Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
IEEE AccessA power distribution system is usually composed of a number of distribution substations and distribution lines, where the latter are fragile and often suffer from faults, leading to serious local power shortages.
Zhongyuan Jiang, Huan Wang, Wenjie Wang
doaj +1 more source
A deterministic approach for design of supervisory control of LPV systems with delay. [PDF]
PLoS One, 2021 Zahid CN, Salim M, Riaz RA, Iqbal J.
europepmc +1 more source
Economic supervisory predictive control of a hybrid power generation plant [PDF]
, 2015 This work deals with the development of an economic supervisory predictive control method for the management of a hybrid renewable energy system. The hybrid cell integrates solar panels, a gas microturbine and a storage unit.
COLAS, Frédéric +3 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Hysteresis-based supervisory control with application to non-pharmaceutical containment of COVID-19. [PDF]
Annu Rev Control, 2021 Bin M +6 more
europepmc +1 more source
Supervisory control based on closed-loop adaptive control approach of nonlinear systems: application to CSTR process [PDF]
, 2011 International audienceIn the last few years there has been a great deal of interest in the application of adaptive and supervisory control of linear systems using multi-models and multi-controllers based on switching and tuning algorithms.
Lehouche, Hocine +5 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Sensors Data Analysis in Supervisory Control and Data Acquisition (SCADA) Systems to Foresee Failures with an Undetermined Origin. [PDF]
Sensors (Basel), 2021 Maseda FJ +5 more
europepmc +1 more source
Supervisory Stability Assurance Layer for Hierarchical Plant-wide Process Control [PDF]
, 2010 An independent stability assurance layer for the multivariable controller in the hierarchical control architecture is introduced in this paper. This stability layer provides an integrated safety and protection measure to process control systems from ...
Tri Tran, Tran, T, Jie Bao, Bao, J
core +1 more source