Results 51 to 60 of about 1,053,068 (399)
A tip-based source of femtosecond electron pulses at 30keV [PDF]
, 2013 We present a nano-scale photoelectron source, optimized towards ultrashort pulse durations and well-suited for time-resolved diffraction experiments. A tungsten tip, mounted in a suppressor-extractor electrode configuration, allows the generation of 30 ...
Baum, Peter +7 more
core +3 more sources
A Tumor Suppressor SIRTainty [PDF]
Cancer Cell, 2010 Sirtuin deacetylases are linked to longevity, aging, and stress responses. In this issue of Cancer Cell, Kim et al. show that SIRT3 functions as a tumor suppressor by enhancing the expression of mitochondrial MnSOD. Loss of SIRT3 leads to increased mitochondrial ROS, which then enhances cellular transformation and tumor growth.
openaire +3 more sources
Retinoblastoma Protein Paralogs and Tumor Suppression
Frontiers in Genetics, 2022 The retinoblastoma susceptibility gene (RB1) is the first tumor suppressor gene discovered and a prototype for understanding regulatory networks that function in opposition to oncogenic stimuli.
Mauricio Flores, David W. Goodrich
doaj +1 more source
Does Notch play a tumor suppressor role across diverse squamous cell carcinomas? [PDF]
, 2016 The role of Notch pathway in tumorigenesis is highly variable. It can be tumor suppressive or pro-oncogenic, typically depending on the cellular context.
Biswas, Sangita +5 more
core +1 more source
Royal Society Open ScienceCytoplasmic incompatibility (CI) drives maternally transmitted endosymbionts such as Wolbachia through insect populations by inducing embryonic mortality when infected males fertilize uninfected females. CI is controlled by Wolbachia cif operons that are
Yuta Ohata +3 more
doaj +1 more source
Mosquito-Borne Viruses and Suppressors of Invertebrate Antiviral RNA Silencing
Viruses, 2014 The natural maintenance cycles of many mosquito-borne viruses require establishment of persistent non-lethal infections in the invertebrate host. While the mechanisms by which this occurs are not well understood, antiviral responses directed by small ...
Scott T. O'Neal +3 more
doaj +1 more source
Investigation into the impact of integral suppressor configurations on the pressure levels within the suppressor [PDF]
, 2016 This paper reports on an experimental investigation supported by basic modeling in to the performance of an integral suppressor on a low power firearm. A model was developed to determine the pressure within a suppressor chamber using iterative empirical ...
Champion, Stephen M. +2 more
core
Nature Reviews Neuroscience, 2017 Calcitonin gene-related peptide-expressing neurons in the external parabrachial nucleus can drive cancer-induced anorexia in mice.
openaire +3 more sources
Infection Models for Pine Wilt Disease on the Basis of Vector Behaviors
Population Ecology, EarlyView.Infection models for pine wilt disease without vector density were built to estimate the transmission coefficient of the pathogenic nematode. The models successfully simulated the annual change in the density of infected trees for four pine stands. ABSTRACT Pine wilt disease is caused by the pinewood nematode (Bursaphelenchus xylophilus Steiner et ...
Katsumi Togashi
wiley +1 more source
Role of Oncogenes and Tumor-suppressor Genes in Carcinogenesis: A Review
Anticancer Research, 2020 Cancer is a medical condition which has a molecular basis. Proto-oncogenes are the first regulatory factors of this biological process. They act in transmitting signals, resulting as growth factors. Modifications of these genes, called oncogenes, lead to
E. Kontomanolis +11 more
semanticscholar +1 more source