Results 101 to 110 of about 34,337 (216)
Circadian Clock Regulates Epidermal Endocrine System in Homeostatic Skin Pigmentation
Experimental Dermatology, Volume 35, Issue 6, June 2026.ABSTRACT The circadian clock regulates multiple physiological processes in the skin, including local hormone synthesis and pigmentation. However, how circadian regulation interacts with epidermal endocrine signalling in melanocytes remains unclear.
Anya Zhu +5 more
wiley +1 more source
Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases
The FASEB Journal, Volume 40, Issue 10, 31 May 2026.High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda +5 more
wiley +1 more source
Loss of dopamine disrupts circadian rhythms in a mouse model of Parkinson's disease
Neurobiology of Disease, 2014 Although a wide range of physiological functions regulated by dopamine (DA) display circadian variations, the role of DA in the generation and/or modulation of these rhythms is unknown.
Karim Fifel, Howard M. Cooper
doaj +1 more source
Structural and Dynamics Insights into Melatonin Binding to MT1 Receptor
ChemBioChem, Volume 27, Issue 10, 27 May 2026.In this study, we describe the structural and dynamic determinants governing MT1 binding by melatonin (MLT) by using an integrated approach that relies on the combination of on‐cell membrane nuclear magnetic resonance structural data with computational techniques.
Clementina Acconcia +10 more
wiley +1 more source
CIRCADIAN RHYTMICITY AND DEPRESSION
Zdravniški Vestnik, 2008 BACKGROUND Depression is the most common psychiatric syndrome treated on the primary level. Abnormal patterns of circadian rhythms are associated with a large variety of affective disorders including depression.
Peter Pregelj
doaj
Nature Communications, 2019 The suprachiasmatic nucleus (SCN) synchronises daily rhythms of behaviour and physiology to the light-dark cycle. Vasoactive intestinal peptide (VIP) is important for mediating SCN entrainment; however, the underlying mechanisms are incompletely ...
Ryan Hamnett +3 more
doaj +1 more source
Calretinin Neurons in the Rat Suprachiasmatic Nucleus [PDF]
Journal of Biological Rhythms, 2016 The hypothalamic suprachiasmatic nucleus (SCN), a circadian pacemaker, is present in all mammalian brains. It has a complex organization of peptide-containing neurons that is similar among species, but calcium-binding proteins are expressed variably.
openaire +2 more sources
Circadian clock network desynchrony promotes weight gain and alters glucose homeostasis in mice
Molecular Metabolism, 2019 Objective: A network of endogenous circadian clocks adapts physiology and behavior to recurring changes in environmental demands across the 24-hour day cycle. Circadian disruption promotes weight gain and type 2 diabetes development.
Isa Kolbe +3 more
doaj +1 more source
Frontiers in Neuroanatomy, 2015 Peroxisome proliferator-activated receptor gamma (PPARg) is a ligand-activated transcription factor that was originally identified as a regulator of peroxisome proliferation and adipocyte differentiation.
Yang eLiu +6 more
doaj +1 more source
eLife, 2017 The visual system consists of two major subsystems, image-forming circuits that drive conscious vision and non-image-forming circuits for behaviors such as circadian photoentrainment.
Kylie S Chew +17 more
doaj +1 more source