Results 31 to 40 of about 880,593 (358)

Hsa_circ_0043278 Inhibits Tumorigenesis and is Downregulated in Colorectal Cancer

Cancer Management and Research, 2021
Jiali Wang,1,2 Tiangong Wang,2 Shiyun Hu,2 Jinyun Li,1 Chao Ni,1 Meng Ye1 1Department of Oncology and Hematology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, People’s Republic of China; 2School of Medicine, Ningbo ...
Wang J, Wang T, Hu S, Li J, Ni C, Ye M
doaj  

Suppressor Analysis Uncovers That MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly in Schizosaccharomyces pombe

G3: Genes, Genomes, Genetics, 2019
The Kinesin-5 motor Cut7 in Schizosaccharomyces pombe plays essential roles in spindle pole separation, leading to the assembly of bipolar spindle. In many organisms, simultaneous inactivation of Kinesin-14s neutralizes Kinesin-5 deficiency.
Masashi Yukawa, Yusuke Yamada, Takashi Toda   +2 more
doaj   +1 more source

Retinoblastoma Protein Paralogs and Tumor Suppression

Frontiers in Genetics, 2022
The retinoblastoma susceptibility gene (RB1) is the first tumor suppressor gene discovered and a prototype for understanding regulatory networks that function in opposition to oncogenic stimuli.
Mauricio Flores, David W. Goodrich
doaj   +1 more source

Selective inhibition of T suppressor-cell function by a monosaccharide [PDF]

, 1981
Interactions between regulatory T lymphocytes and other cells are assumed to occur at the level of the cell surface. T cells which suppress the generation of specifically effector cells have been described as having antigenic, idiotypic, allotypic and I ...
AA Moscona, B Benacerraf, CG Orosz, DH Boldt, DL Peavy, FM Rollwagen, H Lis, IFC McKenzie, J Moss, JE Geltosky, K Eichmann, LA Herzenberg, LB Grabel, LM Nadler, Michael Kramer, RE Rocklin, RM Ferguson, RW Dutton, SH Barondes, T Tada, U Koszinowski, Ulrich H. Koszinowski, VT Marchesi   +22 more
core   +1 more source

Suppression of cytoplasmic incompatibility in the leaf-mining fly Liriomyza sativae with a nuclear Wolbachia insert

Royal Society Open Science
Cytoplasmic incompatibility (CI) drives maternally transmitted endosymbionts such as Wolbachia through insect populations by inducing embryonic mortality when infected males fertilize uninfected females. CI is controlled by Wolbachia cif operons that are
Yuta Ohata, Takafumi N. Sugimoto, Nicky Wybouw, Yohsuke Tagami   +3 more
doaj   +1 more source

Analysis of Pineapple Mealybug Wilt Associated Virus -1 and -2 for Potential RNA Silencing Suppressors and Pathogenicity Factors

Viruses, 2015
Higher plants use RNA silencing to defend against viral infections. As a counter defense, plant viruses have evolved proteins that suppress RNA silencing.
Kishore K. Dey, Wayne B. Borth, Michael J. Melzer, Ming-Li Wang, John S. Hu   +4 more
doaj   +1 more source

Investigation into the impact of integral suppressor configurations on the pressure levels within the suppressor [PDF]

, 2016
This paper reports on an experimental investigation supported by basic modeling in to the performance of an integral suppressor on a low power firearm. A model was developed to determine the pressure within a suppressor chamber using iterative empirical ...
Champion, Stephen M., Duncan, A., Helliker, A.   +2 more
core  

A tip-based source of femtosecond electron pulses at 30keV [PDF]

, 2013
We present a nano-scale photoelectron source, optimized towards ultrashort pulse durations and well-suited for time-resolved diffraction experiments. A tungsten tip, mounted in a suppressor-extractor electrode configuration, allows the generation of 30 ...
Baum, Peter, Ehberger, Dominik, Förster, Michael, Hammer, Jakob, Hoffrogge, Johannes, Hommelhoff, Peter, Krüger, Michael, Stein, Jan-Paul   +7 more
core   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Tumor suppressors: enhancers or suppressors of regeneration? [PDF]

Development, 2013
Tumor suppressors are so named because cancers occur in their absence, but these genes also have important functions in development, metabolism and tissue homeostasis. Here, we discuss known and potential functions of tumor suppressor genes during tissue regeneration, focusing on the evolutionarily conserved tumor suppressors pRb1, p53, Pten and Hippo.
Jason H, Pomerantz, Helen M, Blau
openaire   +2 more sources