Results 111 to 120 of about 1,245,802 (290)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Replacement of soybean meal by cottonseed meal 38% in multiple supplements for grazing beef heifers Substituição do farelo de soja por farelo de algodão 38% em suplementos múltiplos para novilhas de corte em pastejo

Revista Brasileira de Zootecnia, 2011
The objective of this work was to evaluate the effect of using multiple supplements with different levels of cottonseed meal 38% on intake, total apparent digestibility of dietary components, efficiency of microbial synthesis and productive performance ...
L.V. Barros, M.F. Paulino, S.C. Valadares Filho, E. Detmann, F.G. Silva, E.E.L. Valente, S.A. Lopes, L.S. Martins   +7 more
doaj   +1 more source

Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice [PDF]

, 2014
Kristyn A Liu1†, Laura M Lashinger1†, Audrey J Rasmussen1† and Stephen D Hursting12* Author Affiliations 1 Department of Nutritional Sciences, University of Texas at Austin, Austin, TX 78723, USA 2 Department of Molecular Carcinogenesis, University ...
Hursting, Stephend D., Lashinger, Laura M., Liu, Kristyn A., Rasmussen, Audrey J.   +3 more
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Rumen dynamics of neutral detergent fiber in cattle fed low-quality tropical forage and supplemented with nitrogenous compounds Dinâmica ruminal da fibra em detergente neutro em bovinos alimentados com forragem tropical de baixa qualidade e suplemento com compostos nitrogenados

Revista Brasileira de Zootecnia, 2009
The aim of this work was to evaluate the effects of supplementation with nitrogenous compounds on rumen dynamics of neutral detergent fiber (NDF) in cattle fed low-quality tropical forage.
Cláudia Batista Sampaio, Edenio Detmann, Isis Lazzarini, Marjorrie Augusto de Souza, Mário Fonseca Paulino, Sebastião de Campos Valadares Filho   +5 more
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Creatine and glycerol hyperhydration in trained subjects prior to exercise in the heat. [PDF]

, 2007
The authors examined the effects of combined creatine (Cr) and glycerol (Gly) supplementation on responses to exercise in the heat. Subjects (N = 24) were matched for body mass and assigned to either a Cr or placebo (Pl) group. Twice daily during two 7-d
Easton, Chris, Pitsiladis, Yannis P, Turner, Stephen   +2 more
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Effect of daily versus weekly home fortification with multiple micronutrient powder on haemoglobin concentration of young children in a rural area, Lao People's Democratic Republic: a randomised trial

Nutrition Journal, 2011
Background Multiple micronutrient deficiencies, in particular iron deficiency anaemia (IDA) is a severe public health problem in Lao People's Democratic Republic (Lao PDR).
Kounnavong Sengchanh, Sunahara Toshihiko, Mascie-Taylor C G Nicholas, Hashizume Masahiro, Okumura Junko, Moji Kazuhiko, Boupha Boungnong, Yamamoto Taro   +7 more
doaj   +1 more source

Total parenteral nutrition and carnitine supplementation practices in preterm neonates - results of a national survey [PDF]

, 2013
Thesis (M.A.)--Boston UniversityBackground: The goal of postnatal total parenteral nutrition (TPN) in premature neonates (PT) is to mimic the intrauterine environment of the fetus. Micronutrients are essential for optimal development.
Khalid, Sabeen
core   +1 more source