Results 31 to 40 of about 349,476 (296)

Superoxide dismutase and neurological disorders

IBRO Neuroscience Reports
Superoxide dismutase (SOD) is a common antioxidant enzyme found majorly in living cells. The main physiological role of SOD is detoxification and maintain the redox balance, acts as a first line of defence against Reactive nitrogen species (RNS ...
Saravana Babu Chidambaram, Nikhilesh Anand, Sudhir Rama Varma, Srinivasan Ramamurthy, Chandrasekaran Vichitra, Ambika Sharma, Arehally M. Mahalakshmi, Musthafa Mohamed Essa   +7 more
doaj   +1 more source

The Copper Chaperone for Superoxide Dismutase [PDF]

Journal of Biological Chemistry, 1997
Copper is distributed to distinct localizations in the cell through diverse pathways. We demonstrate here that the delivery of copper to copper/zinc superoxide dismutase (SOD1) is mediated through a soluble factor identified as Saccharomyces cerevisiae LYS7 and human CCS (copper chaperone for SOD).
Cizewski Culotta, V., Klomp, L.W.J., Strain, J., Casareno, R.L.B., Krems, B., Gitlin, J.D.   +5 more
openaire   +3 more sources

Superoxide dismutase participation in plant adaptation to herbicides

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2005
Antioxidative enzyme superoxide dismutase (SOD) role in maize grain was investigated under herbicide action. Combinations of Dialen C with Harness, Primextra Gold and Frontier were used. Increasing in SOD activity proved to be a highly sensitive reaction.
A. S. Rossikhina, O. M. Vinnychenko
doaj   +1 more source

Superoxide and superoxide dismutase in pulmonary hypoxic vasoconstriction [PDF]

, 2002
Superoxide is known to cause vascular damage and can consume protective NO that maintains a low pulmonary pressure. There is evidence suggesting that hypoxia upregulates NADH/NADPH oxidase and xanthine oxidase in the smooth muscle and endothelial cells ...
Wadsworth, R.M., Milliken, P.H.
core   +4 more sources

Pergolide can induce soluble Superoxide dismutase in rat striata

, 1992
Pergolide, a dopamine receptor agonist, given daily i.p. for three weeks at 0.04mg/kg and 0.4mg/kg, significantly induced soluble (Cu-Zn) superoxide dismutase in the rat striatum, while having no effect on the mitochondrial (Mn) form of the enzyme.
Hussain, T., Glover, V., Sandler, M., Clow, A., Walker, M., Dexter, D.   +5 more
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

(−)-Deprenyl can induce soluble superoxide dismutase in rat striata

, 1991
(–)-Deprenyl (0.25 or 2mg/kg) or saline was injected daily into male Wistar rats for 3 weeks. The striata were dissected out and soluble and particulate Superoxide dismutase activity measured.
Hussain, T., Glover, V., Sandler, M., Clow, A., Walker, M., Dexter, D.   +5 more
core   +1 more source

A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice [PDF]

, 2005
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition characterized by motoneuron degeneration and muscle paralysis. Although the precise pathogenesis of ALS remains unclear, mutations in Cu/Zn superoxide dismutase (SOD1) account for
Dairin Kieran, Martin, J, Joanne Martin, Schiavo, G, Giampietro Schiavo (107907), Dick, JRT, Greensmith, L., Joanne Martin (11260388), Bohnert, S, Hafezparast, M., Elizabeth M.C. Fisher, Fisher, EMC, Linda Greensmith, Stephanie Bohnert (16066082), Martin, J., Majid Hafezparast (4461484), Fisher, E.M.C., James R T Dick (16066085), Majid Hafezparast, Greensmith, L, Linda Greensmith (252146), Giampietro Schiavo, Kieran, D., Bohnert, S., Stephanie Bohnert, James R.T. Dick, Dairin Kieran (7953794), Dick, J.R.T., Kieran, D, Hafezparast, M, Schiavo, G., Elizabeth M C Fisher (16062626)   +31 more
core   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

Polymeric membranes with selective permeability : shielding of an antioxidant enzyme [PDF]

, 2008
In this work we designed an antioxidant nanoreactor based on the encapsulation of CuZnSOD in amphiphilic copolymer nanovesicles. The nanovesicles are formed by self-assembly of amphiphilic copolymer poly-(2-methyloxazoline)-poly- (dimethylsiloxane ...
Axthelm, Fabian
core   +1 more source