Results 101 to 110 of about 224,777 (352)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Persistence of, and interrelation between, horizontal and vertical technology alliances. [PDF]

open access: yes
The authors explore to what extent there is persistence in, and interrelation between, alliance strategies with different partner types (customers, suppliers, competitors).
Belderbos, Rene   +2 more
core   +3 more sources

The Nexus of Green Supplier Integration for Green Innovation in Manufacturing Firms [PDF]

open access: gold, 2023
Jie Cheng   +3 more
openalex   +1 more source

Supply chain integration in New Zealand public hospitals: impact on supplier commercial relationships and order fulfilment [PDF]

open access: yes, 2011
Although there is general understanding on the importance of supply chain integration (SCI), little is known regarding SCI operational issues and their impact on supplier commercial relationships and order fulfilment in public hospitals.
Msimangira, Kabossa Adolf Barthazar
core  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

An Integrated of Neutrosophic-ANP Technique for Supplier Selection

open access: yesNeutrosophic Sets and Systems, 2019
This study provides a novel integrated multi-criteria decision-making approach to supplier selection problems in neu-trosophic environment. The main objective is to study the Analytic network process (ANP) technique in environment of neutro-sophic and present a new method for formulation problem of Multi-Criteria Decision-Making (MCDM) in network ...
Abdel Nasser H. Zaied   +2 more
openaire   +3 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

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