Results 81 to 90 of about 33,968 (213)

The Role of Mammalian Glial Cells in Circadian Rhythm Regulation

open access: yesNeural Plasticity, 2017
Circadian rhythms are biological oscillations with a period of about 24 hours. These rhythms are maintained by an innate genetically determined time-keeping system called the circadian clock.
Donají Chi-Castañeda, Arturo Ortega
doaj   +1 more source

Night‐to‐night rapid eye movement sleep variability: A relevant marker of early amyloid‐β deposition

open access: yesAlzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Sleep disturbances are prevalent in patients with Alzheimer's disease (AD) and may emerge before overt clinical symptoms. We characterized sleep alterations in cognitively unimpaired older adults with cerebral amyloid deposition, and assessed their associations with regional amyloid deposition and cognitive and psychoaffective ...
Blandine Montagne   +14 more
wiley   +1 more source

Rhythmic Trafficking of TRPV2 in the Suprachiasmatic Nucleus is Regulated by Prokineticin 2 Signaling

open access: yesJournal of Circadian Rhythms, 2015
The mammalian circadian clock is composed of single-cell oscillators. Neurochemical and electrical signaling among these oscillators is important for the normal expression of circadian rhythms.
Katherine J. Burton   +4 more
doaj   +1 more source

Mouse circadian plasma leptin and active ghrelin rhythms under ad libitum and scheduled feeding [PDF]

open access: yes, 2007
Thesis (M.S.) University of Alaska Fairbanks, 2007Light is the strongest timing cue for the circadian system, but non-photic cues can also entrain the master circadian clock, i.e., suprachiasmatic nuclei (SCN).
Wan, Haiting
core  

Brain-derived neurotrophic factor and neurotrophin receptors modulate glutamate-induced phase shifts of the suprachiasmatic nucleus [PDF]

open access: yes, 2006
Light information reaches the suprachiasmatic nucleus (SCN) through a subpopulation of retinal ganglion cells. Previous work raised the possibility that brain-derived neurotrophic factor (BDNF) and its high-affinity tropomyosin-related receptor kinase ...
Allen   +37 more
core   +1 more source

The Effects of Color Therapy on Fatigue, Depression, and Quality of Life in Parkinson's Patients: A Randomized Controlled Trial

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
Study Design: A randomized controlled trial conducted with 60 Parkinson's patients (30 intervention, 30 control). Intervention: An 8‐session color therapy program using purple, yellow, and orange lights (15 minutes each; total 45 minutes per session). Protocol: 3 sessions/week in the first two weeks, followed by 1 session/week in the fifth and seventh ...
Kübra Coskun, Gulcan Bahcecioglu Turan
wiley   +1 more source

Loss of dopamine disrupts circadian rhythms in a mouse model of Parkinson's disease

open access: yesNeurobiology of Disease, 2014
Although a wide range of physiological functions regulated by dopamine (DA) display circadian variations, the role of DA in the generation and/or modulation of these rhythms is unknown.
Karim Fifel, Howard M. Cooper
doaj   +1 more source

Network-mediated encoding of circadian time: The suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back [PDF]

open access: yes, 2014
The transcriptional architecture of intracellular circadian clocks is similar across phyla, but in mammals interneuronal mechanisms confer a higher level of circadian integration.
Azzi, Abdelhalim   +5 more
core   +2 more sources

Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling

open access: yesNature Communications, 2019
The suprachiasmatic nucleus (SCN) synchronises daily rhythms of behaviour and physiology to the light-dark cycle. Vasoactive intestinal peptide (VIP) is important for mediating SCN entrainment; however, the underlying mechanisms are incompletely ...
Ryan Hamnett   +3 more
doaj   +1 more source

Neurocardiovascular deficits in the Q175 mouse model of Huntington's disease. [PDF]

open access: yes, 2017
Cardiovascular dysautonomia as well as the deterioration of circadian rhythms are among the earliest detectable pathophysiological changes in individuals with Huntington's disease (HD). Preclinical research requires mouse models that recapitulate disease
Colwell, Christopher S   +7 more
core   +1 more source

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