Results 61 to 70 of about 723,577 (358)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Industry 4.0-Enabled Supply Chain Performance: Do Supply Chain Capabilities and Innovation Matter?

Logistics
Background: The present study investigates Industry 4.0’s (I4.0) impact on supply chain capabilities (SCCs), supply chain innovation (SCI), and supply chain performance (SCP). The influence of SCCs and SCI on SCP is also explored.
Ayman Bahjat Abdallah, Hamza Ahmad Almomani, Zu’bi M. F. Al-Zu’bi   +2 more
doaj   +1 more source

Impact of Green Supply Chain on Supply Chain Performance

WSEAS TRANSACTIONS ON BUSINESS AND ECONOMICS, 2022
The purpose of this paper is empirically assessment of the impact of the green supply chain on supply chain performance in terms of social, operational, and environmental, for Jordanian chemical industries. In this paper, the proposed model was developed based on literature review and previous exploratory studies related to GSC and different kinds of ...
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The links between supply chain risk management practices, supply chain integration and supply chain performance in Southern Vietnam: A moderation effect of supply chain social sustainability

Cogent Business & Management, 2021
This research examines the impact of supply chain risk management on supply chain integration, supply chain performance, and the moderation effects of supply chain social sustainability on these relationships.
Ngoc Hong Duong, Quang-An Ha
doaj   +1 more source

Modeling Supply Chain Performance

Procedia Manufacturing, 2017
Abstract European countries actually adopt industry 4.0 and supply chain 4.0 philosophy. Enterprise modelling methodologies define enterprise as a system, which can integrate new technologies, Internet of things, automation and robotics in collaboration with people.
Paul Eric Dossou, Meriem Nachidi
openaire   +1 more source

Modelling the impact of climate change risk on supply chain performance

International Journal of Production Research, 2020
Climate change is among the top global risks due to its growing adverse impact on businesses. However, few empirical studies address this imminent risk from a supply chain perspective.
M. Kara, Abhijeet Ghadge, U. Bititci
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Relationship Stability and Supply Chain Performance for SMEs: From Internal, Supplier, and Customer Integration Perspectives

Mathematics, 2020
This study examined the relationship between supply integration and relationship stability and the relationship between relationship stability and performance; furthermore, the moderation effect of environmental uncertainty on supply chain integration ...
Tsu-Ming Yeh, Fan-Yun Pai, Liang-Chuan Wu   +2 more
doaj   +1 more source