Results 71 to 80 of about 177 (92)

The SOD1 Inhibitor, LCS-1, Oxidizes H2S to Reactive Sulfur Species, Directly and Indirectly, through Conversion of SOD1 to an Oxidase. [PDF]

open access: yesAntioxidants (Basel)
Olson KR   +11 more
europepmc   +1 more source

Aggregability of the SQSTM1/p62-based aggresome-like induced structures determines the sensitivity to parthanatos. [PDF]

open access: yesCell Death Discov
Hamano S   +13 more
europepmc   +1 more source

Supersulfide catabolism participates in maladaptive remodeling of cardiac cells

open access: yesJournal of Pharmacological Sciences
The atrophic myocardium resulting from mechanical unloading and nutritional deprivation is considered crucial as maladaptive remodeling directly associated with heart failure, as well as interstitial fibrosis. Conversely, myocardial hypertrophy resulting from hemodynamic loading is perceived as compensatory stress adaptation. We previously reported the
Motohiro Nishida   +2 more
exaly   +3 more sources
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Supersulfide-Mediated Signaling during Differentiation and De-Differentiation

2021
Tsuyoshi Takata   +4 more
exaly   +2 more sources

Regulation of innate immune and inflammatory responses by supersulfides

International Immunology
AbstractInnate immunity plays an important role in host defense against microbial infections. It also participates in activation of acquired immunity through cytokine production and antigen presentation. Pattern recognition receptors such as Toll-like receptors and nucleotide oligomerization domain-like receptors sense invading pathogens and associated
Hiroyasu Tsutsuki   +3 more
openaire   +2 more sources

Dynamic transformation of the sulfur metabolome during natto fermentation: Supersulfide omics study

Nitric Oxide - Biology and Chemistry
Supersulfides are sulfur species with catenated sulfur atoms, such as cysteine hydropersulfide (CysSSH). Although supersulfides are biologically important metabolites owing to their unique chemical properties, their transformation in plants via microbial fermentation remains unknown. Natto is a traditional Japanese food prepared from soybeans fermented
Tomoaki Ida   +2 more
exaly   +4 more sources

Redox Regulation of Xenobiotics by Reactive Sulfur and Supersulfide Species

Antioxidants and Redox Signaling
Significance: Routine exposure to xenobiotics is unavoidable during our lifetimes. Certain xenobiotics are hazardous to human health, and are metabolized in the body to render them less toxic. During this process, several detoxification enzymes cooperatively metabolize xenobiotics.
Tianli Zhang   +2 more
exaly   +3 more sources

Development and application of a highly specific whole-cell biosensor for supersulfide detection in environmental samples

Biosensors and Bioelectronics
Supersulfides are a class of sulfur compounds in either zero-valent or monovalent negative states, such as elemental sulfur, inorganic polysulfides, and organic polysulfides, and they play crucial roles in biological systems, environmental sulfur cycling, and Li-S batteries. However, accurate quantification of these compounds remains challenging due to
Huaiwei Liu, Xianzhe Gong, Ning Du
exaly   +3 more sources

Quantitative profiling of supersulfides naturally occurring in dietary meats and beans

Analytical Biochemistry
Sulfur is essential in the inception of life and crucial for maintaining human health. This mineral is primarily supplied through the intake of proteins and is used for synthesizing various sulfur-containing biomolecules. Recent research has highlighted the biological significance of endogenous supersulfides, which include reactive persulfide species ...
Shingo Kasamatsu   +10 more
openaire   +2 more sources

Supersulfides support bone growth by promoting chondrocyte proliferation in the growth plates

Journal of Oral Biosciences
While chondrocytes have mitochondria, they receive little O2 from the bloodstream. Sulfur respiration, an essential energy production system in mitochondria, uses supersulfides instead of O2. Supersulfides are inorganic and organic sulfides with catenated sulfur atoms and are primarily produced by cysteinyl tRNA synthetase-2 (CARS2).
Yuji, Sasama   +8 more
openaire   +2 more sources

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