Results 41 to 50 of about 817,665 (309)

Modulation of T-cell function by myeloid-derived suppressor cells in hematological malignancies

Frontiers in Cell and Developmental Biology, 2023
Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and monocytes that negatively regulate the immune response to cancer and chronic infections.
Vaishali Bhardwaj, Stephen M. Ansell
doaj   +1 more source

NF2/merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations. [PDF]

, 2013
Inactivating germline mutations in the tumor suppressor gene NF2 cause the hereditary syndrome neurofibromatosis 2, which is characterized by the development of neoplasms of the nervous system, most notably bilateral vestibular schwannoma.
Angelo, Laura S, Kurzrock, Razelle, Schroeder, Rebecca Dunbar   +2 more
core   +3 more sources

Suppressor Analysis Uncovers That MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly in Schizosaccharomyces pombe

G3: Genes, Genomes, Genetics, 2019
The Kinesin-5 motor Cut7 in Schizosaccharomyces pombe plays essential roles in spindle pole separation, leading to the assembly of bipolar spindle. In many organisms, simultaneous inactivation of Kinesin-14s neutralizes Kinesin-5 deficiency.
Masashi Yukawa, Yusuke Yamada, Takashi Toda   +2 more
doaj   +1 more source

Selective inhibition of T suppressor-cell function by a monosaccharide [PDF]

, 1981
Interactions between regulatory T lymphocytes and other cells are assumed to occur at the level of the cell surface. T cells which suppress the generation of specifically effector cells have been described as having antigenic, idiotypic, allotypic and I ...
AA Moscona, B Benacerraf, CG Orosz, DH Boldt, DL Peavy, FM Rollwagen, H Lis, IFC McKenzie, J Moss, JE Geltosky, K Eichmann, LA Herzenberg, LB Grabel, LM Nadler, Michael Kramer, RE Rocklin, RM Ferguson, RW Dutton, SH Barondes, T Tada, U Koszinowski, Ulrich H. Koszinowski, VT Marchesi   +22 more
core   +1 more source

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11 [PDF]

, 2005
Background: Loss of chromosome 11q defines a subset of high-stage aggressive neuroblastomas. Deletions are typically large and mapping efforts have thus far not lead to a well defined consensus region, which hampers the identification of positional ...
De Preter, K, Vandesompele, J, Menten, B, Carr, P, Fiegler, H, Edsjö, Anders,, Carter, NP, Yigit, N, Waelput, W, Van Roy, N, Bader, S, Påhlman, Sven,, Speleman, F, Lund University.   +13 more
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Retinoblastoma Protein Paralogs and Tumor Suppression

Frontiers in Genetics, 2022
The retinoblastoma susceptibility gene (RB1) is the first tumor suppressor gene discovered and a prototype for understanding regulatory networks that function in opposition to oncogenic stimuli.
Mauricio Flores, David W. Goodrich
doaj   +1 more source

Investigation into the impact of integral suppressor configurations on the pressure levels within the suppressor [PDF]

, 2016
This paper reports on an experimental investigation supported by basic modeling in to the performance of an integral suppressor on a low power firearm. A model was developed to determine the pressure within a suppressor chamber using iterative empirical ...
Champion, Stephen M., Duncan, A., Helliker, A.   +2 more
core  

Suppression of cytoplasmic incompatibility in the leaf-mining fly Liriomyza sativae with a nuclear Wolbachia insert

Royal Society Open Science
Cytoplasmic incompatibility (CI) drives maternally transmitted endosymbionts such as Wolbachia through insect populations by inducing embryonic mortality when infected males fertilize uninfected females. CI is controlled by Wolbachia cif operons that are
Yuta Ohata, Takafumi N. Sugimoto, Nicky Wybouw, Yohsuke Tagami   +3 more
doaj   +1 more source

Tumor suppressors: enhancers or suppressors of regeneration? [PDF]

