Results 221 to 230 of about 189,911 (333)

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Prostate Cancer, JAK/STAT3 Dysregulation, and Flavonoids: Is There a Possible Link? [PDF]

Int J Mol Sci
Uivarosi V, Miricescu D, Vacaroiu IA, Spinu DA, Stefani C, Stanciu S, Nica RI, Stanescu-Spinu II, Badoiu SC, Nica S, Jinga V.   +10 more
europepmc   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

IL-37/IL-1R8 axis: a novel major mechanism of control at the interface between tumor and immune cells. [PDF]

Oncoimmunology
Landolina N, Mariotti FR, Munari E, Tumino N, Vacca P, Azzarone B, Moretta L, Maggi E.   +7 more
europepmc   +1 more source

Suppressor of Cytokine Signaling 3 Inhibits Antiviral IFN-β Signaling To Enhance HIV-1 Replication in Macrophages

Journal of Immunology, 2010
Lisa N Akhtar, H. Qin, Michelle T. Muldowney, L. Yanagisawa, O. Kutsch, J. Clements, E. Benveniste   +6 more
semanticscholar   +1 more source

Turmeric (Curcuma longa) extract enhances fibroblast growth factor 21 (FGF21) sensitivity and mitigates suppressor of cytokine signaling protein-3 (SOCS-3)-induced insulin resistance in type 2 diabetic rats

Science World Journal
Type 2 diabetes mellitus (T2DM) is a disorder characterized by insulin resistance, hyperglycemia, and inflammation. Fibroblast growth factor 21 (FGF21) plays a crucial role in glucose and lipid metabolism but is often dysregulated in T2DM due to FGF21 resistance, linked to reduced β-Klotho expression.
Ladan, Bilkisu Mohammed, Irene, Agboola Omolara, Bako, Hauwa'u Yakubu, Auta, Richard, Mohammed, Zainab Kasim, Mohammed, Jaafaru Sani, Yakubu, Aliyu   +6 more
openaire   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

The Dual Role of A20 (TNFAIP3) in Viral Infection: A Context-Dependent Regulator of Immunity and Pathogenesis. [PDF]

Viruses
Jeon H, Lee C.
europepmc   +1 more source

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

Cbl promotes MyD88 ubiquitin-mediated degradation in macrophages via phosphorylation and calcium mobilization. [PDF]

Front Immunol
Zhang Y, Wang D, Huang J, Wang Z, Zhu J, Lyu F, Jiang Z.   +6 more
europepmc   +1 more source