Results 11 to 20 of about 641,238 (306)

Dilute suppressor, a new suppressor gene in the house mouse

Journal of Heredity, 1983
Dilute suppressor, dsu, a new fully penetrant autosomal recessive mutation, acts by restoring melanocytes of homozygous dilute (d/d) mice to normal shape and almost normal number. This action creates a nondilute appearing coat color in dilute mice. Dilute suppressor is located on chromosome 1 linked to isocitrate dehydrogenase (Idh-I) with 6.25 +/- 3 ...
Sweet, H O
core   +4 more sources

Binding of small interfering RNA molecules is crucial for RNA interference suppressor activity of rice hoja blanca virus NS3 in plants [PDF]

, 2009
The NS3 protein of rice hoja blanca tenuivirus represents a viral suppressor of RNAi that sequesters small interfering (si)RNAs in vitro. To determine whether this siRNA binding property is the critical determinant for the suppressor activity of NS3, an ...
Kaaij, L., Lohuis, H., Hemmes, J.C., Schnettler, E., Goldbach, R.W., Prins, M.W.   +5 more
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UBE2QL1 is Disrupted by a Constitutional Translocation Associated with Renal Tumor Predisposition and is a Novel Candidate Renal Tumor Suppressor Gene [PDF]

, 2013
Investigation of rare familial forms of renal cell carcinoma (RCC) has led to the identification of genes such as VHL and MET that are also implicated in the pathogenesis of sporadic RCC. In order to identify a novel candidate renal tumor suppressor gene,
Hodgson, S, Morris, Mark R., Turnell, Andrew S., Woodward, ER, Prigmore, Elena, Woodward, Emma R.; id_orcid, Wake, NC, Wake, Naomi C., Gribble, Susan M., Ricketts, Christopher J., Skytte, AB, Brown, Michael, Banks, RE, Morris, MR, Prigmore, E, Maher, ER, Woodward, Emma R., Clarke, Noel, Hodgson, Shirley, Skytte, Anne-bine, Ricketts, CJ, Turnell, AS, Brown, Michael; id_orcid, Maher, Eamonn R., Clarke, N, Banks, Rosamonde E., Gribble, SM, Brown, M, Skytte, Anne Bine, Wake, N, Clarke, Noel W, Brown, Michael D, Ricketts, C, Woodward, E, Skytte, A-B, Maher, E, Morris, M, Banks, R, Turnell, A, Gribble, S   +39 more
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Suppressors of selection

PLOS ONE, 2017
New title, improved presentation, and further examples.
Fernando Alcalde Cuesta, Pablo González Sequeiros, Álvaro Lozano Rojo   +2 more
openaire   +8 more sources

Tumor suppressors: enhancers or suppressors of regeneration? [PDF]

Development, 2013
Tumor suppressors are so named because cancers occur in their absence, but these genes also have important functions in development, metabolism and tissue homeostasis. Here, we discuss known and potential functions of tumor suppressor genes during tissue regeneration, focusing on the evolutionarily conserved tumor suppressors pRb1, p53, Pten and Hippo.
Jason H, Pomerantz, Helen M, Blau
openaire   +2 more sources

Suppressor Mutations in Type II Secretion Mutants of Vibrio cholerae: Inactivation of the VesC Protease

mSphere, 2020
The type II secretion system (T2SS) is a conserved transport pathway responsible for the secretion of a range of virulence factors by many pathogens, including Vibrio cholerae. Disruption of the T2SS genes in V.
Chelsea S. Rule, Young-Jun Park, Jaclyn R. Delarosa, Stewart Turley, Wim G. J. Hol, Sarah McColm, Colby Gura, Frank DiMaio, Konstantin V. Korotkov, Maria Sandkvist   +9 more
doaj   +1 more source

The conversion of amber suppressors to ochre suppressors. [PDF]

Proceedings of the National Academy of Sciences, 1968
Amber suppressors conversion to ochre suppressors in RNA of bacterium or bacteriophage using uracil ...
S, Person, M, Osborn
openaire   +2 more sources

Immune Suppression Mediated by STAT4 Deficiency Promotes Lymphatic Metastasis in HNSCC

Frontiers in Immunology, 2020
Head and neck squamous cell carcinoma (HNSCC) is a prevalent form of cancer with 5-years survival rates around 57%, and metastasis is a leading cause of mortality.
Kelvin Anderson, Nathan Ryan, Greta Volpedo, Greta Volpedo, Sanjay Varikuti, Abhay R. Satoskar, Abhay R. Satoskar, Steve Oghumu   +7 more
doaj   +1 more source

P25 and P37 proteins encoded by firespike leafroll-associated virus are viral suppressors of RNA silencing

Frontiers in Microbiology, 2022
Firespike leafroll-associated virus (FLRaV) is a major pathogen associated with firespike (Odontonema tubaeforme) leafroll disease. Phylogenetic analysis showed that FLRaV possesses typical traits of subgroup II members of ampeloviruses, but encodes two ...
Yaqin Wang, Hui Liu, Zhanqi Wang, Yushuang Guo, Tao Hu, Xueping Zhou, Xueping Zhou   +6 more
doaj   +1 more source

Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1 [PDF]

, 2012
Loss of the tumor suppressor Pdcd4 was reported for various tumor entities and proposed as a prognostic marker in tumorigenesis. We previously characterized decreased Pdcd4 protein stability in response to mitogenic stimuli, which resulted from p70S6K1 ...
Bernhard Brüne, Milke, Larissa, Kathrin Schulz, Larissa Milke, Heidi R Bokesch, Schulz, Kathrin, Colburn, Nancy H., Blees, Johanna, Schmid, Tobias, Curtis J. Henrich (131182), Tobias Schmid, Kathrin Schulz (131170), Magdalena M. Bajer (131176), Heidi R. Bokesch (131163), Bajer, Magdalena M., Daniela Rübsamen (131166), Johanna S Blees, Henrich, Curtis J., Nancy H. Colburn (131186), James B McMahon, Magdalena M Bajer, James B. McMahon (7677), McMahon, James B., Daniela Rübsamen, Kirk R. Gustafson (131179), Tobias Schmid (131190), Nancy H Colburn, Brüne, Bernhard, Kirk R Gustafson, Rübsamen, Daniela, Bernhard Brüne (131193), Curtis J Henrich, Bokesch, Heidi R., Gustafson, Kirk R., Larissa Milke (131173), Johanna S. Blees (131161)   +35 more
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