Results 121 to 130 of about 10,242 (303)
Advanced Science, EarlyView.Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang +8 more
wiley +1 more source
, 2013 Parkinson's disease is characterized by dopamine cell loss of the substantia nigra. Parkinson's disease and the neurotoxin 1-methyl-4-phenyl-1,2,5,6 tetrahydropyridine may destroy dopamine neurons through oxidative stress.
Roth, Robert H. +12 more
core +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Free radicals in the aqueous humor of patients with glaucoma
Clinical Ophthalmology, 2010 Eiki Oshida, Yukihiro Matsumoto, Kiyomi Arai1Department of Ophthalmology, Dokkyo Medical University Koshigaya Hospital, Koshigaya, Saitama, JapanPurpose: To clarify the presence of oxidative stress in glaucoma and discuss whether free radicals contribute
Eiki Oshida +2 more
doaj
Novel Computational Methods for Studying Charge Transport in Metal-air Batteries [PDF]
, 2019 The process of electrifying transportation is progressing slowly and the development is mainly carried by the application of Li-ion batteries. Metal-airbatteries are a class of batteries that have the potential to outperform Li-ionbatteries on many key ...
Mathiesen, Nicolai Rask
core
Advanced Science, EarlyView.We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source
Applied Catalysis O: OpenThe increasing demand for a low cost and sustainable technology towards the production of reactive oxidants for water treatment continues to draw the attention of researchers.
Babatunde A. Koiki, Omotayo A. Arotiba
doaj +1 more source
Advanced Science, EarlyView.Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu +10 more
wiley +1 more source
Role of the polymorphonuclear neutrophils in the phototoxic reaction in porphyria cutanea tarda
, 1985 We have compared the superoxide production of polymorphonuclear cells (PMNLs) from healthy donors, when incubated with either control or porphyria cutanea tarda (PCT) sera at 4, 24 and 48 hours after exposure in vivo to UVA light.
L. Brambilla +5 more
core
Advanced Science, EarlyView.We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi +15 more
wiley +1 more source