Results 71 to 80 of about 35,591 (294)

Formulation and in vitro Evaluation of In-situ Gelling Liquid Suppositories for Naproxen

open access: yesIraqi Journal of Pharmaceutical Sciences, 2017
In-situ gelation is a process of gel formation at the site of application, in which a drug product formulation that exists as a liquid has been transformed into a gel upon contact with body fluids.
Noor N. Al-Wiswasi   +1 more
semanticscholar   +1 more source

Association of Proton Pump Inhibitor and Potassium‐Competitive Acid Blocker Use With Discontinuation and Intolerance of Oral 5‐Aminosalicylic Acid in Patients With Ulcerative Colitis

open access: yesJGH Open, Volume 10, Issue 2, February 2026.
ABSTRACT Aims Proton pump inhibitors (PPIs) and potassium‐competitive acid blockers (PCABs) are widely used for acid‐related disorders. Recent studies have raised concerns that acid suppression may alter gut microbiota and drug pharmacokinetics, potentially influencing therapeutic outcomes in patients with inflammatory bowel disease.
Shinsuke Otagiri   +4 more
wiley   +1 more source

SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION

open access: yesРазработка и регистрация лекарственных средств, 2019
In this material were reviewed biopharmaceutical aspects of suppositories – described the relation between rectal route of administration, bioaccessibility and principles of dosage forms formulation.
N. B. Diomina, M. N. Anurova
doaj  

Activity and Stability Studies of Verbascoside, a Novel Antioxidant, in Dermo-Cosmetic and Pharmaceutical Topical Formulations

open access: yesMolecules, 2011
We here report the results of our investigations carried out on verbascoside, a phenylpropanoid glycoside known for its antioxidant, anti-inflammatory and photoprotective actions.
Anna Baldisserotto   +7 more
doaj   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, Volume 16, Issue 1, Page 116-126, January 2026.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

RESEARCH ON MICROBIOLOGICAL PURITY OF “PHYTOPROST” AND “TAMSULOPROST” SUPPOSITORIES [PDF]

open access: yesAnnals of Mechnikov's Institute, 2014
Results of the tests on microbiological purity of the test samples of "Tamsuloprost" and "Phytoprost" suppositories for the treatment of prostate diseases have shown that no viable cells of fungi were found in the preparations, the number of viable ...
Gritsenko V. I.   +2 more
doaj  

STUDY OF STRUCTURAL-MECHANICAL PROPERTIES OF VINPOCETINE SUPPOSITORIES

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014
Using alternative absorption path for vinpocetine, in particular rectal, will allow to improve its bioavailability, efficiency in comparison with traditional oral dosage forms and will provide practical cardiology with accessible domestic pharmaco ...
N. А. Nagornaya   +2 more
doaj   +1 more source

Identifying and managing constipation in older people [PDF]

open access: yes, 2016
Constipation is a major problem in residential care. It is a condition which, if left untreated, can result in major distress and health problems for sufferers.
Lee, Amanda
core   +1 more source

Immune‐Mediated Thrombocytopenia in an Ulcerative Colitis Patient After Initiating Filgotinib Treatment: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Timeline of events ABSTRACT Moderate‐to‐severe ulcerative colitis can be effectively treated with JAK‐1 inhibition, but platelet counts should be closely monitored, especially in active disease. We confirmed immune‐mediated thrombocytopenia (ITP) in one of our patients after the initiation of filgotinib. Whether this was drug‐induced is uncertain.
M. J. van der Hoff   +2 more
wiley   +1 more source

Research on microbiological purity of “Phytoprost” and “Tamsuloprost” suppositories

open access: yesAnnals of Mechnikov's Institute, 2020
Results of the tests on microbiological purity of the test samples of "Tamsuloprost" and "Phytoprost" suppositories for the treatment of prostate diseases have shown that no viable cells of fungi were found in the preparations, the number of viable cells
V Gritsenko, O Ruban, T Osolodchenko
doaj  

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