Results 41 to 50 of about 1,053,068 (399)
Viruses, 2018 Plant viruses encode virulence factors or RNA silencing suppressors to reprogram plant cellular processes or to fine-tune host RNA silencing-mediated defense responses.
Xiuling Yang +7 more
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Modulation of T-cell function by myeloid-derived suppressor cells in hematological malignancies
Frontiers in Cell and Developmental Biology, 2023 Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and monocytes that negatively regulate the immune response to cancer and chronic infections.
Vaishali Bhardwaj, Stephen M. Ansell
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Hsa_circ_0043278 Inhibits Tumorigenesis and is Downregulated in Colorectal Cancer
Cancer Management and Research, 2021 Jiali Wang,1,2 Tiangong Wang,2 Shiyun Hu,2 Jinyun Li,1 Chao Ni,1 Meng Ye1 1Department of Oncology and Hematology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, People’s Republic of China; 2School of Medicine, Ningbo ...
Wang J, Wang T, Hu S, Li J, Ni C, Ye M
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NF2/merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations. [PDF]
, 2013 Inactivating germline mutations in the tumor suppressor gene NF2 cause the hereditary syndrome neurofibromatosis 2, which is characterized by the development of neoplasms of the nervous system, most notably bilateral vestibular schwannoma.
Angelo, Laura S +2 more
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Interaction of UAG suppressors and omnipotent suppressors in Saccharomyces cerevisiae [PDF]
Journal of Bacteriology, 1985 Haploids bearing the dominant UAG suppressor, SUP7-a, and various alleles of the omnipotent suppressor sup35 were examined. The presence of the UAG suppressor reduced the efficiency of some alleles of sup35, and caused other sup35 alleles to be lethal.
S. W. Liebman, Jae Mahn Song
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Networks of tumor suppressors [PDF]
EMBO reports, 2000 Sponsored by the Juan March Foundation, and organized by J Massague and M Serranno. Madrid, Spain, May 8–10, 2000. ![][1] The concept of tumor suppressor networks comes as a logical consequence of the increasing understanding of the biology of tumor suppressor genes and oncogenes. Indeed, it has been gratifying to realize during the past decade that
Joan Massagué, Manuel Serrano
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G3: Genes, Genomes, Genetics, 2019 The Kinesin-5 motor Cut7 in Schizosaccharomyces pombe plays essential roles in spindle pole separation, leading to the assembly of bipolar spindle. In many organisms, simultaneous inactivation of Kinesin-14s neutralizes Kinesin-5 deficiency.
Masashi Yukawa +2 more
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The NS3 protein of rice hoja blanca virus suppresses RNA silencing in mammalian cells [PDF]
, 2008 The NS3 protein of the tenuivirus rice hoja blanca virus (RHBV) has previously been shown to represent the viral RNA interference (RNAi) suppressor and is active in both plant and insect cells by binding short interfering RNAs (siRNAs) in vitro.
Goldbach, R.W. +3 more
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Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression
British Journal of Cancer, 2018 Under steady-state conditions, bone marrow-derived immature myeloid cells (IMC) differentiate into granulocytes, macrophages and dendritic cells (DCs). This differentiation is impaired under chronic inflammatory conditions, which are typical for tumour ...
Christopher Groth +6 more
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At the double for tumor suppressor [PDF]
eLife, 2016 Research on zebrafish reveals how a tumor suppressor works in two different types of cells, and how hypotonic stress promotes tumor formation when the function of this tumor suppressor is lost.
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