Results 281 to 290 of about 189,911 (333)

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Immune Landscape and Application of Immune Checkpoint Inhibitors in Clear Cell Renal Cell Carcinoma. [PDF]

Int J Mol Sci
An Y, Luo N.
europepmc   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

TIM-3 inhibition enhances breast tumor progression and metastasis: A paradoxical immune checkpoint response. [PDF]

J Biol Chem
Dolui B, Majumdar B, Bandyopadhyay A, Desai KV, Basu A.   +4 more
europepmc   +1 more source

IL-6 as a driver of bone invasion in IFIT2-depleted oral squamous cell carcinoma. [PDF]

Cancer Immunol Immunother
Lai KC, Hsieh CH, Wang CH, Hsiao SY, Kao WC, Chao CC, Chen PC.   +6 more
europepmc   +1 more source

Improvement of Treg Selectivity and Stability for Diabetes Mellitus Type 1 Treatment: Complex Approach for Perspective Technologies. [PDF]

Cells
Riabinin AA, Zhdanov DD, Blinova VG, Permyakova AA, Stulova AA, Rzhanova LA, Nikitochkina SY, Morgun EI, Vorotelyak EA.   +8 more
europepmc   +1 more source

Chemokine ligand 2: beyond chemotaxis-a multifaceted role in tumor progression. [PDF]

Front Immunol
Jin Y, Wang Y, Yang R.
europepmc   +1 more source

S1PR2 Signaling in the Lung: Understanding Its Role in Health and Disease. [PDF]

Cells
Ha AW, Garcia JGN, Dudek SM.
europepmc   +1 more source

Epigenetic alterations in <i>Helicobacter pylori</i> infection leading to gastric carcinogenesis: A systematic review. [PDF]

J Res Med Sci
Savitri CMA, Rahmawati LD, Awalia, Romadhon PZ, Waskito LA, Hidayat AA, Rezkitha YAA, Miftahussurur M, Yamaoka Y.   +8 more
europepmc   +1 more source