Results 91 to 100 of about 2,061,454 (343)

A Self-Supervised Approach to Reconstruction in Sparse X-Ray Computed Tomography [PDF]

open access: green, 2022
Rey Mendoza   +6 more
openalex   +1 more source

Supervisor Self-disclosure: Supervisees\u27 Experiences and Perspectives [PDF]

open access: yes, 2011
Twelve graduate-level supervisees were interviewed regarding their experiences of supervisor self-disclosure (SRSD); data were analyzed using consensual qualitative research.
Edwards, Lisa   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Internship Organization for Bachelor Students of Psycho-pedagogical Education (Primary School Teacher) as Training Direction

open access: yesПсихологическая наука и образование (2007. Online), 2015
The article presents the experience of testing the internship program for basic professional educational bachelor program of "Psycho-pedagogical Education" (Primary School Teacher) training direction in a network of university and school.
Zakharova I.M.
doaj   +1 more source

Monetary policy, the provision of financial stability and banking supervision [PDF]

open access: yes, 2012
This note discusses why it might be desirable for a central bank to have a microprudential supervisory role and why a single micro-prudential supervisor might be better than a collection of national supervisors. It argues that central banks should not be
Sibert, Anne
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

The Economic Pay-Offs To On-The-Job Training In Routine Service Work [PDF]

open access: yes, 2005
This study examines the relationship between on-the-job training and job performance among 3,408 telephone operators in a large unionized telecommunications company.
Batt, Rosemary, Liu, Xiangmin
core   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

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