Development, 2013
Tumor suppressors are so named because cancers occur in their absence, but these genes also have important functions in development, metabolism and tissue homeostasis. Here, we discuss known and potential functions of tumor suppressor genes during tissue regeneration, focusing on the evolutionarily conserved tumor suppressors pRb1, p53, Pten and Hippo.
Jason H, Pomerantz, Helen M, Blau
openaire   +2 more sources

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context [PDF]

, 2018
Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling ...
Abdel-Rahman, Mohamed H., Abeshouse, Adam, Adebamowo, Clement, Adebamowo, Sally N., Agnew, Kathy, Ahn, Keunsoo, Ajani, Jaffer A., Akbani, Rehan, Akeredolu, Teniola, Al-Ahmadie, Hikmat, Albert, Monique, Alexopoulou, Iakovina, Ally, Adrian, Alvaro, Domenico, Anderson, Matthew L., Andry, Chris, Antenucci, Anna, Anur, Pavana, Appelbaum, Elizabeth L., Aredes, Natália D., Armenia, Joshua, Arnaout, Angel, Asa, Sylvia L., Auman, J. Todd, Aymerich, Marta, Aziz, Dina, Bailey, Matthew, Balasundaram, Miruna, Balu, Saianand, Barnett, Gene, Barnholtz-Sloan, Jill S., Barrett, Wendi, Bartlett, John, Bathe, Oliver, Baudin, Eric, Baylin, Stephen, Becker, Karl-Friedrich, Beer, David, Behera, Madhusmita, Behrens, Carmen, Bell, Debra, Bell, Sue, Bellair, Michelle, Bennett, Joseph, Benz, Christopher, Berchuck, Andrew, Berger, Ashton C., Bergeron, Alain, Berkowitz, Ross, Bernard, Brady, Beroukhim, Rameen, Beuschlein, Felix, Bifulco, Carlo, Bigner, Darell, Birrer, Michael, Birsoy, Kivanc, Bocklage, Therese, Bodenheimer, Tom, Bondaruk, Jolanta, Bootwalla, Moiz S., Borad, Mitesh, Borgia, Jeffrey A., Bossler, Aaron, Botnariuc, Natalia, Boussioutas, Alex, Bowen, Jay, Bowlby, Reanne, Bowman, Rayleen, Bradford, Carol, Bragazzi, Maria Consiglia, Brat, Daniel J., Breggia, Anne, Brewer, Cathy, Brimo, Fadi, Broaddus, Russell, Brooks, Denise, Broom, Bradley M., Broudy, Thomas, Bryce, Alan H., Bubley, Glenn, Bueno, Raphael, Burnette, Andrew, Caesar-Johnson, Samantha J., Calatozzolo, Chiara, Campo, Elias, Campos, Benito, Caraman, Irina, Cardinale, Vincenzo, Carey, Francis, Carey, Thomas, Carlotti, Carlos Gilberto, Carlsen, Rebecca, Carney, Michael, Carpino, Guido, Carroll, Peter R., Carter, Candace, Carvalho, Andre L., Castle, Erik, Castro, Patricia D., Catto, James, Cebulla, Colleen M., Cernat, Mircea, Chabot, John, Chakravarty, Debyani, Chambwe, Nyasha, Chan, June M., Chan, Timothy A., Chandan, Vishal, Chang, Kyle, Chatila, Walid K., Chatterjee, Sujash S., Chemencedji, Inga, Chen, Amy, Chen, Chu, Chen, Ting-Wen, Cheng, Feixiong, Cherniack, Andrew