Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent [PDF]
A recombinant MnSOD (rMnSOD) synthesized by specific cDNA clones derived from a liposarcoma cell line was shown to have the same sequence as the wild-type MnSOD expressed in the human myeloid leukaemia cell line U937, except for the presence of the ...
A. BORRELLI+17 more
core +2 more sources
Determination of Some Antioxidan Enzyme Activities in Fresh and Dry Grapes (Vitis vinifera L.)
INTRODUCTION: Phenolic compounds in fruits and vegetables are very important in terms of eliminating free radicals. Most phenolic compounds are known to have antioxidant activity and can help protect cells against oxidative damage caused by free radicals.
Halit Demir, Ayhan GÜLER, Canan Demir
doaj +1 more source
Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19? [PDF]
Human lungs single cell RNA sequencing data from healthy donors (elderly and young; GEO accession number GSE122960) were analyzed to isolate and specifically study gene expression in alveolar type II cells.
Abouhashem, Ahmed S.+3 more
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Superoxide Dismutase (SOD)-mimetic M40403 is protective in cell and fly models of paraquat toxicity: Implications for Parkinson disease [PDF]
Parkinson disease is a debilitating and incurable neurodegenerative disorder affecting 3c1-2% of people over 65 years of age. Oxidative damage is considered to play a central role in the progression of Parkinson disease and strong evidence links chronic
Beltramini, Mariano+8 more
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Functional and structural mimics of superoxide dismutase enzymes [PDF]
Superoxide dismutase (SOD) enzymes form important defence line in living organisms. Through a dismutation reaction they transform the highly reactive superoxide radical ion to oxygen and hydrogen peroxide.
Pálinkó, István
core
Mouse models for preeclampsia: disruption of redox-regulated signaling [PDF]
The concept that oxidative stress contributes to the development of human preeclampsia has never been tested in genetically-defined animal models. Homozygous deletion of catechol-Omethyl transferase (Comt-/-) in pregnant mice leads to human preeclampsia ...
A Malassine+51 more
core +4 more sources
Introduction Antioxidant enzymes protect the human body against the harmful effects of oxidative stress. The activity of antioxidant enzymes changes with age and depends on dietary nutrients such as fats and vitamins, which can have a significant impact ...
Elżbieta Cecerska-Heryć+9 more
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Protective effect of (-) α-bisabolol on markers of oxidative stress in erythrocytes subjected to oxidative insult [PDF]
(-)-α-bisabolol is a sesquiterpene alcohol found as a major component of essential oil of chamomile (Matricaria recutita L., Chamomilla recutita L., Matricaria chamomilla L.; Family Asteraceae).
Suaib Luqman, Suchita Srivastava
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The effectiveness of perftoran and recombinant superoxide dismutase in complex post-operative therapy in patients with acute intestinal obstruction was investigated. All patients (two groups) were combined.
D. V. Volkov+3 more
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Superoxide Dismutase: A Biomarker for Early Diagnosis of Tuberculosis [PDF]
Introduction: Tuberculosis (TB) is a major public health concern in developing countries. Traditional diagnostic methods such as microscopic detection of organism and histopathological examination are limited in their capacity to provide information on ...
Dipak Kumar Chattopadhyay
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