Results 131 to 140 of about 611,924 (357)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

The effect of supply chain integration, management commitment, and sustainable supply chain practices on non-profit organizations performance using SEM-FsQCA: Evidence from Afghanistan

open access: yesSustainable Futures
This study explores the impact of supply chain integration, management commitment, and sustainable supply chain practices on the performance of non-profit organizations in Afghanistan.
Sayed Khalid Shahzad   +4 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

The Joint Impact of Supply Chain Integration and Quality Management on the Performance of Pork Processing Firms in China [PDF]

open access: yes
It is widely acknowledged that competition is no longer between individual firms, but between supply chains. A number of studies have indicated that supply chain integration and quality management have become essential to obtain competitive advantage ...
Han, Jiqin   +2 more
core   +1 more source

The Effect of Information Security Management on Organizational Processes Integration in Supply Chain

open access: yesIranian Journal of Information Processing & Management, 2012
: The major purpose of this article was that how information security management has effect on supply chain integration and the effect of implementing "information security management system" on enhancing supplies chain integration.
Mohsen Shafiei Nikabadi   +2 more
doaj  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

COMPETITIVE ADVANTAGE BY INTEGRATED E-BUSINESS IN SUPPLY CHAINS: A STRATEGIC APPROACH [PDF]

open access: yes
This paper reports findings of the competitive advantage of supply chain integration and the crucial role of integrated e-business to deliver those benefits.
Daniel SERBANICA, Gheorghe MILITARU
core  

WSN based intelligent cold chain management [PDF]

open access: yes, 2008
This paper presents a cold chain monitoring system which is implemented by using ubiquitous computing technologies, Radio Frequency Identification (RFID) & Wireless Sensor Network (WSN).
Aung, MM   +4 more
core  

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