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Loss of CsrA in <i>Acinetobacter baumannii</i> leads to lethal dysregulation of alanine metabolism. [PDF]
Proc Natl Acad Sci U S ASava RL, Gebhardt MJ.
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miRNAs bridging the gap between the tumor microenvironment and liquid biopsy in cutaneous melanoma. [PDF]
Front ImmunolNeagu M, Dobre EG, Constantin C.
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1974
Suppressors are genes which suppress the expression of mutant phenotypes. The suppressors can be considered to be mutant genes themselves since they are generally not found in the wild type strains but are obtained by selecting for revertants of the mutant phenotype.
D C, Hawthorne, U, Leupold
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Suppressors are genes which suppress the expression of mutant phenotypes. The suppressors can be considered to be mutant genes themselves since they are generally not found in the wild type strains but are obtained by selecting for revertants of the mutant phenotype.
D C, Hawthorne, U, Leupold
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Suppressor T Cells and Suppressor Factor
Hospital Practice, 1978The ability to suppress antibody response to specific antigens has been found to be inherent in a subpopulation of T lymphocytes. The suppressor pathway has been shown to involve an initial T-cell clone that that elaborates a soluble factor which, in turn, induces a second cohort of effector cells.
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Blood, 2009
In this issue of Blood , Brockman and colleagues demonstrate that active HIV replication rapidly triggers production of the immunosuppressive cytokine IL-10 and that IL-10 reversibly inhibits HIV-directed T-cell activity.[1][1] Application of these findings may ultimately lead to therapies ...
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In this issue of Blood , Brockman and colleagues demonstrate that active HIV replication rapidly triggers production of the immunosuppressive cytokine IL-10 and that IL-10 reversibly inhibits HIV-directed T-cell activity.[1][1] Application of these findings may ultimately lead to therapies ...
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Neuron, 1991
For the past decade, cellular oncogenes have attracted the attention of biologists intent on understanding the molecular origins of cancer. As the present decade unfolds, oncogenes are yielding their place at center stage to a second group of actors, the tumor suppressor genes, which promise to teach us equally important lessons about the molecular ...
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For the past decade, cellular oncogenes have attracted the attention of biologists intent on understanding the molecular origins of cancer. As the present decade unfolds, oncogenes are yielding their place at center stage to a second group of actors, the tumor suppressor genes, which promise to teach us equally important lessons about the molecular ...
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Paragenetic suppressors of suppressor genes - a new class of oncodeterminants
Journal of Cancer Research and Clinical Oncology, 1999Impairment or loss of suppressor genes is a common event permitting the oncogene/suppressor gene machinery to develop neoplasia. Following prenatal treatment with X-rays and UV-B, we detected a new class of oncodeterminants that could not be specified as genes.
J, Roushdy +4 more
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Induction of suppressor cells by a tumor-derived suppressor factor
Cellular Immunology, 1985Murine fibrosarcomas produce a factor that activates suppressor cells to inhibit expression of delayed-type hypersensitivity (DTH) responses to dinitrochlorobenzene (DNCB). This tumor-derived suppressor factor (TDSF) was partially purified by preparative isoelectric focusing of spent medium and 3 M KCl extracts of cultured methylcholanthrene-induced ...
J M, Jessup +3 more
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Annual Review of Biochemistry, 1993
THE ORIGINS OF THE CONCEPT OF TUMOR SUPPRESSOR GENES . . . . . . . 623 THE PROPERTIES OF ONCOGENES AND TUMOR SUPPRESSOR GENES . . 627 THE ONCOGENES OF THE DNA TUMOR VIRUSES TARGET THE MAJOR CELLULAR TUMOR SUPPRESSOR GENES 629 THE RETINOBLASTOMA SUSCEPTIBILITY GENE AND PROTEIN ........
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THE ORIGINS OF THE CONCEPT OF TUMOR SUPPRESSOR GENES . . . . . . . 623 THE PROPERTIES OF ONCOGENES AND TUMOR SUPPRESSOR GENES . . 627 THE ONCOGENES OF THE DNA TUMOR VIRUSES TARGET THE MAJOR CELLULAR TUMOR SUPPRESSOR GENES 629 THE RETINOBLASTOMA SUSCEPTIBILITY GENE AND PROTEIN ........
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