Influence of hyperhomocysteinemia on the cellular redox state - Impact on homocysteine-induced endothelial dysfunction [PDF]
Hyperhomocysteinemia is an independent risk factor for the development of atherosclerosis. An increasing body of evidence has implicated oxidative stress as being contributory to homocysteines deleterious effects on the vasculature.
Keaney, John F. +5 more
core +1 more source
Background: Chronic renal failure, particularly end-stage renal disease, is a serious health problem associated with a high mortality rate. Uremic syndrome leads to increased oxidative stress, inflammation, and dyslipidemia.
Ana Ninić +9 more
doaj +1 more source
Enhanced mitochondrial superoxide scavenging does not Improve muscle insulin action in the high fat-fed mouse [PDF]
Improving mitochondrial oxidant scavenging may be a viable strategy for the treatment of insulin resistance and diabetes. Mice overexpressing the mitochondrial matrix isoform of superoxide dismutase (sod2tg mice) and/or transgenically expressing catalase
Jeffrey S. Bonner¤b +30 more
core +2 more sources
Manganese Superoxide Dismutase Overexpression Attenuates MPTP Toxicity
There is substantial evidence implicating mitochondrial dysfunction and free radical generation in the neurotoxicity of MPTP. Manganese superoxide dismutase (MnSOD) is the primary antioxidant enzyme protecting against superoxide radicals produced within ...
Peter Klivenyi +6 more
doaj +1 more source
Signaling pathways and mechanism of action of the extracellular superoxide dismutase, SOD3 [PDF]
Reactive oxygen species (ROS) and especially hydrogen peroxide (H2O2) have been implicated in a multitude of cellular events ranging from pathogen eradication to finely tuned intracellular signal transduction under normal and pathological conditions.
Laatikainen, Lilja Elisa
core +1 more source
Catalase, glutathione peroxidase, metabolic syndrome, superoxide dismutase
Labor pain is part of a normal process, which often causes physiological and psychological stress to mother. These stress have impact to both mother and fetus. Largely (90%) labor comes with pain and in some cases severe pain.
Tarsikah +2 more
doaj +1 more source
The trail to superoxide dismutase [PDF]
City College of New York + Cornell Medical School + Duke. While a youngster, I was enthralled by the miracle of insect metamorphosis and followed the transformations of pet caterpillars to pupae and then to gloriously beautiful butterflies and moths. This led naturally to an interest in biology. but mere description was not totally satisfying.
openaire +2 more sources
Characterising the Drosophila extracellular superoxide Dismutase gene
The indiscriminate action of reactive oxygen species (ROS), if left unregulated, haslong been considered contributory to a range of disease processes within the animalkingdom and is also a factor associated with ageing.
Blackney, Michael James
core +2 more sources
OBJECTIVES: Our previous study demonstrated that superoxide dismutase levels were higher in tuberculous pleural effusions than in malignant pleural effusions, but that this difference ...
Maoshui Wang +2 more
doaj +1 more source
Changes in expression of manganese superoxide dismutase, copper and zinc superoxide dismutase and catalase in Brachionus calyciflorus during the aging process. [PDF]
Rotifers are useful model organisms for aging research, owing to their small body size (0.1-1 mm), short lifespan (6-14 days) and the relative easy in which aging and senescence phenotypes can be measured.
Jianghua Yang +5 more
doaj +1 more source