D., Chesla, David, Chevalier, Simone, Cheville, John, Chiu, Hua-Sheng, Cho, Juok, Chuah, Eric, Chudamani, Sudha, Chung, Ki, Cibulskis, Carrie, Clipca, Adrian, Colman, Howard, Cope, Leslie, Copland, John A., Corcoran, Niall, Cordes, Matthew G., Costello, Tony, Cottingham, Sandra, Couce, Marta, Covington, Kyle, Crain, Daniel, Cramer, Daniel, Creaney, Jenette, Creighton, Chad J., Cuppini, Lucia, Curley, Erin, Cuzzubbo, Stefania, Czerniak, Bogdan, Danilova, Ludmila, Davis, Amy, de Bruijn, Ino, de Carvalho, Ana C., de Krijger, Ronald, De Rienzo, Assunta, De Rose, Agostino, Defreitas, Timothy, Delman, Keith, Demchok, John A., Desjardins, Laurence, Devine, Karen, Deyarmin, Brenda, Dhalla, Noreen, Dhanasekaran, Renumathy, Dhankani, Varsha, Dhir, Rajiv, Dimeco, Francesco, Ding, Li, Dinh, Huyen, Dinkin, Mikhail, Dipersio, John, Disaia, Philip, Doddapaneni, Harshavardhan, Donehower, Lawrence A., Doruc, Serghei, Dos Santos, Jose Sebastião, Dottino, Peter R., Drake, Bettina, Drummond, Jennifer, Drwiega, Paul, Dubina, Michael, Duell, Rebecca, Duffy, Elizabeth R., Eckman, John, Edenfield, W. Jeffrey, Eijckenboom, Wil, Elder, J. Bradley, Engel, Jay, Eschbacher, Jennifer, Esmaeli, Bita, Evason, Kimberley, Facciolo, Francesco, Fan, Cheng, Fan, Huihui, Fantacone-Campbell, J. Leigh, Farnell, Michael, Farver, Carol, Fassnacht, Martin, Fehrenbach, Ashley, Felau, Ina, Feldman, Michael, Feltmate, Colleen, Ferguson, Martin L., Finocchiaro, Gaetano, Flotte, Thomas, Fong, Kwun M., Force, Seth, Forgie, Ian, Frazer, Scott, Fregnani, José H., Fronick, Catrina C., Fujimoto, Junya, Fulop, Jordonna, Fulton, Lucinda A., Fulton, Robert S., Gabra, Hani, Gabriel, Stacey B., Galbraith, Joseph, Gao, Galen F., Gao, Jianjiong, Gardner, Johanna, Gastier-Foster, Julie M., Gaudio, Eugenio, Gehlenborg, Nils, Gerken, Mark, Gershenwald, Jeffrey, Getz, Gad, Ghossein, Ronald, Giama, Nasra, Gibbs, Richard A., Gilbert, Sebastien, Gillis, Ad, Gimenez-Roqueplo, Anne-Paule, Giné, Eva, Giordano, Thomas, Girard, Nicolas, Giuliante, Felice, Glenn, Pat, Glenn, Robert, Godwin, Andrew K., Godwin, Eryn M., Gonzalez, Ana Maria Angulo, Goodman, Marc, Gopalan, Anuradha, Goparaju, Chandra, Gorincioi, Ghenadie, Govindan, Ramaswamy, Graefen, Markus, Grazi, Gianluca, Grizzle, William E., Gross, Benjamin E., Guillermo, Armando López, Gunaratne, Preethi H., Guo, Charles, Ha, Gavin, Haddad, Andrea, Hagedorn, Curt H., Hale, Walker, Han, Yi, Hanh, Phan Thi, Hansen, Paul, Harr, Jodi, Hartmann, Arndt, Haydu, Lauren, Hayes, D. Neil, Hayward, Nicholas, Heath, Sharon, Hegde, Apurva M., Heiman, David I., Heins, Zachary