Paraventricular nucleus Sim1 neuron ablation mediated obesity is resistant to high fat diet. [PDF]
Single minded 1 (SIM1) is a transcription factor involved in brain patterning and control of energy balance. In humans, haploinsufficiency of SIM1 causes early-onset obesity.
Dong Xi +4 more
doaj +1 more source
Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels [PDF]
There is evidence that chronic ethanol treatment (CET) disrupts the biological rhythms of various brain functions and behaviors. Because the suprachiasmatic nucleus (SCN) is widely recognized as the dominant pacemaker of the circadian system, we have ...
Almeida, OFX +5 more
core +1 more source
Neuronal Activation in the Central Nervous System of Rats in the Initial Stage of Chronic Kidney Disease-Modulatory Effects of Losartan and Moxonidine. [PDF]
The effect of mild chronic renal failure (CRF) induced by 4/6-nephrectomy (4/6NX) on central neuronal activations was investigated by c-Fos immunohistochemistry staining and compared to sham-operated rats.
Bahner U +6 more
core +15 more sources
Development of the early axon scaffold in the rostral brain of the small spotted cat shark (Scyliorhinus canicula) embryo [PDF]
International audienceThe cat shark is increasingly used as a model for Chondrichthyes, an evolutionarily important sister group of the bony vertebrates that include teleosts and tetrapods.
Schubert, Frank +2 more
core +5 more sources
Olfactory sensory neurons which express a member from the OR37 subfamily of odorant receptor genes are wired to the main olfactory bulb in a unique monoglomerular fashion; from these glomeruli an untypical connectivity into higher brain centers exists ...
Andrea eBader +3 more
doaj +1 more source
Reduced osmoresponsiveness in magnocellular neuroendocrine neurones during chronic salt-loading. [PDF]
Abstract figure legend We conducted a large systematic survey of the physiological and electrophysiological characteristics of the magnocellular neurosecretory neurones of the supraoptic nucleus in euhydrated and salt‐loaded conditions. Our in vivo electrophysiological recordings show that, after 7 days of salt‐loading, the neuronal responsiveness to ...
Lozic M +5 more
europepmc +2 more sources
Roles of estrogen receptor-alpha in mediating life span: the hypothalamic deregulation hypothesis. [PDF]
In several species caloric restriction (CR) extends life span. In this paper we integrate data from studies on CR and other sources to articulate the hypothalamic deregulation hypothesis by which estrogen receptor-alpha (ER-α) signaling in the ...
Barakat, Rita +6 more
core +1 more source
Due to phoenixin’s role in restraint stress and glucocorticoid stress, as well as its recently shown effects on the inflammasome, we aimed to investigate the effects of lipopolysaccharide (LPS)-induced inflammatory stress on the activity of brain nuclei ...
Tiemo Friedrich +5 more
doaj +1 more source
Chickens cannot independently thermoregulate at hatch and lack opportunity to behaviorally thermoregulate with a hen in the egg layer industry, thus barns are heated to thermoneutral temperatures.
Rebecca E. Nordquist +4 more
doaj +1 more source
Syndrome of Inappropriate Antidiuretic Hormone Secretion Associated with Pramipexole in a Patient with Parkinson’s Disease [PDF]
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) can be caused by a variety of drugs. Dopaminergic drugs might enhance the secretion of the antidiuretic hormone arginine vasopressin by reducing γ-amino butyric acid release through the
Yoonjae Choi +8 more
doaj +1 more source

