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A Review of the Catalytic Mechanism of Human Manganese Superoxide Dismutase
Superoxide dismutases (SODs) are necessary antioxidant enzymes that protect cells from reactive oxygen species (ROS). Decreased levels of SODs or mutations that affect their catalytic activity have serious phenotypic consequences.
J. Azadmanesh, G. Borgstahl
semanticscholar +1 more source
Objective: The objective of the study was to compare the salivary Superoxide dismutase (mU/L) level among stage one patients of Oral sub mucous fibrosis and healthy controls.
Humera Akhlaq+2 more
doaj +1 more source
Genetics of human superoxide dismutase [PDF]
The formal genetics of superoxide dismutase has been studied in a family material from northern Sweden. The results verify the hypothesis that the three phenotypes SOD 1, SOD 2–1 and SOD 2 are controlled by two autosomal alleles. Although the SOD2 gene appears to be associated with somewhat lower enzyme activity, the SOD 2–1 and SOD 2 types were found ...
Gunhild Beckman+2 more
openaire +3 more sources
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Methylglyoxal interaction with superoxide dismutase 1
Methylglyoxal (MG) is a highly reactive aldehyde spontaneously formed in human cells mainly as a by-product of glycolysis. Such endogenous metabolite reacts with proteins, nucleotides and lipids forming advanced glycation end-products (AGEs). MG binds to
Panagis Polykretis+3 more
doaj
To determine the influence of smoking on blood and salivary superoxide dismutase enzyme levels among smokers, and to demonstrate the significant alterations in the levels of superoxide dismutase in association with patient age, periodontal disease status,
Haziel Diana Jenifer+4 more
doaj +1 more source
Scanning Electron Microscopy and Metabolite Measurement Revealed the Stress Mechanism of PS-COOH Microplastics on Rhodotorula mucilaginosa AN5 [PDF]
Microplastics in the marine environment have been paid more and more attention by researchers, and the impact of these substances on marine microorganisms can not be ignored. Studies have shown that PS-COOH Microplastics are harmful to marine molluscs, algae and monads.
arxiv
Superoxide Dismutase Mimics [PDF]
Dear Editor: We write to correct some of the misleading descriptions of our research in a Comprehensive Invited Review “Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential” by Dr. Ines Batinic-Haberle and colleagues (1). We wish to correct two factual errors and then discuss a matter of opinion.
Rosalind A. Rosenthal+2 more
openaire +2 more sources
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses [PDF]
The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model. Both metallic copper and copper oxide nanoparticles have been tested, with copper ion and zirconium oxide nanoparticles used as controls.
arxiv +1 more source