J., Henderson, Joel, Hermes, Beth, Hernandez, Brenda, Herold-Mende, Christel, Hersey, Peter, Hess, Julian, Hibshoosh, Hanina, Hilty, Joe, Hinoue, Toshinori, Ho, Thai, Hoadley, Katherine A., Holt, Robert, Hooke, Jeffrey A., Hoon, Dave, Horowitz, Neil, Houck, John, Hovens, Christopher, Hoyle, Alan P., Hu, Hai, Hu, Jianhong, Huland, Hartwig, Hung, Nguyen Phi, Huntsman, David, Hutter, Carolyn M., Iacocca, Mary, Ittmann, Michael, Jacobus, Laura, Jakrot, Valerie, Janssen, Klaus-Peter, Jefferys, Stuart R., Jimeno, Antonio, Jones, Corbin D., Jones, Steven J. M., Ju, Zhenlin, Juhl, Hartmut, Jungk, Christin, Junker, Kerstin, Kakavand, Hojabr, Kalkanis, Steven, Kanchi, Rupa S., Kandoth, Cyriac, Kang, Koo Jeong, Karlan, Beth Y., Kasaian, Katayoon, Kasapi, Melpomeni, Kastl, Alison, Kebebew, Electron, Kefford, Richard, Kelley, Robin K., Kemp, Rafael, Kendall, Sara, Kendler, Ady, Kendrick, Michael, Khuri, Fadlo, Kibel, Adam, Kim, Jaegil, Knijnenburg, Theo, Knudson, Michael, Knutson, Tina, Kocher, Jean-Pierre, Kohl, Bernard, Kopp, Karla, Korchina, Viktoriya, Korkut, Anil, Korpershoek, Esther, Korst, Robert, Kovatich, Albert J., Kramer, Roger, Kucherlapati, Melanie H., Kucherlapati, Raju S., Kumar, Bahavna, Kundra, Ritika, Kvecher, Leonid, Kycler, Witold, La, Konnor, Lacombe, Louis, Ladanyi, Marc, Lai, Phillip H., Laird, Peter W., Landen, Charles N., Landrum, Lisa, Lang, James, Larson, Caroline, Latour, Mathieu, Lau, Kevin, Lawrence, Michael S., Lazar, Alexander J., Le, Xuan, Lechan, Ronald, Lee, Darlene, Lee, Jung Il, Lee, Kenneth, Lee, Sandra, Lehman, Norman L., Leinonen, Kalle, Leraas, Kristen M., Levine, Douglas A., Lewis, Lora, Ley, Timothy, Li, Jun, Li, Wei, Liang, Han, Lichtenberg, Tara M., Lin, Pei, Linehan, W. Marston, Ling, Shiyun, Lipp, Eric, Liptay, Michael J., Liu, Jia, Liu, Wenbin, Liu, Xiuping, Liu, Yuexin, Logothetis, Christopher, Lohavanichbutr, Pawadee, Lolla, Laxmi, Long, Georgina, Longatto-Filho, Adhemar, Looijenga, Leendert, Lu, Yiling, Luketich, James, Luna, Augustin, Lyadov, Vladimir, Ma, Deqin, Ma, Yussanne, Madan, Rashna, Maglinte, Dennis T., Magliocca, Kelly, Maithel, Shishir, Mallery, David, Malykh, Andrei, Mandt, Randy, Manikhas, George, Mann, Graham, Mannel, Robert, Mannelli, Massimo, Mardis, Elaine R., Mariamidze, Armaz, Mariani, Odette, Marino, Mirella, Marks, Jeffrey, Marra, Marco A., Martignetti, John A., Martin, Julie, Mattei, Luca, Mayo, Michael, Mccall, Shannon, Mcgraw, Mary, Mckercher, Ginette, Mclellan, Michael D., Mclendon, Roger, Mcpherson, Christopher, Meier, Sam, Melamed, Jonathan, Meng, Shaowu, Meric-Bernstam, Funda, Merola, Roberta, Mes-Masson, Anne-Marie, Metwalli, Adam R., Meyerson, Matthew, Mieczkowski, Piotr A., Mikkelsen, Tom, Milhem, Mohammed, Miller, Christopher