Results 81 to 90 of about 505,633 (274)

Supervisory Multi Switching Data Driven Control Theory and Application

open access: yesIEEE Access
Due to the varying circumstances, thus resulting in frequently changed system plant, the controller must also varies with time increases. This paper proposes supervisory multi switching data driven control strategy from both theoretical analysis and ...
Hong Wangjian, Cao Lei
doaj   +1 more source

Tax wedge in Croatia, Italy, Ireland, the Netherlands and Spain

open access: yesFinancial Theory and Practice, 2016
Each country has a unique tax system, comprising a number of components reflecting the taxation and economic policy of a country. The aim of this paper is to analyse and compare the tax burden on labour income in Croatia, Italy, Spain, Ireland and the ...
Maja Cundić
doaj   +1 more source

RESTRUKTURIRANJE DRUŠTAVA U POTEŠKOĆAMA I TRŽIŠTE KAPITALA – VRSTE I UPRAVLJANJE SUKOBOM INTERESA

open access: yesZbornik Pravnog Fakulteta Sveučilišta u Rijeci, 2018
Predmet rada je istražiti na koji način tržište kapitala može biti platforma za restrukturiranje društava u poteškoćama te koji su financijski posrednici tipično uključeni u te postupke. Nakon toga analizirat će se sukobi interesa koji se mogu pojaviti u
Morana Derenčinović Ruk
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Nursing Managers’ Coronary Care Unit Management Experience

open access: yesIranian Journal of Nursing and Midwifery Research
Background: The Coronary Care Unit (CCU) requires effective managers to consider- the patient’s acute condition. Studies have indicated that nursing managers of such units face many challenges. The purpose of the study is to explain nursing managers’ CCU
Azam Zare   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Composition of Supervisory Boards in Germany: Inside or Outside Control of Banks? [PDF]

open access: yes
This paper examines the composition of supervisory boards of German banks for a sample of 41 large banks in the period 1999-2006. We find that the supervisory board structure reflects both outside control by shareholders and inside control by ...
Doris Neuberger   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Mediação e acompanhamento na formação, educação e desenvolvimento profissional Mediación y acompañamiento en la formación educación e desarrollo profesional Mediating and monitoring training, education and professional development

open access: yesRevista de Enfermagem Referência, 2012
As políticas de educação e ensino superior reconhecem a importância da aprendizagem mediada, no complexo processo de desenvolvimento da cadeia educativa: da gestão da informação à construção de conhecimento e sabedoria para agir.
Manuel Alves Rodrigues   +1 more
doaj  

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