Results 231 to 240 of about 424,245 (266)

Genetic suppression of malignancy.

IARC scientific publications, 1989
Genetic tumours of Xiphophorus are one of the classical experimental models that underline the concept that cancers develop as a result of abnormal gene expression. Formal genetics has indicated that cancer development in Xiphophorus starts when oncogenes are expressed abnormally due to elimination of tumour suppressor genes.
openaire   +1 more source

A genetic basis for tumour suppression.

Ciba Foundation symposium, 1989
The technique of somatic cell hybridization has established the phenomenon of tumour suppression and provided evidence for a genetic basis for suppression. Further refinements aimed at eventually identifying 'tumour suppressor' genes include the use of monochromosome transfer via microcell hybridization.
openaire   +1 more source

Genetic testing in prostate cancer management: Considerations informing primary care

Ca-A Cancer Journal for Clinicians, 2022
Mary-Ellen Taplin, Veda Giri, Jacob Berchuck   +2 more
exaly  

Cancer genetics and cancer suppression.

Cancer detection and prevention, 1990
Identification of normal growth and differentiation-inducing proteins and how they interact in normal development has made it possible to identify the molecular basis of normal development and the mechanisms that uncouple growth and differentiation so as to produce malignant cells.
openaire   +1 more source

Genetic principles of tumor suppression

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1989
openaire   +2 more sources

A saturated map of common genetic variants associated with human height

Nature, 2022
Shefali Verma, Jer-Yuarn Wu, Nancy Heard-Costa   +2 more
exaly  

Suppression of genetic melanoma in the fish Xiphophorus.

Ciba Foundation symposium, 1989
Hybrids between certain species of the teleost Xiphophorus predictably develop melanomas. Classical Mendelian crossing experiments have allowed us to identify genetic loci involved in eliciting and in suppressing tumorigenesis. The overall picture is that melanoma formation results from functional elimination of a suppressor locus allowing abnormal ...
openaire   +1 more source

Family Physicians and Referrals of Low-risk Women for BRCA1/2 Genetic Services

Ca-A Cancer Journal for Clinicians, 2009
M D Pinkowish
exaly  

Missed therapeutic and prevention opportunities in women with BRCA‐mutated epithelial ovarian cancer and their families due to low referral rates for genetic counseling and BRCA testing: A review of the literature

Ca-A Cancer Journal for Clinicians, 2017
Walter Gotlieb, Paul Hoskins
exaly  

A global reference for human genetic variation

Nature, 2015
D Kalra, Jakob Berg Jespersen, Stephen Schaffner   +2 more
exaly