A., Miller, Judy, Miller, Michael, Mills, Gordon B., Mirsaidi, Cyrus, Moiseenko, Fedor, Moncrieff, Marc, Moore, Kathleen, Moore, Richard A., Moran, Cesar, Morgan, Margaret, Morris, Scott, Morrison, Carl, Morton, Donna, Mose, Lisle E., Moser, Catherine, Moxley, Katherine, Moyer, Jeffey, Mungall, Andrew J., Mungall, Karen, Mura, Sergiu, Mural, Richard J., Murawa, Dawid, Muto, Michael, Muzny, Donna, Myers, Jerome, Nagorney, David, Nair, Praveen, Naresh, Rashi, Naska, Theresa, Nelson, Mark, Ng, Kwok-Shing, Nguyen, Phuong, Nissan, Moriah G., Noble, Michael S., Noss, Ardene, Noushmehr, Houtan, O'Brien, Daniel, O'Neill, Brian Patrick, Ochoa, Angelica, Olabode, Oluwole, Olson, Jeffrey J., Omberg, Larsson, Oosterhuis, Wolter, Ostrom, Quinn T., Owonikoko, Taofeek, Pacak, Karel, Paklina, Oxana, Pan, Yinghong, Parfitt, Jeremy, Park, Joong-Won, Parker, Joel S., Pass, Harvey, Patel, Ektaben, Patel, Tushar, Patil, Sagar L., Paulauskis, Joseph, Pennell, Nathan A., Penny, Robert, Perin, Alessandro, Perou, Amy H., Perou, Charles M., Petersen, Gloria, Peterson, Lisa, Peto, Myron, Phillips, Joanna, Phillips, Sarah M., Phu, Bui Duc, Piché, Alain, Pickens, Alan, Pihl, Todd, Pilarski, Robert, Pinero, Edna M. Mora, Pinto, Peter A., Pirtac, Maria, Pollo, Bianca, Pool, Mark, Porten, Sima, Postier, Russel, Potapova, Olga, Powers, James, Prados, Michael, Prince, Mark, Que, Florencia, Quinn, Michael, Quintero-Aguilo, Mario, Rabeno, Brenda, Rai, Karan, Ramalingam, Suresh, Ramirez, Nilsa C., Ramondetta, Lois, Rao, Arvind, Rassl, Doris M., Rathmell, W. Kimryn, Raut, Chandrajit P., Raymond, Daniel, Reis, Rui M., Reuter, Victor, Reynolds, Sheila, Reznik, Ed, Rice, David, Richards, William G., Rintoul, Robert C., Rivera, Michael, Roach, Jeffrey, Roberts, Lewis, Robertson, A. Gordon, Robinson, Bruce, Roggin, Kevin, Roman-Roman, Sergio, Rosenthal, Howard G., Rozek, Laura, Rubin, Mark A., Ryan, Michael, Saad, Fred, Sadeghi, Sara, Saksena, Gordon, Sanchez-Vega, Francisco, Sander, Chris, Sankarankuty, Ajith, Santibanez, Jireh, Sastre, Xavier, Sauter, Guido, Saw, Robyn, Scapulatempo-Neto, Cristovam, Scarpace, Lisa, Schadendorf, Dirk, Schein, Jacqueline E., Schiffman, Mark, Schilero, Cathy, Schlomm, Thorsten, Schmidt, Heather K., Schmidt, Laura S., Schoenfield, Lynn, Schultz, Nikolaus, Schumacher, Steven E., Scolyer, Richard, Secord, Angeles, Seder, Christopher W., Sekhon, Harman, Senecal, Kelly, Sepulveda, Antonia, Setdikova, Galiya, Sexton, Katherine C., Shabunin, Alexey, Shannon, Kerwin, Sharp, Alexis, Shelley, Carl Simon, Shelton, Candace, Shelton, Troy, Shen, Hui, Sheridan, Robert, Sherman, Mark, Sheth, Margi, Shi, Yan, Shih, Juliann, Shimmel, Kristen, Shin, Dong