Results 51 to 60 of about 2,656,520 (276)
Single-lipid dynamics in phase-separated supported lipid bilayers [PDF]
ABSTRACT Phase separation is a fundamental organizing mechanism on cellular membranes. Lipid phases have complex dependencies on the membrane composition, curvature, tension, and temperature. Single-molecule diffusion measures a key characteristic of membrane behavior and relates to the effective membrane viscosity ...
Xinxin Woodward, Christopher V. Kelly
openaire +3 more sources
Hydrogen Bond Networks Near Supported Lipid Bilayers from Vibrational Sum Frequency Generation Experiments and Atomistic Simulations [PDF]
We report vibrational sum frequency generation (SFG) spectra in which the C–H stretches of lipid alkyl tails in fully hydrogenated single- and dual-component supported lipid bilayers are detected along with the O–H stretching continuum above ...
Paul E., Ohno +8 more
core +1 more source
Determining the Bending Rigidity of Free-Standing Planar Phospholipid Bilayers
We describe a method to determine membrane bending rigidity from capacitance measurements on large area, free-standing, planar, biomembranes. The bending rigidity of lipid membranes is an important biological mechanical property that is commonly ...
Oscar Zabala-Ferrera +2 more
doaj +1 more source
Porous Materials to Support Bilayer Lipid Membranes for Ion Channel Biosensors
To identify materials suitable as membrane supports for ion channel biosensors, six filter materials of varying hydrophobicity, tortuosity, and thickness were examined for their ability to support bilayer lipid membranes as determined by electrical ...
Thai Phung +3 more
doaj +1 more source
Fabrication of Supported Lipid Bilayer on Graphene Oxide
Planar lipid bilayers of dioleoylphosphatidylcholine was prepared on graphene oxide (GO), as a fundamental platform for biosensing in plasma membrane model using graphene. The GO flakes were prepared according to modified Hummer's method, and deposited on thermally oxidized SiO2/Si surfaces.
Okamoto, Yoshiaki +5 more
openaire +1 more source
Electrophoretic Measurements of Lipid Charges in Supported Bilayers [PDF]
While electrophoresis in lipid bilayers has been performed since the 1970s, the technique has until now been unable to accurately measure the charge on lipids and proteins within the membrane based on drift velocity measurements. Part of the problem is caused by the use of the Einstein-Smoluchowski equation to estimate the electrophoretic mobility of ...
Matthew F, Poyton, Paul S, Cremer
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Investigating Lipid-Protein Interactions Using Supported Lipid Bilayers
Membrane proteins play vital roles in cell function and as such represent the targets of over 60% of pharmaceuticals on the market1. Lipid interactions with membrane proteins are a crucial but often overlooked effector of cell physiology.
Richards, Mark
core +6 more sources
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Perturbation of Hydrogen Bonding Networks over Supported Lipid Bilayers by Poly (Allylamine Hydrochloride) [PDF]
Water is vital to many biochemical processes and is necessary for driving many fundamental interactions of cell membranes with their external environments, yet it is difficult to probe the membrane/water interface directly and without the use of external
Paul E., Ohno +5 more
core +1 more source

