Results 221 to 230 of about 36,798 (270)
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Suprachiasmatic Nucleus Neurons Are Glucose Sensitive
Journal of Biological Rhythms, 1997The suprachiasmatic nucleus (SCN) in the hypothalamus serves as the pacemaker for mammalian circadian rhythms. In a hamster brain slice preparation, the authors were able to record spontaneous activity from SCN cells for up to 4 days in vitro and verify a self-sustained rhythm in firing.
Hall, Adam C. +4 more
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Primary cell culture of suprachiasmatic nucleus
Brain Research Bulletin, 2003In mammals, the suprachiasmatic nucleus (SCN) contains a biological clock that drives circadian rhythms in vivo and in vitro. Primary dissociated neuronal culture is a useful research tool, which allows cell-by-cell morphological and physiological study of the SCN.
Daan, Ren, Joseph D, Miller
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Resetting the suprachiasmatic nucleus clock
Frontiers in Bioscience, 2004Recent research on the cellular basis of circadian rhythmicity has stressed the importance of clock genes for the maintenance of normal rhythmicity. There have been tremendous advances in our understanding of the inter-relationships of the various genes known to generate the rhythms.
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Functional Morphology of the Suprachiasmatic Nucleus
Frontiers in Neuroendocrinology, 1999In mammals, the biological clock (circadian oscillator) is situated in the suprachiasmatic nucleus (SCN), a small bilaterally paired structure just above the optic chiasm. Circadian rhythms of sleep-wakefulness and hormone release disappear when the SCN is destroyed, and transplantation of fetal or neonatal SCN into an arrhythmic host restores ...
Y, Ibata +11 more
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Neuroscience, 1999
It was investigated whether grafts of the suprachiasmatic nucleus could re-instate circadian rhythmicity in the absence of its endogenous vasopressin production and whether the restored rhythm would have the long period length of the donor. Grafts of 17-days-old vasopressin-deficient homozygous Brattleboro rat fetuses, homotopically placed in ...
G J, Boer +4 more
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It was investigated whether grafts of the suprachiasmatic nucleus could re-instate circadian rhythmicity in the absence of its endogenous vasopressin production and whether the restored rhythm would have the long period length of the donor. Grafts of 17-days-old vasopressin-deficient homozygous Brattleboro rat fetuses, homotopically placed in ...
G J, Boer +4 more
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Synaptology of the rat suprachiasmatic nucleus
Cell and Tissue Research, 1976Within the suprachiasmatic nucleus (SCN) of the rat the fine structure of the synapses and some features of their topological arrangement were studied. Five types of synapses could be distinguished with certainty: A. Two types of Gray-type-I (GTI) or asymmetrical synapses (approximately 33%).
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Melatonin receptors in the mammalian suprachiasmatic nucleus
Behavioural Brain Research, 1995The SCN of the hypothalamus, the site of the circadian pacemaker in mammals, is endowed with melatonin receptors of the ML-1 subtype. Here, we present evidence suggesting that activation of melatonin receptors in the SCN regulates circadian rhythms of behavior in the mouse. In a paradigm simulating a eastbound transmeridian flight, timed administration
M L, Dubocovich +2 more
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Serotonin innervation of the primate suprachiasmatic nucleus
Brain Research, 2004The suprachiasmatic nucleus (SCN) in rodents receives a dense innervation from serotonin neurons of the midbrain raphe. This projection overlaps the terminal field of the retinohypothalamic tract in the SCN core, the central part of the nucleus characterized by a population of vasoactive intestinal polypeptide (VIP)-containing neurons.
Robert Y, Moore, Joan C, Speh
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Immunocytochemistry on Suprachiasmatic Nucleus Slices
2007Immunocytochemistry (ICC) is a sensitive and powerful method that is used to localize and identify cells containing a particular antigen. This chapter is dedicated to ICC of suprachiasmatic nucleus (SCN) slices. After a brief introduction to the technique, the materials and methods sections describe two different methods to obtain SCN slices--the first
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Suprachiasmatic nucleus in sleep–wake regulation
Sleep Medicine, 2007The evolution of animals is a consequence of selective specialization of cells, tissues, functional systems, and behavior. The objective of all life is successful reproduction and maintenance of the species. In order to accomplish this, all animals have evolved a division of behavior into two fundamental behavioral states: one characterized by the ...
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