Results 11 to 20 of about 15,528 (133)

Progressive Supranuclear Palsy [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1987
ABSTRACT:Progressive supranuclear palsy (PSP) was first recognized as a distinct morbid entity by Richardson, Steele and Olszewski a quarter century ago. Subsequent experience has confirmed and extended their original observations. PSP has become familiar as a chronic progressive disorder with extrapyramidal rigidity, bradykinesia, gait impairment ...
Roger C. Duvoisin, Lawrence I. Golbe, Frederick E. Lepore   +2 more
openaire   +3 more sources

The Significance of Asymmetry in the Assessment of Brain Perfusion in Atypical Tauopathic Parkinsonian Syndromes

Diagnostics, 2022
Progressive supranuclear palsy syndrome (PSPS) and corticobasal syndrome (CBS) are clinical manifestations of tauopathic Parkinsonian syndromes. Due to their overlapping symptomatology, the differential diagnosis of these entities may be difficult when ...
Piotr Alster, Natalia Madetko, Bartosz Migda, Michał Nieciecki, Michał Kutyłowski, Leszek Królicki, Andrzej Friedman   +6 more
doaj   +1 more source

Identification of multiple system atrophy mimicking Parkinson's disease or progressive supranuclear palsy [PDF]

, 2021
WWe studied a subset of patients with autopsy-confirmed multiple system atrophy who presented a clinical picture that closely resembled either Parkinson’s disease or progressive supranuclear palsy.
Asi, YT, Bettencourt, C, De Pablo-Fernández, E, Foti, SC, Holton, JL, Jaunmuktane, Z, Lees, AJ, Ling, H, Miki, Y, Oliveira, MCB, Quinn, N, Strand, KM, Tsushima, E, Wakabayashi, K, Warner, TT, Yamamoto, AK   +15 more
core   +1 more source

Neuropsychiatric disturbances in atypical Parkinsonian disorders [PDF]

, 2018
Multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD) are the most common atypical parkinsonisms. These disorders are characterized by varying combinations of autonomic, cerebellar and pyramidal system ...
Belvisi, Daniele, Berardelli, Isabella, Fabbrini, Andrea, Fabbrini, Giovanni, Pasquini, Massimo, Pompili, Maurizio, Suppa, Antonio   +6 more
core   +1 more source

Atypical parkinsonism: An Update. [PDF]

, 2013
Purpose of review: This update discusses novel aspects on genetics, diagnosis, and treatments of atypical parkinsonism published over the past 2 years. Recent findings: A genome-wide association study identified new genetic risk factors for progressive ...
Hoeglinger, GU, Stamelou, M
core   +1 more source

9.4 T MR microscopy of the substantia nigra with pathological validation in controls and disease

NeuroImage: Clinical, 2017
Background: The anatomy of the substantia nigra on conventional MRI is controversial. Even using histological techniques it is difficult to delineate with certainty from surrounding structures.
LA Massey, MA Miranda, O Al-Helli, HG Parkes, JS Thornton, P-W So, MJ White, L Mancini, C Strand, J Holton, AJ Lees, T Revesz, TA Yousry   +12 more
doaj   +1 more source

Abnormal resting-state functional connectivity in progressive supranuclear palsy and corticobasal syndrome [PDF]

, 2017
Background: Pathological and MRI-based evidence suggests that multiple brain structures are likely to be involved in functional disconnection between brain areas. Few studies have investigated resting-state functional connectivity (rsFC) in progressive
Berardelli, Alfredo, Bharti, Komal, Bologna, Matteo, Giannã¬, Costanza, Pantano, Patrizia, Petsas, Nikolaos, Piattella, Maria Cristina, Suppa, Antonio, Tona, Francesca, Upadhyay, Neeraj   +9 more
core   +2 more sources

Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. [PDF]

, 2016
BackgroundClinical diagnosis of parkinsonian syndromes like Parkinson's disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Boman, Andrea, Boxer, Adam, Karydas, Anna, Kågedal, Katarina, Miller, Bruce, Rojas, Julio C, Seeley, William W, Svenningsson, Per, Svensson, Samuel   +8 more
core   +1 more source

Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy.

PLoS ONE, 2019
Radiological biomarkers have been reported for multiple system atrophy and progressive supranuclear palsy, but serum/plasma biomarkers for each disorder have not been established.
Akio Mori, Kei-Ichi Ishikawa, Shinji Saiki, Taku Hatano, Yutaka Oji, Ayami Okuzumi, Motoki Fujimaki, Takahiro Koinuma, Shin-Ichi Ueno, Yoko Imamichi, Nobutaka Hattori   +10 more
doaj   +1 more source

A longitudinal study of motor, oculomotor and cognitive function in progressive supranuclear palsy.

PLoS ONE, 2013
ObjectiveWe studied the annual change in measures of motor, oculomotor and cognitive function in progressive supranuclear palsy. This had twin objectives, to assess the potential for clinical parameters to monitor disease progression in clinical trials ...
Boyd C P Ghosh, Roger H S Carpenter, James B Rowe   +2 more
doaj   +1 more source