Results 31 to 40 of about 641,238 (306)

Identification of the Potential Virulence Factors and RNA Silencing Suppressors of Mulberry Mosaic Dwarf-Associated Geminivirus

open access: yesViruses, 2018
Plant viruses encode virulence factors or RNA silencing suppressors to reprogram plant cellular processes or to fine-tune host RNA silencing-mediated defense responses.
Xiuling Yang   +7 more
doaj   +1 more source

Characterization of Curtovirus V2 Protein, a Functional Homolog of Begomovirus V2

open access: yesFrontiers in Plant Science, 2020
Geminiviruses are single-stranded DNA plant viruses with circular genomes packaged within geminate particles. Among the Geminiviridae family, Begomovirus and Curtovirus comprise the two best characterized genera.
Ana P. Luna   +6 more
doaj   +1 more source

Tumor-suppressor-oncogene-scores (TSOS).

open access: yes, 2018
(a) Enrichment analysis using expression derived tumor-suppressor-oncogene-score (TSOS) in human tumors microarray and TCGA/GTEx RNAseq datasets for the whole candidate ortholog gene set (n = 619 and n = 637 respectively) in 1 million random samplings ...
Helena E. Richardson (434920)   +17 more
core   +1 more source

Hsa_circ_0043278 Inhibits Tumorigenesis and is Downregulated in Colorectal Cancer

open access: yesCancer Management and Research, 2021
Jiali Wang,1,2 Tiangong Wang,2 Shiyun Hu,2 Jinyun Li,1 Chao Ni,1 Meng Ye1 1Department of Oncology and Hematology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, People’s Republic of China; 2School of Medicine, Ningbo ...
Wang J, Wang T, Hu S, Li J, Ni C, Ye M
doaj  

Is NHEJ a tumor suppressor or an aging suppressor? [PDF]

open access: yesCell Cycle, 2008
Tumor suppressors are longevity assurance genes that ensure early life fitness. Genes are defined as tumor suppressors if their mutation predisposes the animal to cancer (a phenotype-based definition). Tumor suppressors fall into two categories: caretakers and gatekeepers.
openaire   +2 more sources

Modulation of T-cell function by myeloid-derived suppressor cells in hematological malignancies

open access: yesFrontiers in Cell and Developmental Biology, 2023
Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and monocytes that negatively regulate the immune response to cancer and chronic infections.
Vaishali Bhardwaj, Stephen M. Ansell
doaj   +1 more source

Suppressor Analysis Uncovers That MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly in Schizosaccharomyces pombe

open access: yesG3: Genes, Genomes, Genetics, 2019
The Kinesin-5 motor Cut7 in Schizosaccharomyces pombe plays essential roles in spindle pole separation, leading to the assembly of bipolar spindle. In many organisms, simultaneous inactivation of Kinesin-14s neutralizes Kinesin-5 deficiency.
Masashi Yukawa   +2 more
doaj   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham   +7 more
wiley   +1 more source

Suppression of cytoplasmic incompatibility in the leaf-mining fly Liriomyza sativae with a nuclear Wolbachia insert

open access: yesRoyal Society Open Science
Cytoplasmic incompatibility (CI) drives maternally transmitted endosymbionts such as Wolbachia through insect populations by inducing embryonic mortality when infected males fertilize uninfected females. CI is controlled by Wolbachia cif operons that are
Yuta Ohata   +3 more
doaj   +1 more source

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim   +11 more
wiley   +1 more source

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