Results 81 to 90 of about 335,217 (225)
Glia, Volume 74, Issue 10, October 2026.Bmal1 regulates astrocyte extracellular matrix (ECM) gene expression. Bmal1 deletion in astrocytes disrupts normal circadian rhythms in perineuronal nets (PNN) and reduces PNN content in the hippocampus. In parallel with loss of PNNs, deletion of the core circadian clock gene Bmal1 in astrocytes alters behavior and synaptic function in vivo.
Philip C. Smith +6 more
wiley +1 more source
Riding the Rhythm of Melatonin Through Pregnancy to Deliver on Time
Frontiers in Endocrinology, 2019 Pregnancy is influenced by the circadian (“circa” or approximately; diēm or day) system, which coordinates physiology and behavior with predictable daily changes in the environment such as light/dark cycles.
Ronald McCarthy +5 more
doaj +1 more source
International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1123-1132, October 2026.ABSTRACT Background Circadian clock disruption has emerged as a relevant axis in cancer; however, the expression patterns and diagnostic relevance of BMAL1 and CLOCK in multiple myeloma (MM) remain insufficiently defined. Methods BMAL1 and CLOCK mRNA expression was quantified by RT‐qPCR in bone marrow samples from 46 newly diagnosed MM patients and 13 ...
Hamide Albayrak +6 more
wiley +1 more source
, 2000 The suprachiasmatic nucleus of the hypothalamus is responsible for a 24-h rhythm in basal glucose levels in the rat. The neural pathways used by the suprachiasmatic nucleus to mediate this rhythm in plasma glucose have not yet been identified.
Kalsbeek, A. +9 more
core +1 more source
The choroid plexus is an important circadian clock component
Nature Communications, 2018 The suprachiasmatic nucleus (SCN) has been thought of as the master circadian clock, but peripheral circadian clocks do exist. Here, the authors show that the choroid plexus displays oscillations more robust than the SCN and that can be described as a ...
Jihwan Myung +10 more
doaj +1 more source
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Feeding female mice a high‐fat diet (HFD) lengthens endogenous circadian rhythmicity (tau) prior to HFD‐induced obesity (DIO), characterized by increased energy intake and reduced locomotor activity (A). While this DIO also occurs under a slower‐than‐tau 24 h T‐cycle, aligning T‐cycles to oscillate faster than the HFD‐lengthened tau postpones DIO—a ...
Anat Neumann, Roee Gutman
wiley +1 more source
, 2023 Original analysis code in this paper "Cholecystokinin Neurons in Mouse Suprachiasmatic Nucleus Regulate the Robustness of Circadian Clock"
Lucheng Xie
core +1 more source
The Suprachiasmatic Nucleus, Circadian Clocks, and the Liver [PDF]
Diabetes, 2013 The circadian clock system adapts phasic physiological activities, such as sleeping and eating, to environmental cycles. The “master clock” is in the suprachiasmatic nucleus (SCN) and the principal cue (Zeitgeber) is the light–dark cycle, around which most mammalian (and those of all living organisms) functions have evolved.
openaire +2 more sources
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.This cross‐sectional study involving 937 adults at high cardiovascular risk found a positive association between short sleep duration (< 7 h/night) and traditional and non‐traditional markers of adiposity (abdominal obesity, overweight, and high visceral adiposity index [VAI]), a non‐traditional marker of glucose metabolism disruption (high ...
Nathallia Maria Cotta e Oliveira +5 more
wiley +1 more source
Associations of Sleep and Shift Work With Osteoarthritis Risk
Arthritis Care &Research, Volume 78, Issue 9, Page 1209-1219, September 2026.Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik +5 more
wiley +1 more source