M., Shinbrot, Eve, Shipman, Cassaundra, Shmulevich, Ilya, Shriver, Craig D., Sica, Gabriel, Sifri, Suzanne, Sigmund, Rita, Signoretti, Sabina, Silveira, Henrique C. S., Simko, Jeffry, Simon, Ronald, Simons, Janae V., Singer, Samuel, Singh, Bhuvanesh, Singh, Rosy, Singh, Vivek P., Sipahimalani, Payal, Skelly, Tara, Sloan, Andrew E., Slotta-Huspenina, Julia, Smallridge, Robert, Smith, Jennifer, Smith-McCune, Karen, Smolenski, Kathy, Smyrk, Thomas, Sofia, Heidi J., Soloway, Matthew G., Somiari, Stella, Somvanshi, Sonal, Sood, Anil, Sood, Anil K., Spellman, Paul, Spillane, Andrew, Stancul, Irina, Stanton, Melissa, Staugaitis, Susan M., Steele, Ruth, Stepa, Serghei, Stern, Marc-Henri, Stoehr, Christine, Stoehr, Robert, Stoop, Hans, Stretch, Jonathan, Stuart, Joshua M., Su, Tao, Sumazin, Pavel, Sumer, S. Onur, Sun, Qiang, Sun, Yichao, Swanson, Patricia, Swisher, Elizabeth, Synott, Maria, Tam, Angela, Tamakawa, Raina, Tamboli, Pheroze, Tan, Donghui, Tang, Yufang, Tarnuzzer, Roy, Taubert, Helge, Tavobilov, Mikhail, Taylor, Barry S., Tcaciuc, Diana, Tennstedt, Pierre, Thiessen, Nina, Thomas, George, Thompson, Eric, Thompson, John, Thompson, R. Houston, Thompson, Timothy, Thorp, Richard, Thorsson, Vesteinn, Tien, Nguyen Viet, Timmers, Henri, Tirapelli, Daniela, Tischler, Arthur, Torbenson, Michael, Troncoso, Patricia, Tsao, Anne, Tse, Kane, Tucker, Kelinda, Têtu, Bernard, Unterberg, Andreas, Urba, Walter, Valdivieso, Federico, Van Bang, Nguyen, Van Den Berg, David J., van Kessel, Kim E., Van Meir, Erwin G., Van Tine, Brian, Vandenberg, Scott, Veluvolu, Umadevi, Vicha, Ales, Vidal, Daniel O., Vocke, Cathy D., Voet, Doug, von Deimling, Andreas, Voronina, Olga, Wach, Sven, Wakely, Paul, Waldmann, Jens, Walker, Joan, Wan, Yunhu, Wang, Jing, Wang, Jioajiao, Wang, Linghua, Wang, Min, Wang, Timothy, Wang, Zhining, Warnick, Ronald, Weinstein, John N., Weisenberger, Daniel J., Wentzensen, Nicolas, Westervelt, Peter, Wheeler, David A., Wilkerson, Matthew D., Williams, Felicia, Wilmott, James, Wilson, Richard K., Wise, Lisa, Wistuba, Ignacio, Wiznerowicz, Maciej, Wolf, Gregory, Wolinsky, Yingli, Wong, Christopher K., Wong, Tina, Worrell, Robert, Wu, Ye, Wullich, Bernd, Xi, Liu, Yang, Hannah, Yang, Ian, Yang, Ju Dong, Yang, Liming, Yau, Christina, Yena, Peggy, Zach, Leigh Anne, Zaren, Howard, Zelinka, Tomas, Zenklusen, Jean C., Zhang, Hailei, Zhang, Hongxin, Zhang, Hongzheng, Zhang, Jiashan (Julia), Zhang, Jiexin, Zhang, Lizhi, Zhang, Wei, Zhao, Fengmei, Zhou, Wanding, Zmuda, Erik, Zorman, Barry, Zuna, Rosemary, Zwarthoff, Ellen C.   +736 more
core   +3 more sources