Results 111 to 120 of about 1,933,492 (363)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

EFEITO DO CREEP FEEDING E CREEP GRAZING NAS CARACTERÍSTICAS DA PASTAGEM DE TIFTON E AZEVÉM E NO DESEMPENHO DE OVINOS

Ciência Animal Brasileira, 2012
The objective of this study was to evaluate the influence of creep feeding and creep grazing on the pasture characteristics and on performance and productivity of sheep. Three systems of lambs production on Tifton 85 (Cynodon spp.) pastures oversown with
Cláudio José Araújo da Silva1, 2, 3, 4, 3,, Alda Lúcia Gomes Monteiro, Sergio Rodrigo Fernandes, César Henrique Espírito Candal Poli, Odilei Rogério Prado, Damaris Ferreira de Souza   +5 more
doaj  

Coenzyme Q10 Supplementation in Aging and Disease

Frontiers in Physiology, 2018
Coenzyme Q (CoQ) is an essential component of the mitochondrial electron transport chain and an antioxidant in plasma membranes and lipoproteins. It is endogenously produced in all cells by a highly regulated pathway that involves a mitochondrial ...
J. D. Hernández-Camacho, M. Bernier, G. López-Lluch, P. Navas   +3 more
semanticscholar   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Vitamin D supplementation and breast cancer prevention : a systematic review and meta-analysis of randomized clinical trials [PDF]

, 2013
In recent years, the scientific evidence linking vitamin D status or supplementation to breast cancer has grown notably. To investigate the role of vitamin D supplementation on breast cancer incidence, we conducted a systematic review and meta-analysis ...
Nancy Santesso (435397), Pizzuti, Laura, Pizzuti, L, Montella, Maurizio, Nancy Santesso, Santesso Nancy, Patrizia Vici (85361), Santesso, Nancy, Barba, Maddalena, Anna Crispo (435403), Mariani, Luciano, Barba M., Maugeri-Saccà, Marcello, Maddalena Barba, Montella Maurizio, Laura Pizzuti, Mottolese Marcella, Sergi D., Patrizia Vici, Domenico Sergi, Francesca Sperati, Stranges, Saverio, Luigi Di Lauro (435401), Vici Patrizia, Luciano Mariani (435398), Antonio Giordano, Barba Maddalena, Montella, M, Marcella Mottolese (85368), Sperati, Francesca, Francesca Sperati (95245), Mottolese M., Sperati Francesca, Saverio Stranges, Mariani L., Crispo, A, Di Lauro, L, Laura Pizzuti (435400), Pizzuti L., Saverio Stranges (73786), Marcella Mottolese, Giordano, A, Pizzuti Laura, Crispo A., Marcello Maugeri-Saccà, Barba, M, Maugeri-Saccà Marcello, Stranges, S, Santesso N., Di Lauro, Luigi, Stranges S., Maurizio Montella, Marcello Maugeri-Saccà (435396), Antonio Giordano (55096), Vici P., Sperati, F, Di Lauro Luigi, Sergi, D, Sergi, Domenico, Santesso, N, Mariani, L, Luigi Di Lauro, Giordano, Antonio, MD, Giordano A., Mottolese, M, Giordano, Antonio|, Stranges Saverio, Di Lauro L., Mottolese, Marcella, Maddalena Barba (82927), Sergi Domenico, Crispo Anna, Luciano Mariani, Maurizio Montella (435402), Sperati F., Giordano Antonio, Vici, P, Montella M., Crispo, Anna, Maugeri-Saccà, M, Vici, Patrizia, Mariani Luciano, Anna Crispo, Domenico Sergi (435399), Maugeri-Sacca M.   +84 more
core   +1 more source

Uso de Phaseolus vulgaris y Vigna sinensis como extensores de una bebida láctea fermentada

Archivos Latinoamericanos de Nutrición, 2004
El objetivo de este trabajo fue desarrollar un nuevo tipo de bebida láctea, extendida con variedades claras de Phaseolus vulgaris (caraota) y Vigna sinensis (frijol). Para la formulación de las bebidas lácteas se prepararon extractos estériles de caraota
Marisela Granito, Lesma Trujillo, Marisa Guerra   +2 more
doaj  

Vitamin D Supplementation Guidelines for General Population and Groups at Risk of Vitamin D Deficiency in Poland—Recommendations of the Polish Society of Pediatric Endocrinology and Diabetes and the Expert Panel With Participation of National Specialist Consultants and Representatives of Scientific Societies—2018 Update

Frontiers in Endocrinology, 2018
IntroductionVitamin D deficiency is an important public health problem worldwide. Vitamin D deficiency confers a significant risk for both skeletal and non-skeletal disorders and a number of lifelong negative health outcomes.
Agnieszka Rusińska, Paweł Płudowski, Mieczysław Walczak, Maria K. Borszewska-Kornacka, Artur Bossowski, Danuta Chlebna-Sokół, Justyna Czech-Kowalska, Anna Dobrzańska, Edward Franek, Ewa Helwich, Teresa Jackowska, Maria A. Kalina, Jerzy Konstantynowicz, Janusz Książyk, Andrzej Lewiński, Jacek Łukaszkiewicz, Ewa Marcinowska-Suchowierska, Artur Mazur, Izabela Michałus, Jarosław Peregud-Pogorzelski, Hanna Romanowska, Marek Ruchała, Piotr Socha, Mieczysław Szalecki, Mieczysław Szalecki, Mirosław Wielgoś, Danuta Zwolińska, Arkadiusz Zygmunt   +27 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Zinc Supplementation during Pregnancy: A Randomized Controlled Trial [PDF]

Zinc deficiency during pregnancy has been related to adverse pregnancy outcomes. However, the results of zinc-supplementation trials have not been consistent in improvement of pregnancies outcomes.
مهاجری, منوچهر, امینی ثانی, نیره, شمشیرگران, سید مرتضی, اهدایی وند, فرناز, پورفرضی, فرهاد, صادقیه اهری, سعید   +5 more
core  

Overestimation of Vitamin a Supplementation Coverage from District Tally Sheets Demonstrates Importance of Population-Based Surveys for Program Improvement: Lessons from Tanzania. [PDF]

, 2013
Tanzania has conducted a national twice-yearly Vitamin A supplementation (VAS) campaign since 2001. Administrative coverage rates based on tally sheets consistently report >90% coverage; however the accuracy of these rates are uncertain due to potential ...
Rolf Klemm, Rambeloson, Zo, Rambeloson Zo, Subramaniam, Hamsa, Hamsa Subramaniam, Subramaniam Hamsa, Nyhus Dhillon, Christina, Klemm, Rolf, Mulokozi, Generose, Mulokozi Generose, Generose Mulokozi, Klemm Rolf, Zo Rambeloson, Nyhus Dhillon Christina, Christina Nyhus Dhillon   +14 more
core   +1 more source