Superoxide Anion Chemistry—Its Role at the Core of the Innate Immunity
Classically, superoxide anion O2•− and reactive oxygen species ROS play a dual role. At the physiological balance level, they are a by-product of O2 reduction, necessary for cell signalling, and at the pathological level they are considered harmful, as ...
Celia María Curieses Andrés +4 more
semanticscholar +1 more source
Background: Chronic renal failure, particularly end-stage renal disease, is a serious health problem associated with a high mortality rate. Uremic syndrome leads to increased oxidative stress, inflammation, and dyslipidemia.
Ana Ninić +9 more
doaj +1 more source
Amperometric enzyme sensor to check the total antioxidant capacity of several mixed berries. comparison with two other spectrophotometric and fluorimetric methods [PDF]
The aim of this research was to test the correctness of response of a superoxide dismutase amperometric biosensor used for the purpose of measuring and ranking the total antioxidant capacity of several systematically analysed mixed berries.
CAMPANELLA, Luigi +4 more
core +2 more sources
Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic
Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing superoxide breakdown and is important for most forms of eukaryotic life.
B. G. Trist +4 more
semanticscholar +1 more source
Cu,Zn superoxide dismutase genes in Tribolium castaneum: evolution, molecular characterisation and gene expression during immune priming. [PDF]
The production of reactive oxygen species (ROS) is a normal consequence of the aerobic cell metabolism. Despite their high and potentially detrimental reactivity with various biomolecules, the endogenous production of ROS is a vital part of physiological,
Bakiu, Rigers +5 more
core +2 more sources
Manganese Superoxide Dismutase Dysfunction and the Pathogenesis of Kidney Disease
The mitochondria are a major source of reactive oxygen species (ROS). Superoxide anion (O2•–) is produced by the process of oxidative phosphorylation associated with glucose, amino acid, and fatty acid metabolism, resulting in the production of adenosine
Munehiro Kitada +4 more
semanticscholar +1 more source
Copper toxicity in soil was evaluated using biomarkers of oxidative stress (catalase enzyme activity, superoxide dismutase and lipid peroxidation) in the earthworm Eisenia foetida. Agricultural topsoils from mining areas of the Aconcagua river basin were
Hernán Gaete +3 more
doaj +1 more source
Literature-based discovery of diabetes- and ROS-related targets [PDF]
Background Reactive oxygen species (ROS) are known mediators of cellular damage in multiple diseases including diabetic complications. Despite its importance, no comprehensive database is currently available for the genes associated with ROS.
A Erol +54 more
core +5 more sources
Manganese Superoxide Dismutase Overexpression Attenuates MPTP Toxicity
There is substantial evidence implicating mitochondrial dysfunction and free radical generation in the neurotoxicity of MPTP. Manganese superoxide dismutase (MnSOD) is the primary antioxidant enzyme protecting against superoxide radicals produced within ...
Peter Klivenyi +6 more
doaj +1 more source
Catalase, glutathione peroxidase, metabolic syndrome, superoxide dismutase
Labor pain is part of a normal process, which often causes physiological and psychological stress to mother. These stress have impact to both mother and fetus. Largely (90%) labor comes with pain and in some cases severe pain.
Tarsikah +2 more
doaj +1 more source

