Results 21 to 30 of about 44,405 (256)

Autonomic dysfunction in progressive supranuclear palsy

Journal of Neurology, 2022
Background The degree of involvement of the autonomic nervous system in progressive supranuclear palsy (PSP) has been investigated in several studies, often providing conflicting results.
F. Baschieri, M. Vitiello, P. Cortelli, G. Calandra-Buonaura, F. Morgante   +4 more
semanticscholar   +1 more source

Long‐Duration Progressive Supranuclear Palsy: Clinical Course and Pathological Underpinnings

Annals of Neurology, 2022
To identify the clinical characteristics of the subgroup of benign progressive supranuclear palsy with particularly long disease duration; to define neuropathological determinants underlying variability in disease duration in progressive supranuclear ...
Milica Jecmenica Lukic, G. Respondek, C. Kurz, Y. Compta, E. Gelpí, L. Ferguson, A. Rajput, C. Troakes, J. V. van Swieten, A. Giese, S. Roeber, J. Herms, T. Arzberger, G. Höglinger   +13 more
semanticscholar   +1 more source

Distribution patterns of tau pathology in progressive supranuclear palsy

Acta Neuropathologica, 2020
Progressive supranuclear palsy (PSP) is a 4R-tauopathy predominated by subcortical pathology in neurons, astrocytes, and oligodendroglia associated with various clinical phenotypes. In the present international study, we addressed the question of whether
G. Kovacs, M. Lukić, D. Irwin, T. Arzberger, G. Respondek, Eddie B. Lee, D. Coughlin, A. Giese, M. Grossman, C. Kurz, C. Mcmillan, E. Gelpí, Y. Compta, J. V. van Swieten, Laura Donker Laat, C. Troakes, S. Al-Sarraj, John L. Robinson, S. Roeber, S. Xie, V. Lee, J. Trojanowski, G. Höglinger   +22 more
semanticscholar   +1 more source

Progressive supranuclear palsy

Hospital Medicine, 2003
Progressive supranuclear palsy, also known as Steele–Richardson–Olszewski syndrome, is an uncommon neurodegenerative parkinsonian disorder that starts in middle and late life, and is frequently misdiagnosed as Parkinson's disease. This review will cover the epidemiology, clinical picture, differential diagnosis and management of patients with ...
Douglas G. Cole, Nutan Sharma
  +5 more sources

Clinical Conditions “Suggestive of Progressive Supranuclear Palsy”—Diagnostic Performance [PDF]

, 2020
Background: The Movement Disorder Society diagnostic criteria for progressive supranuclear palsy introduced the diagnostic certainty level “suggestive of progressive supranuclear palsy” for clinical conditions with subtle signs, suggestive of the disease.
Arzberger, T. (T.), Compta, Y. (Yaroslau), Ferguson, L.W. (Leslie W.), Gelpi, E. (Ellen), Giese, A. (Armin), Grimm, M.-J. (Max-Joseph), Grossman, M. (Murray), Hoglinger, G. (Gunter), Irwin, D.J. (David J.), Meissner, W.G. (Wassilios G.), Nilsson, C. (Christer), Pantelyat, A. (Alexander), Piot, I. (Ines), Rajput, A. (Alex), Respondek, G. (Gesine), Roeber, S. (Sigrun), Rowe, J.B. (James), Stamelou, M. (Maria), Swieten, J.C. (John) van, Troakes, C. (Claire)   +19 more
core   +4 more sources

Neuropsychiatric disturbances in atypical Parkinsonian disorders [PDF]

, 2018
Multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD) are the most common atypical parkinsonisms. These disorders are characterized by varying combinations of autonomic, cerebellar and pyramidal system ...
Belvisi, Daniele, Berardelli, Isabella, Fabbrini, Andrea, Fabbrini, Giovanni, Pasquini, Massimo, Pompili, Maurizio, Suppa, Antonio   +6 more
core   +1 more source

Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy

JAMA Neurology, 2020
This cross-sectional study investigates the potential of novel tau radiotracer 18F-PI-2620 as a biomarker in patients with clinically diagnosed progressive supranuclear palsy.
M. Brendel, H. Barthel, Thilo van Eimeren, K. Marek, L. Beyer, M. Song, Carla Palleis, M. Gehmeyr, U. Fietzek, G. Respondek, J. Sauerbeck, A. Nitschmann, C. Zach, J. Hammes, M. Barbe, O. Onur, F. Jessen, D. Saur, M. Schroeter, J. Rumpf, M. Rullmann, A. Schildan, M. Patt, B. Neumaier, O. Barret, Jennifer Madonia, D. Russell, A. Stephens, S. Roeber, J. Herms, K. Bötzel, J. Classen, P. Bartenstein, V. Villemagne, J. Levin, G. Höglinger, A. Drzezga, J. Seibyl, O. Sabri   +38 more
semanticscholar   +1 more source

Machine learning‐based decision tree classifier for the diagnosis of progressive supranuclear palsy and corticobasal degeneration

Neuropathology and Applied Neurobiology, 2021
This study aimed to clarify the different topographical distribution of tau pathology between progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) and establish a machine learning‐based decision tree classifier.
S. Koga, Xiaolai Zhou, D. Dickson
semanticscholar   +1 more source

Genetics of Progressive Supranuclear Palsy [PDF]

Journal of Movement Disorders, 2015
Progressive supranuclear palsy (PSP) is a neurodegenerative syndrome that is clinically characterized by progressive postural instability, supranuclear gaze palsy, parkinsonism and cognitive decline.
Sun Young Im, Young Eun Kim, Yun Joong Kim   +2 more
doaj   +1 more source

Atypical parkinsonism: An Update. [PDF]

, 2013
Purpose of review: This update discusses novel aspects on genetics, diagnosis, and treatments of atypical parkinsonism published over the past 2 years. Recent findings: A genome-wide association study identified new genetic risk factors for progressive ...
Hoeglinger, GU, Stamelou, M
core   +1 more source