Results 21 to 30 of about 641,238 (306)

Mitotic-Spindle Organizing Protein MztA Mediates Septation Signaling by Suppressing the Regulatory Subunit of Protein Phosphatase 2A-ParA in Aspergillus nidulans

open access: yesFrontiers in Microbiology, 2018
The proper timing and positioning of cytokinesis/septation is crucial for hyphal growth and conidiation in Aspergillus nidulans. The septation initiation network (SIN) components are a conserved spindle pole body (SPB) localized signaling cascade and the
Ping Jiang, Shujun Zheng, Ling Lu
doaj   +1 more source

Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter [PDF]

open access: yes, 2010
The cytokine TGF-beta acts as a tumor suppressor in normal epithelial cells and during the early stages of tumorigenesis. During malignant progression, cancer cells can switch their response to TGF-beta and use this cytokine as a potent oncogenic factor;
Hiller, L   +130 more
core   +1 more source

High DAPK1 Expression Promotes Tumor Metastasis of Gastric Cancer

open access: yesBiology, 2022
Gastric cancer (GC) is a common upper gastrointestinal tumor. Death-associated protein kinase (DAPK1) was found to participate in the development of various malignant tumors. However, there are few reports on DAPK1 in gastric cancer.
Qingshui Wang   +6 more
doaj   +1 more source

Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells [PDF]

open access: yes, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Note: In this manuscript as well as in the original published version of this article the word "Polyphenon" was incorrectly spelled in the title as ...
Chayka, O   +10 more
core   +1 more source

Suppressor genes as molecular markers of colorectal cancer – a review of the latest reports

open access: yes, 2020
Suppressor gene research is one of the main current trends in modern cancer research. Oncogenesis, including colorectal cancer (CRC), is a process strictly dependent on the proper functioning of the suppressor genes and their proteins.
Stanisław Głuszek   +3 more
core   +1 more source

Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT [PDF]

open access: yes, 2016
Myosin-1C (MYO1C) is a tumor suppressor candidate located in a region of recurrent losses distal to TP53. Myo1c can tightly and specifically bind to PIP2, the substrate of Phosphoinositide 3-kinase (PI3K), and to Rictor, suggesting a role for MYO1C in ...
Ejeskar, K.,   +63 more
core   +2 more sources

Interaction of UAG suppressors and omnipotent suppressors in Saccharomyces cerevisiae [PDF]

open access: yesJournal of Bacteriology, 1985
Haploids bearing the dominant UAG suppressor, SUP7-a, and various alleles of the omnipotent suppressor sup35 were examined. The presence of the UAG suppressor reduced the efficiency of some alleles of sup35, and caused other sup35 alleles to be lethal.
J M, Song, S W, Liebman
openaire   +2 more sources

The role of the tumor suppressor CYLD in Yersinia enterocolitica infection [PDF]

open access: yes, 2012
Recent studies have identified the tumor suppressor CYLD as a key regulator of NF -κB, a transcription factor that promotes cell survival and oncogenesis, as well as host defence to infection.
Liu, Yunying
core   +1 more source

Copper Underpotential Deposition on Gold in the Presence of Polyethylene Glycol and Chloride

open access: yesInternational Journal of Electrochemical Science, 2011
Many articles have shown that polyethylene glycol (PEG), when combined with chloride ions, is a strong suppressor of copper overpotential deposition (OPD) on a copper substrate.
Yong-Da Chiu   +5 more
doaj   +1 more source

Analysis of the Plasmid-Based ts-Mutant ΔfabA/pTS-fabA Reveals Its Lethality under Aerobic Growth Conditions That Is Suppressed by Mild Overexpression of desA at a Restrictive Temperature in Pseudomonas aeruginosa

open access: yesMicrobiology Spectrum, 2023
It is uncertain whether PA1610|fabA is essential or dispensable for growth on LB-agar plates under aerobic conditions in Pseudomonas aeruginosa PAO1.
Liyan Tian   +3 more
doaj   +1 more source

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