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Electrophysiology of the suprachiasmatic nucleus

, 2001
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Suprachiasmatic nucleus organization

Cell and Tissue Research, 2002
The suprachiasmatic nucleus (SCN) of the hypothalamus is a dominant circadian pacemaker in the mammalian brain controlling the rest-activity cycle and a series of physiological and endocrine functions to provide a foundation for the successful elaboration of adaptive sleep and waking behavior. The SCN is anatomically and functionally organized into two
Robert Y, Moore, Joan C, Speh, Rehana K, Leak   +2 more
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Suprachiasmatic Nucleus Organization

Chronobiology International, 1998
The suprachiasmatic nucleus (SCN) of the hypothalamus is a dominant circadian pacemaker in the mammalian brain controlling the rest-activity cycle and a series of physiological and endocrine functions to provide a foundation for the successful elaboration of adaptive sleep and waking behavior. The SCN is anatomically and functionally organized into two
R Y, Moore, R, Silver
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Functional development of fetal suprachiasmatic nucleus grafts in suprachiasmatic nucleus-lesioned rats

Brain Research Bulletin, 1993
Recovery of circadian drinking rhythms in suprachiasmatic nucleus (SCN)-lesioned rats after fetal SCN grafting was related to the immunocytochemical appearance and fiber outgrowth of vasopressin (VP)-, vasoactive intestinal polypeptide (VIP)-, and somatostatin (SOM)-containing neurons in the implants. At 4 weeks postgrafting, the first recovered animal
H A, Griffioen, H, Duindam, T P, Van der Woude, W J, Rietveld, G J, Boer   +4 more
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MULTIPLE OSCILLATORS IN THE SUPRACHIASMATIC NUCLEUS

Chronobiology International, 2001
The suprachiasmatic nucleus (SCN) of the hypothalamus is the site of the pacemaker that controls circadian rhythms of a variety of physiological functions. Data strongly indicate the majority of the SCN neurons express self-sustaining oscillations that can be detected as rhythms in the spontaneous firing of individual neurons.
T, Shirakawa, S, Honma, K, Honma
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Efferent Signals of the Suprachiasmatic Nucleus

Journal of Biological Rhythms, 1993
It is well established that the mammalian suprachiasmatic nucleus (SCN) is a biological pacemaker that entrains the activity of organisms to their environment and controls circadian rhyth-micity. However, neither the nature of these coupling signal or signals from the SCN, nor their target or targets in the brain, are well understood ...
R, Silver, J, LeSauter
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Transplanted Suprachiasmatic Nucleus Determines Circadian Period

Science, 1990
The pacemaker role of the suprachiasmatic nucleus in a mammalian circadian system was tested by neural transplantation by using a mutant strain of hamster that shows a short circadian period. Small neural grafts from the suprachiasmatic region restored circadian rhythms to arrhythmic animals whose own nucleus had been ablated.
M R, Ralph, R G, Foster, F C, Davis, M, Menaker   +3 more
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Suprachiasmatic nucleus: a central autonomic clock

Nature Neuroscience, 1999
Circadian rhythms are daily changes in behavior and physiology produced by the suprachiasmatic nucleus (SCN) even in the absence of external stimuli1, although photic input from the retina to the SCN entrains these changes to a 24-hour cycle. The SCN modulates autonomic and neuroendocrine function to prepare for diurnal or nocturnal changes in behavior,
T, Ueyama, K E, Krout, X V, Nguyen, V, Karpitskiy, A, Kollert, T C, Mettenleiter, A D, Loewy   +6 more
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The Suprachiasmatic Nucleus

2010
Diurnal variations in physiology and behavior are ubiquitous in higher organisms. Although some rhythms are driven directly by geophysical cycles of light or temperature, most are generated by internal timers, commonly referred to as biological clocks.
Gabriella Lundkvist, Gene D. Block
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Neurogenesis of the hamster suprachiasmatic nucleus

Brain Research, 1990
Neurogenesis of the hypothalamic suprachiasmatic nucleus (SCN) was described in the Syrian hamster (Mesocricetus auratus) using tritiated [3H]thymidine autoradiography. Pregnant hamsters were given single intraperitoneal injections of [3H]thymidine at different times during prenatal development, and labeled cells were analyzed in the offspring of 4-5 ...
F C, Davis, R, Boada, J, LeDeaux
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