Results 31 to 40 of about 1,053,068 (399)

High DAPK1 Expression Promotes Tumor Metastasis of Gastric Cancer

open access: yesBiology, 2022
Gastric cancer (GC) is a common upper gastrointestinal tumor. Death-associated protein kinase (DAPK1) was found to participate in the development of various malignant tumors. However, there are few reports on DAPK1 in gastric cancer.
Qingshui Wang   +6 more
doaj   +1 more source

Regulating tumor suppressor genes: post-translational modifications

open access: yesSignal Transduction and Targeted Therapy, 2020
Tumor suppressor genes cooperate with each other in tumors. Three important tumor suppressor proteins, retinoblastoma (Rb), p53, phosphatase, and tensin homolog deleted on chromosome ten (PTEN) are functionally associated and they regulated by post ...
Ling Chen, Shuang Liu, Y. Tao
semanticscholar   +1 more source

Mitotic-Spindle Organizing Protein MztA Mediates Septation Signaling by Suppressing the Regulatory Subunit of Protein Phosphatase 2A-ParA in Aspergillus nidulans

open access: yesFrontiers in Microbiology, 2018
The proper timing and positioning of cytokinesis/septation is crucial for hyphal growth and conidiation in Aspergillus nidulans. The septation initiation network (SIN) components are a conserved spindle pole body (SPB) localized signaling cascade and the
Ping Jiang, Shujun Zheng, Ling Lu
doaj   +1 more source

Prediction Of Cancer Possibility By Pattern Recognition And Statistical Study Of Expression Of Gene Level Of Cancer Cells [PDF]

open access: yes, 2011
The activity of the p53 tumor-suppressor protein has a key role in controlling both cancer and aging: under activity encourages the growth of cancer, and over activity can accelerate the aging process.
Devang Odedra, Medhavi Mallick
core   +2 more sources

Is NHEJ a tumor suppressor or an aging suppressor? [PDF]

open access: yesCell Cycle, 2008
Tumor suppressors are longevity assurance genes that ensure early life fitness. Genes are defined as tumor suppressors if their mutation predisposes the animal to cancer (a phenotype-based definition). Tumor suppressors fall into two categories: caretakers and gatekeepers.
openaire   +3 more sources

Analysis of the Plasmid-Based ts-Mutant ΔfabA/pTS-fabA Reveals Its Lethality under Aerobic Growth Conditions That Is Suppressed by Mild Overexpression of desA at a Restrictive Temperature in Pseudomonas aeruginosa

open access: yesMicrobiology Spectrum, 2023
It is uncertain whether PA1610|fabA is essential or dispensable for growth on LB-agar plates under aerobic conditions in Pseudomonas aeruginosa PAO1.
Liyan Tian   +3 more
doaj   +1 more source

Characterization of Curtovirus V2 Protein, a Functional Homolog of Begomovirus V2

open access: yesFrontiers in Plant Science, 2020
Geminiviruses are single-stranded DNA plant viruses with circular genomes packaged within geminate particles. Among the Geminiviridae family, Begomovirus and Curtovirus comprise the two best characterized genera.
Ana P. Luna   +6 more
doaj   +1 more source

Enhancement of Recombinant Protein Production in Transgenic Nicotiana benthamiana Plant Cell Suspension Cultures with Co-Cultivation of Agrobacterium Containing Silencing Suppressors. [PDF]

open access: yes, 2018
We have previously demonstrated that the inducible plant viral vector (CMViva) in transgenic plant cell cultures can significantly improve the productivity of extracellular functional recombinant human alpha-1-antiryspin (rAAT) compared with either a ...
Dandekar, Abhaya M   +3 more
core   +3 more sources

7-Dehydrocholesterol is an endogenous suppressor of ferroptosis.

open access: yesNature, 2021
Ferroptosis is a form of cell death that has received considerable attention not only as a means to eradicate defined tumour entities but also because it provides unforeseen insights into the metabolic adaptation that tumours exploit to counteract ...
F. Freitas   +46 more
semanticscholar   +1 more source

Selective inhibition of T suppressor-cell function by a monosaccharide [PDF]

open access: yes, 1981
Interactions between regulatory T lymphocytes and other cells are assumed to occur at the level of the cell surface. T cells which suppress the generation of specifically effector cells have been described as having antigenic, idiotypic, allotypic and I ...
AA Moscona   +22 more
core   +1 more source

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