Results 311 to 320 of about 49,276 (355)
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Superoxide interaction with nickel and iron superoxide dismutases
Journal of Molecular Graphics and Modelling, 2009Interaction of superoxide with the metal active sites of nickel and iron-containing superoxide dismutases is investigated with density functional theory. Outer-sphere mechanisms for both the reduction and oxidation of superoxide are proposed to be the common feature of these structurally unrelated SODs.
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Pulmonary Pharmacology & Therapeutics, 2002
In this review we describe the potential role(s) of superoxide in inflammatory disorders.
SALVEMINI D +3 more
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In this review we describe the potential role(s) of superoxide in inflammatory disorders.
SALVEMINI D +3 more
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Superoxide in the pulmonary circulation
Pharmacology & Therapeutics, 1999Superoxide formation in pulmonary tissue is modulated by cytokines, PO2, shear force, and disease states, and can be stimulated by drugs. Superoxide has diverse actions on pulmonary cells, including smooth muscle contraction, interaction with redox enzymes, cell proliferation, and gene transcription.
Wadsworth, RM, Demiryurek, AT
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SUPEROXIDE RADICALS, SUPEROXIDE DISMUTASES AND THE AEROBIC LIFESTYLE
Photochemistry and Photobiology, 1978Abstract— The superoxide radical (O‐2) is a commonplace product of the biological reduction of molecular oxygen and plays an important role in oxygen toxicity. Superoxide dismutases (SOD) catalytically scavenge this radical and are the primary defense against its cytotoxicity. The data which support these statements have been briefly reviewed.
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Development of a superoxide sensor by immobilization of superoxide dismutase
Sensors and Actuators B: Chemical, 2002Abstract Superoxide (O 2 − , one of the reactive oxygen species (ROS)) produced in vivo plays various pathphysiological and physiological roles, and thus it is of great importance and value to evaluate quantitatively dynamic changes in superoxide concentration. We thus aimed at developing a superoxide dismutase (SOD)-immobilized sensor.
Naoyuki Himi +7 more
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Parasitology Today, 1994
Eric James here discusses the molecular forms of superoxide dismutase and looks at its potential role in the pathogenesis of parasitic infections.
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Eric James here discusses the molecular forms of superoxide dismutase and looks at its potential role in the pathogenesis of parasitic infections.
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The Reaction of S-Nitrosoglutathione with Superoxide
Biochemical and Biophysical Research Communications, 1998The nitric oxide (NO)-dependent S-nitrosation of thiols to generate S-nitrosothiols has been proposed as an important pathway for the metabolism of NO in vivo. Although it has been suggested that these S-nitrosated compounds are resistant to decomposition by reactive oxygen metabolites (ROMs), very little information is available regarding the ...
F S Laroux +4 more
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Superoxide, superoxide dismutase and ischemic injury.
Current opinion in investigational drugs (London, England : 2000), 2002Oxidative stress results from an oxidant/antioxidant imbalance: an excess of oxidants relative to the antioxidant capacity. Recent evidence strongly suggests that oxidant stress plays a major role in several aspects of ischemia and reperfusion. Immunohistochemical and biochemical evidence demonstrate the significant role of reactive oxygen species, in ...
Salvemini, Daniela, CUZZOCREA, Salvatore
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Superoxide-Superoxide Oxidoreductase Activity of the Captopril-Copper Complex
Archives of Medical Research, 2002The purpose of this study was to determine whether the interaction of captopril, an angiotensin-converting enzyme inhibitor, with copper could modify the superoxide dismutase activity of this metal. Results may help to explain the interaction of captopril with reactive oxygen species in the stunned myocardium where substantial mobilization of copper ...
Eduardo Muñoz +4 more
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Keratinocyte Superoxide Generation
Free Radical Biology and Medicine, 1998We have demonstrated using the reduction of cytochrome c, that the keratinocyte cell line H357 generates superoxide at significant rates (8.36 nmol/h/10[6] cells). The rate of superoxide release decreased as the cells reached confluence. Superoxide production was increased more than twofold following preincubation with IL-1beta, or by the addition of ...
Turner, CP, Toye, AM, Jones, OTG
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