Results 11 to 20 of about 44,405 (256)

Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning [PDF]

Brain Communications, 2023
To better understand the pathological and phenotypic heterogeneity of progressive supranuclear palsy and the links between the two, we applied a novel unsupervised machine learning algorithm (Subtype and Stage Inference) to the largest MRI data set to ...
Alexander, Daniel C, Bocchetta, Martina, Boxer, Adam L, Cash, David M, Heuer, Hilary, Morris, Huw R, Oxtoby, Neil, PROSPECT Consortium, 4RTNI Consortium, Rohrer, Jonathan D, Rowe, James B, Scotton, William J, Shand, Cameron, Todd, Emily, VandeVrede, Lawren, Wijeratne, Peter A, Young, Alexandra L   +15 more
core   +2 more sources

Identification of multiple system atrophy mimicking Parkinson's disease or progressive supranuclear palsy [PDF]

Brain : a journal of neurology, 2021
WWe studied a subset of patients with autopsy-confirmed multiple system atrophy who presented a clinical picture that closely resembled either Parkinson’s disease or progressive supranuclear palsy.
Asi, YT, Bettencourt, C, De Pablo-Fernández, E, Foti, SC, Holton, JL, Jaunmuktane, Z, Lees, AJ, Ling, H, Miki, Y, Oliveira, MCB, Quinn, N, Strand, KM, Tsushima, E, Wakabayashi, K, Warner, TT, Yamamoto, AK   +15 more
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Simultaneous mixed phenotype and neuroimaging of progressive supranuclear palsy, progressive ataxia and palatal tremor: two different faces of tauopathies. [PDF]

Arq Neuropsiquiatr, 2022
A 74-year-old woman was referred with a six-month history of progressive gait disturbance and falls.
Freitas LF, Carvalho VM, Pedroso JL, Duarte ML, Massaud RM.   +4 more
europepmc   +2 more sources

18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy. [PDF]

Brain : a journal of neurology, 2016
The ability to assess the distribution and extent of tau pathology in Alzheimer's disease and progressive supranuclear palsy in vivo would help to develop biomarkers for these tauopathies and clinical trials of disease-modifying therapies.
Aigbirhio, Franklin I, Allinson, Kieren SJ, Arnold, Robert, Bevan-Jones, W Richard, Borchert, Robin J, Cope, Thomas E, Fryer, Tim D, Hong, Young T, Jones, P Simon, Mak, Elijah, O'Brien, John T, Passamonti, Luca, Rowe, James B, Sami, Saber, Su, Li, Surendranathan, Ajenthan, Vázquez Rodríguez, Patricia, Williamson, David   +17 more
core   +2 more sources

Predictors of survival in progressive supranuclear palsy and multiple system atrophy: a systematic review and meta-analysis [PDF]

Journal of Neurology Neurosurgery & Psychiatry, 2017
Objective To undertake a systematic review and meta-analysis of studies that investigated prognostic factors and survival in patients with progressive supranuclear palsy (PSP) and multiple system atrophy (MSA).
Ben-Shlomo, Bensimon, Birdi, Bower, Calandra-Buonaura, Chiu, Coon, dell'Aquila, Donker Kaat, Figueroa, Gilman, Gilman, Golbe, Golbe, Goldstein, Hayden, Hellwig, Higgins, Jecmenica-Lukic, Kim, Kim, Klockgether, Krim, Lalich, Litvan, Litvan, Litvan, Low, Maher, Moher, Nath, Nath, O'Sullivan, Ozawa, Ozawa, Papp, Payan, Peter Nigel Leigh, Respondek, Romi Anirban Saha, Roncevic, Saito, Sakushima, Santacruz, Schrag, Schrag, Schulz, Silber, Stella Andrea Glasmacher, Tada, Testa, Testa, Tierney, Watanabe, Wenning, Wenning, Williams, Yamaguchi   +57 more
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Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy

Journal of Neurology Neurosurgery & Psychiatry, 2022
Objectives This longitudinal study compared emerging plasma biomarkers for neurodegenerative disease between controls, patients with Alzheimer’s disease (AD), Lewy body dementia (LBD), frontotemporal dementia (FTD) and progressive supranuclear palsy (PSP)
L. Chouliaras, A. Thomas, M. Malpetti, P. Donaghy, J. Kane, E. Mak, G. Savulich, M. Prats-Sedano, A. Heslegrave, H. Zetterberg, L. Su, J. Rowe, J. O'Brien   +12 more
semanticscholar   +1 more source

Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy

Acta Neuropathologica, 2022
Neuropathologic criteria for progressive supranuclear palsy (PSP) proposed by a National Institute of Neurological Disorders and Stroke (NINDS) working group were published in 1994 and based on the presence of neurofibrillary tangles in basal ganglia and
S. Roemer, L. Grinberg, J. Crary, W. Seeley, A. Mckee, G. Kovacs, T. Beach, C. Duyckaerts, I. Ferrer, E. Gelpí, Edward B. Lee, T. Révész, C. White, Mari Yoshida, F. Pereira, Kristen Whitney, Nikhil B. Ghayal, D. Dickson   +17 more
semanticscholar   +1 more source

Progressive supranuclear palsy-progressive non-fluent aphasia syndrome

Definitions, 2020
PSP-progressive non fluent aphasia (PSP-PNFA) is an atypical variant of progressive supranuclear palsy (PSP; see this term), a rare late-onset neurodegenerative disease.

semanticscholar   +1 more source

Development and Validation of Automated Magnetic Resonance Parkinsonism Index 2.0 to Distinguish Progressive Supranuclear Palsy‐Parkinsonism From Parkinson's Disease

Movement Disorders, 2022
Differentiating progressive supranuclear palsy‐parkinsonism (PSP‐P) from Parkinson's disease (PD) is clinically challenging.
A. Quattrone, M. Bianco, A. Antonini, D. Vaillancourt, K. Seppi, R. Ceravolo, A. Strafella, G. Tedeschi, A. Tessitore, R. Cilia, M. Morelli, Salvatore Nigro, B. Vescio, P. Arcuri, R. de Micco, M. Cirillo, Luca Weis, E. Fiorenzato, R. Biundo, Roxana G. Burciu, F. Krismer, Nikolaus R. McFarland, Christoph Mueller, E. Gizewski, M. Cosottini, E. Del Prete, S. Mazzucchi, A. Quattrone   +27 more
semanticscholar   +1 more source

A data-driven model of brain volume changes in progressive supranuclear palsy

Brain Communications, 2022
The most common clinical phenotype of progressive supranuclear palsy is Richardson syndrome, characterized by levodopa unresponsive symmetric parkinsonism, with a vertical supranuclear gaze palsy, early falls and cognitive impairment.
W. Scotton, M. Bocchetta, E. Todd, D. Cash, N. Oxtoby, L. Vandevrede, H. Heuer, Prospect Consortium, D. Consortium, Alexander, J. Rowe, H. Morris, A. Boxer, J. Rohrer, P. Wijeratne   +14 more
semanticscholar   +1 more source