Results 81 to 90 of about 387,639 (348)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Improving the reliability of the power system in postfault condition [PDF]

E3S Web of Conferences
Priority tasks in electric power transmission are: the reliability of power supply to consumers and the efficiency of energy resources use. In postfault steady-state heavy modes of power system operation, these tasks are mainly solved by supervisory ...
Solovyev Ivan, Motovilov Alexey, Hvijuzov Mikhail, Emelyanov Alexander   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Attack-Resilient Supervisory Control under Energy-Bounded Attacks

, 2023
Jingshi Yao, Shaoyuan Li, Xunyuan Yin, Xiang Yin   +3 more
openalex   +1 more source

Supervisory Control Strategy Development [PDF]

, 2007
Task 4 of this collaborative effort between ORNL, Brazil, and Westinghouse for the International Nuclear Energy Research Initiative entitled “Development of Advanced Instrumentation and Control for an Integrated Primary System Reactor” focused on the design of the hierarchical supervisory control for multiple-module units.
Storrick, Gary D., Petrovic, Bojan
openaire   +2 more sources

Displays for supervisory control of manipulators [PDF]

The problem of displaying information generated by sensors attached to the terminal device of a remotely controlled manipulator is considered. The sensors under consideration are proximity, force-torque, tactile and slip-page sensors. The paper describes
Bejczy, A. K., Paine, G.
core   +1 more source

Pengaruh Penerapan Peran Komite Audit, Peran Dewan Pengawas Syariah, dan Efektivitas Pengendalian Intern Atas Pelaporan Keuangan terhadap Kualitas Pelaporan Keuangan (Studi Empiris pada Bank Syariah di Indonesia) [PDF]

, 2014
This study examines the effect of audit committee role, shari’a supervisory board role, and internal control over financial reporting effectiveness, on financial reporting quality. The data is taken by questionnaire from 173 employees (group head ...
Rini, R. (Rini)
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Collision Avoidance for Parametric Railway Lines by Supervisor Control

IEEE Access
In the present paper, two collision avoidance supervisor schemes are developed for a single line and one-way railway system, with a parametric number of stations and a parametric number of trains.
Fotis N. Koumboulis, Dimitrios G. Fragkoulis, George E. Panagiotakis, Konstantinos A. Ioannou, Alexandros Nikolopoulos   +4 more
doaj   +1 more source

Supervisory control for conventional unitary air conditioning system [PDF]

, 2012
The Supervisory control for conventional unitary air conditioning system is conceptually designed based on Programmable Logic Control (PLC) system.
Morrison Buah, Lorothy
core