosensor Applications
Analytical Chemistry, 2005Because of its high reaction rate and specificity, the enzyme superoxide dismutase (SOD) offers great potential for the sensitive quantification of superoxide radicals in electrochemical biosensors. In this work, monomeric mutants of human Cu,Zn-SOD were engineered to contain one or two additional cysteine residues, which could be used to bind the ...
Beissenhirtz, Moritz Karl +3 more
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